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Topic · Rheumatology

Bone and Dental Protein Studies

Bone and Dental Protein Studies is a research topic within Rheumatology. Science Explorer counts 19k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the multifaceted role of osteopontin in biomineralization, inflammation, immune regulation, cancer progression, and cell signaling. It delves into its influence on various conditions such as dentinogenesis imperfecta, tumor metastasis, and autoimmune demyelinating disease. The papers also discuss the involvement of matricellular proteins in modulating cell function and tissue response to injury.

  • Osteopontin
  • Biomineralization
  • Inflammation
  • Matricellular Proteins
  • Cell Signaling
  • Cancer Progression
  • Immune Regulation
  • Tumor Metastasis
  • Dentinogenesis Imperfecta
  • Extracellular Modulators
Research works
19k
fractional, since 1950
In the world top 10%
1.9k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+8%
the tick is no change
Largest producer
China
36% of the 10 largest, 2022-now
Bone and Dental Protein Studies

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Bone and Dental Protein Studies research?

By volume, China and the United States publish the most (716 and 352 works in 2022-now).

By volume, 2022-now

  1. 1 China 716 works
  2. 2 United States 352 works
  3. 3 India 198 works
  4. 4 Brazil 187 works
  5. 5 Japan 137 works
  6. 6 Germany 92 works
  7. 7 Türkiye 88 works
  8. 8 United Kingdom 79 works
  9. 9 France 73 works
  10. 10 Egypt 64 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 36.0%United States: 17.7%India: 10.0%Brazil: 9.4%6 others listed: 26.8%36%largest
China716 · 36.0%United States352 · 17.7%India198 · 10.0%Brazil187 · 9.4%6 others listed533 · 26.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Bone and Dental Protein Studies research?

By volume in 2022-now, Stomatology Hospital publishes the most Bone and Dental Protein Studies research, followed by Sichuan University and Universidade de São Paulo.

By volume, 2022-now

  1. 1 Stomatology HospitalChina 37 works
  2. 2 Sichuan UniversityChina 32 works
  3. 3 Universidade de São PauloBrazil 23 works
  4. 4 Shanghai Jiao Tong UniversityChina 23 works
  5. 5 Wuhan UniversityChina 19 works
  6. 6 Centre National de la Recherche ScientifiqueFrance 18 works
  7. 7 Sun Yat-sen UniversityChina 15 works
  8. 8 Nanjing Medical UniversityChina 15 works
  9. 9 Universidade Estadual Paulista (Unesp)Brazil 15 works
  10. 10 Peking UniversityChina 14 works

Who are the leading researchers in Bone and Dental Protein Studies?

The most-cited researchers publishing on Bone and Dental Protein Studies include Hermann Brenner, Matthias Mann and Richard A. Gibbs.

  1. 1 Hermann Brenner Germany 343k citations
  2. 2 Matthias Mann Germany 308k citations
  3. 3 Richard A. Gibbs United States 292k citations
  4. 4 Yousef Saleh Khader Jordan 274k citations
  5. 5 Amirhossein Sahebkar Iran 258k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Bone and Dental Protein Studies?

The most cited paper in Bone and Dental Protein Studies is "Bone: Formation by Autoinduction" (Marshall R. Urist, 1965), with 5,578 citations. Next come "New Perspectives in Cell Adhesion: RGD and Integrins" (4,905) and "Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo" (4,630).

Most cited papers
#PaperReleasedCitations
1 Bone: Formation by Autoinduction Marshall R. Urist · Science 12 Nov 1965 5,578
2 New Perspectives in Cell Adhesion: RGD and Integrins Erkki I. Ruoslahti, Michael D. Pierschbacher · Science 23 Oct 1987 4,905
3 Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo Stan Gronthos, Mahesh H. Mankani, Jaime S. Brahim et al. · Proceedings of the National Academy of Sciences Open access 21 Nov 2000 4,630
4 Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts Toshihisa Komori, Hideshi Yagi, Shogo Nomura et al. · Cell Open access May 1997 4,270
5 Novel Regulators of Bone Formation: Molecular Clones and Activities John M. Wozney, Vicki Rosen, Anthony J. Celeste et al. · Science 16 Dec 1988 3,927
All 100 most cited papers, with filters and sorting

Where is Bone and Dental Protein Studies research done?

The largest centres of Bone and Dental Protein Studies research in 2022-now are Beijing (China), Xi'an (China), Shanghai (China) and São Paulo (Brazil).

Largest cities, 2022-now

  1. 1 BeijingChina 73 works
  2. 2 Xi'anChina 67 works
  3. 3 ShanghaiChina 56 works
  4. 4 São PauloBrazil 52 works
  5. 5 GuangzhouChina 41 works
  6. 6 ChennaiIndia 38 works
  7. 7 ChengduChina 34 works
  8. 8 WuhanChina 34 works
  9. 9 ParisFrance 31 works
  10. 10 HangzhouChina 28 works
See Bone and Dental Protein Studies on the map

Where is the best place to study Bone and Dental Protein Studies?

Among universities, judged by research, Sichuan University, Shanghai Jiao Tong University and University of Hong Kong score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 17.17%fractional works in this field (log) →share of work in the world top 10% →Zhejiang UniversityUniversity of Hong K…Shanghai Jiao Tong U…Sichuan University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Sichuan UniversityChina 76.516.0%5.6×32 +22.0%
2Shanghai Jiao Tong UniversityChina 67.616.4%3.1×23 +26.3%
3University of Hong KongChina 64.119.8%3.7×9 +92.6%
4Zhejiang UniversityChina 63.821.2%2.0×14 +24.9%
5Capital Medical UniversityChina 63.021.6%4.8×13 +26.3%
6Sun Yat-sen UniversityChina 57.419.3%2.9×15 +15.2%
7McGill UniversityCanada 57.014.7%3.9×10 -10.8%
8Air Force Medical UniversityChina 55.118.8%24.8×10 +87.7%
9Wuhan UniversityChina 54.210.2%5.3×19 +147.8%
10Southern Medical UniversityChina 52.013.7%8.6×14 +16.3%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Bone and Dental Protein Studies, country by country

Is Bone and Dental Protein Studies research growing?

Output in 2022-2025 was 8% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Bone and Dental Protein Studies.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Bone and Dental Protein Studies as a percentage of every work published that year, 0.011% in 2024.

still counting0.020%0.040%Bone and Dental Protein Studies0.013% in 202519801990200020102020

Fractional works of Bone and Dental Protein Studies over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Bone and Dental Protein Studies10.1% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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