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Topic · Rheumatology

IgG4-Related and Inflammatory Diseases

IgG4-Related and Inflammatory Diseases is a research topic within Rheumatology. Science Explorer counts 14k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the diagnosis and management of IgG4-related disease, including autoimmune pancreatitis, inflammatory myofibroblastic tumor, and sclerosing cholangitis. It discusses the diagnostic criteria, pathological features, clinical profiles, and therapeutic approaches such as rituximab therapy for this systemic disease.

  • IgG4-Related Disease
  • Autoimmune Pancreatitis
  • Inflammatory Myofibroblastic Tumor
  • Sclerosing Cholangitis
  • Diagnostic Criteria
  • Immunoglobulin G4
  • Pathological Features
  • Rituximab Therapy
  • Clinical Profile
  • Systemic Disease
Research works
14k
fractional, since 1950
In the world top 10%
1.4k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+16%
the tick is no change
Largest producer
United States
26% of the 10 largest, 2022-now
IgG4-Related and Inflammatory Diseases

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead IgG4-Related and Inflammatory Diseases research?

By volume, the United States and China publish the most (669 and 617 works in 2022-now).

By volume, 2022-now

  1. 1 United States 669 works
  2. 2 China 617 works
  3. 3 Japan 401 works
  4. 4 India 245 works
  5. 5 Spain 122 works
  6. 6 Italy 112 works
  7. 7 United Kingdom 100 works
  8. 8 Türkiye 96 works
  9. 9 Germany 93 works
  10. 10 France 92 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 26.3%China: 24.2%Japan: 15.8%India: 9.6%6 others listed: 24.2%26%largest
United States669 · 26.3%China617 · 24.2%Japan401 · 15.8%India245 · 9.6%6 others listed616 · 24.2%

Shares of the rows listed above, not of the whole node.

Which institutions lead IgG4-Related and Inflammatory Diseases research?

By volume in 2022-now, Harvard University publishes the most IgG4-Related and Inflammatory Diseases research, followed by Capital Medical University and Mayo Clinic.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 37 works
  2. 2 Capital Medical UniversityChina 36 works
  3. 3 Mayo ClinicUnited States 36 works
  4. 4 All India Institute of Medical SciencesIndia 27 works
  5. 5 Peking UniversityChina 25 works
  6. 6 Sichuan UniversityChina 23 works
  7. 7 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 22 works
  8. 8 Tsinghua UniversityChina 20 works
  9. 9 Sun Yat-sen UniversityChina 18 works
  10. 10 Zhejiang UniversityChina 17 works

Who are the leading researchers in IgG4-Related and Inflammatory Diseases?

The most-cited researchers publishing on IgG4-Related and Inflammatory Diseases include Giuseppe Remuzzi, Kai You Wang and Alberto Arduan Ortiz.

  1. 1 Giuseppe Remuzzi Italy 328k citations
  2. 2 Kai You Wang China 224k citations
  3. 3 Alberto Arduan Ortiz Spain 219k citations
  4. 4 Marc Ladanyi United States 217k citations
  5. 5 Ralph H. Hruban United States 209k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in IgG4-Related and Inflammatory Diseases?

The most cited paper in IgG4-Related and Inflammatory Diseases is "High Serum IgG4 Concentrations in Patients with Sclerosing Pancreatitis" (Hideaki Hamano, Shigeyuki Kawa, Akira C. Horiuchi et al., 2001), with 2,725 citations. Next come "IgG4-Related Disease" (2,629) and "Consensus statement on the pathology of IgG4-related disease" (2,616).

Most cited papers
#PaperReleasedCitations
1 High Serum IgG4 Concentrations in Patients with Sclerosing Pancreatitis Hideaki Hamano, Shigeyuki Kawa, Akira C. Horiuchi et al. · New England Journal of Medicine Open access 8 Mar 2001 2,725
2 IgG4-Related Disease John H. Stone, Yoh Zen, Vikram Deshpande · New England Journal of Medicine 8 Feb 2012 2,629
3 Consensus statement on the pathology of IgG4-related disease Vikram Deshpande et al. · Modern Pathology Open access 18 May 2012 2,616
4 Simplified criteria for the diagnosis of autoimmune hepatitis† Elke M. Hennes, Mikio Zeniya, Albert J. Czaja et al. · Hepatology Open access 19 Mar 2008 1,907
5 A Step-up Approach or Open Necrosectomy for Necrotizing Pancreatitis Hjalmar C. van Santvoort et al. · New England Journal of Medicine Open access 21 Apr 2010 1,726
All 97 most cited papers, with filters and sorting

Where is IgG4-Related and Inflammatory Diseases research done?

The largest centres of IgG4-Related and Inflammatory Diseases research in 2022-now are Beijing (China), Tokyo (Japan), Shanghai (China) and New Delhi (India).

Largest cities, 2022-now

  1. 1 BeijingChina 133 works
  2. 2 TokyoJapan 80 works
  3. 3 ShanghaiChina 47 works
  4. 4 New DelhiIndia 37 works
  5. 5 ChengduChina 33 works
  6. 6 ParisFrance 32 works
  7. 7 LondonUnited Kingdom 32 works
  8. 8 SeoulSouth Korea 31 works
  9. 9 GuangzhouChina 31 works
  10. 10 MadridSpain 31 works
See IgG4-Related and Inflammatory Diseases on the map

Where is the best place to study IgG4-Related and Inflammatory Diseases?

Among universities, judged by research, Harvard University, Capital Medical University and Chinese Academy of Medical Sciences & Peking Union Medical College score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 15.46%fractional works in this field (log) →share of work in the world top 10% →Harvard UniversityChinese Academy of M…Peking UniversityCapital Medical Univ…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 88.225.4%3.8×37 +6.3%
2Capital Medical UniversityChina 66.113.3%11.1×36 +138.8%
3Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 60.518.4%7.0×22 +9.2%
4Peking UniversityChina 58.213.6%4.0×25 +57.3%
5Tsinghua UniversityChina 52.115.8%2.9×20 +5.3%
6Huazhong University of Science and TechnologyChina 50.522.4%2.4×13 +33.2%
7All India Institute of Medical SciencesIndia 50.44.5%8.1×27 +45.4%
8Sichuan UniversityChina 50.112.2%3.4×23 +53.6%
9Johns Hopkins UniversityUnited States 47.87.2%2.7×13 +31.6%
10Université Paris CitéFrance 45.521.8%4.2×10 -13.7%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in IgG4-Related and Inflammatory Diseases, country by country

Is IgG4-Related and Inflammatory Diseases research growing?

Output in 2022-2025 was 16% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are IgG4-Related and Inflammatory Diseases.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is IgG4-Related and Inflammatory Diseases as a percentage of every work published that year, 0.012% in 2024.

still counting0.0050%0.010%0.015%IgG4-Related and Inflammatory Diseases0.015% in 202519801990200020102020

Fractional works of IgG4-Related and Inflammatory Diseases over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%IgG4-Related and Inflammatory Diseases10.1% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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