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Company · Seattle · United States

Acucela (United States)

acucela.com/index.htmlROR OpenAlex
Research works
33
▼ 96% vs 2018-21
Citations
485
14.6 per fractional work
Top-10% rate
8.0%
all institutions 10.0%
Open access
27%
world 40%
International
6%
world 18%
Acucela (United States)

Not ranked overall: Acucela (United States) is under the volume floor below which a citation excellence rate is noise. Not ranked is not the same as ranked last.

Which fields of science does Acucela (United States) work in?

In all years, 46% of research at Acucela (United States) is in Life Sciences, 43% in Health Sciences. Its largest fields are Medicine (43%), Biochemistry, Genetics and Molecular Biology (29%), Neuroscience (14%). It does 2.3× the world's share of Life Sciences.

Life Sciences: 15 fractional works · 46.0% of its workBiochemistry, Genetics and Molecular Biology: 10 fractional works · 29.1% of its workMolecular Biology: 8 fractional works · 25.3% of its workBiochemistry: 1 fractional works · 2.0% of its workCell Biology: 0 fractional works · 1.0% of its workGenetics: 0 fractional works · 0.5% of its workPhysiology: 0 fractional works · 0.3% of its workNeuroscience: 5 fractional works · 14.1% of its workCellular and Molecular Neuroscience: 2 fractional works · 7.5% of its workNeurology: 2 fractional works · 6.0% of its workEndocrine and Autonomic Systems: 0 fractional works · 0.5% of its workAgricultural and Biological Sciences: 0 fractional works · 1.3% of its workPlant Science: 0 fractional works · 0.6% of its workFood Science: 0 fractional works · 0.5% of its workSoil Science: 0 fractional works · 0.2% of its workImmunology and Microbiology: 0 fractional works · 0.8% of its workImmunology: 0 fractional works · 0.5% of its workVirology: 0 fractional works · 0.3% of its workPharmacology, Toxicology and Pharmaceutics: 0 fractional works · 0.7% of its workPharmacology: 0 fractional works · 0.5% of its workPharmaceutical Science: 0 fractional works · 0.2% of its workHealth Sciences: 14 fractional works · 42.8% of its workMedicine: 14 fractional works · 42.8% of its workOphthalmology: 8 fractional works · 25.5% of its workRadiology, Nuclear Medicine and Imaging: 1 fractional works · 3.6% of its workPhysiology: 1 fractional works · 3.5% of its workCardiology and Cardiovascular Medicine: 1 fractional works · 1.7% of its workBiochemistry: 1 fractional works · 1.5% of its workPharmacology: 0 fractional works · 1.5% of its workPulmonary and Respiratory Medicine: 0 fractional works · 1.3% of its workOncology: 0 fractional works · 1.0% of its workRheumatology: 0 fractional works · 1.0% of its workEndocrinology, Diabetes and Metabolism: 0 fractional works · 0.8% of its workInfectious Diseases: 0 fractional works · 0.3% of its workNeurology: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.6% of its workPhysical Sciences: 3 fractional works · 8.8% of its workChemical Engineering: 1 fractional works · 3.0% of its workBioengineering: 1 fractional works · 3.0% of its workEnvironmental Science: 1 fractional works · 2.0% of its workGlobal and Planetary Change: 0 fractional works · 1.0% of its workHealth, Toxicology and Mutagenesis: 0 fractional works · 0.7% of its workManagement, Monitoring, Policy and Law: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.0% of its workChemistry: 1 fractional works · 2.0% of its workOrganic Chemistry: 0 fractional works · 1.5% of its workAnalytical Chemistry: 0 fractional works · 0.5% of its workMaterials Science: 0 fractional works · 1.3% of its workMaterials Chemistry: 0 fractional works · 1.3% of its workEngineering: 0 fractional works · 0.2% of its workMechanical Engineering: 0 fractional works · 0.2% of its workMathematics: 0 fractional works · 0.2% of its workStatistics and Probability: 0 fractional works · 0.2% of its workSocial Sciences: 1 fractional works · 2.4% of its workPsychology: 1 fractional works · 2.0% of its workSocial Psychology: 1 fractional works · 2.0% of its workBusiness, Management and Accounting: 0 fractional works · 0.4% of its workMarketing: 0 fractional works · 0.4% of its workALL ITS WORKAcucela (UnitedStates)33fractional works, all years
Life Sciences46%Physical Sciences9%Health Sciences43%Social Sciences2%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in all years. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 14 fields, with their numbers
    1. Biochemistry, Genetics and Molecular Biology1029.1%
    2. Neuroscience514.1%
    3. Agricultural and Biological Sciences01.3%
    4. Immunology and Microbiology00.8%
    5. Pharmacology, Toxicology and Pharmaceutics00.7%
    1. Medicine1442.8%
    1. Chemical Engineering13.0%
    2. Environmental Science12.0%
    3. Chemistry12.0%
    4. Materials Science01.3%
    5. Engineering00.2%
    6. Mathematics00.2%
    1. Psychology12.0%
    2. Business, Management and Accounting00.4%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Who are the top researchers at Acucela (United States)?

Ranked on the quality score, Claes Båvik, John M Koester and Ahmad B. Fawzi lead among researchers whose main affiliation is Acucela (United States).

  1. 1 Claes Båvik United States · #1,201,716 worldwide 1.8k citations · 23 works
  2. 2 John M Koester United States · #1,562,217 worldwide 399 citations · 15 works
  3. 3 Ahmad B. Fawzi United States · #2,683,210 worldwide 3k citations · 76 works
  4. 4 Ryo Kubota United States · #2,970,140 worldwide 3.1k citations · 147 works
All ranked researchers at Acucela (United States)

What are the most cited papers from Acucela (United States)?

The most cited paper from Acucela (United States) is "Emixustat Hydrochloride for Geographic Atrophy Secondary to Age-Related Macular Degeneration" (Philip J. Rosenfeld, Pravin U. Dugel, Frank Gerhard Holz et al., 2018), with 124 citations. Next come "SAFETY AND EFFECT ON ROD FUNCTION OF ACU-4429, A NOVEL SMALL-MOLECULE VISUAL CYCLE MODULATOR" (97) and "Effects of Potent Inhibitors of the Retinoid Cycle on Visual Function and Photoreceptor Protection from Light Damage in Mice" (80).

Most cited papers
#PaperReleasedCitations
1 Emixustat Hydrochloride for Geographic Atrophy Secondary to Age-Related Macular Degeneration Philip J. Rosenfeld, Pravin U. Dugel, Frank Gerhard Holz et al. · Ophthalmology Open access 30 Apr 2018 124
2 SAFETY AND EFFECT ON ROD FUNCTION OF ACU-4429, A NOVEL SMALL-MOLECULE VISUAL CYCLE MODULATOR Ryo Kubota, Nancy L. Boman, Robert David et al. · Retina 26 Apr 2011 97
3 Effects of Potent Inhibitors of the Retinoid Cycle on Visual Function and Photoreceptor Protection from Light Damage in Mice Akiko Maeda, Tadao Maeda, Marcin Golczak et al. · Molecular Pharmacology Open access 12 Jul 2006 80
4 Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity Claes Båvik, Susan Henry, Yan Zhang et al. · PLoS ONE Open access 13 May 2015 74
5 PHASE 1, DOSE-RANGING STUDY OF EMIXUSTAT HYDROCHLORIDE (ACU-4429), A NOVEL VISUAL CYCLE MODULATOR, IN HEALTHY VOLUNTEERS Ryo Kubota, Suliman Al‐Fayoumi, Suresh Mallikaarjun et al. · Retina 20 Sep 2013 73
All 44 most cited papers, with filters and sorting

Which keywords describe research at Acucela (United States)?

By fractional works in all years, weighted toward what it does more of than the world: Oxidative Stress, Macular Degeneration, Inflammation, Gene Therapy, Retinitis Pigmentosa, Diabetic Retinopathy, Vascular Endothelial Growth Factor and Intravitreal Injection.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in all years in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Oxidative Stress10▲ 17×14 topics
  2. Macular Degeneration9▲ 215×3 topics
  3. Inflammation6▲ 7.5×6 topics
  4. Gene Therapy4▲ 51×1 topic
  5. Retinitis Pigmentosa4▲ 328×1 topic
  6. Diabetic Retinopathy4▲ 159×2 topics
  7. Vascular Endothelial Growth Factor4▲ 128×2 topics
  8. Choroidal Thickness4▲ 233×1 topic
  9. Intravitreal Injection4▲ 173×2 topics
  10. Retinal Pigment Epithelium4▲ 233×1 topic
  11. Antioxidant3▲ 12×5 topics
  12. Optical Coherence Tomography3▲ 68×2 topics
  13. Memory Impairment2▲ 216×2 topics
  14. Neuroprotective Effects2▲ 55×2 topics
  15. Cerebral Hypoperfusion2▲ 212×1 topic
  16. Glaucoma2▲ 37×3 topics
  17. Vascular Cognitive Impairment2▲ 212×1 topic
  18. Retinopathy2▲ 264×2 topics
  19. Neurodegeneration2▲ 15×3 topics
  20. Optic Nerve2▲ 49×2 topics
  21. Risk Factors2▲ 4.7×2 topics
  22. COVID-191▲ 6.5×1 topic
  23. Ocular Findings1▲ 168×1 topic
  24. Acute Promyelocytic Leukemia1▲ 133×1 topic
  25. Biosensors1▲ 7.0×2 topics
  26. Chloroquine1▲ 547×1 topic
  27. Hydroxychloroquine1▲ 547×1 topic
  28. Metabolic Engineering1▲ 31×2 topics
  29. Neuroprotection1▲ 10×3 topics
  30. OCT Imaging1▲ 125×2 topics
  31. Retinal Ganglion Cells1▲ 29×2 topics
  32. Retinoic Acid1▲ 133×1 topic
  33. Aging1▲ 6.7×2 topics
  34. Reactive Oxygen Species1▲ 7.1×3 topics
  35. Intraocular Pressure1▲ 32×1 topic
  36. Ocular Hypertension1▲ 51×1 topic
  37. Channelrhodopsin1▲ 54×1 topic
  38. Electrode Arrays1▲ 53×1 topic
  39. Ion-Selective Electrodes1▲ 30×1 topic
  40. Neural Stimulation1▲ 53×1 topic

Which research topics does Acucela (United States) publish most on?

By volume in 2022-now: Environmental Sustainability in Business and Environmental Sustainability and Education.

  1. 1 Environmental Sustainability in Business Marketing 0 works
  2. 2 Environmental Sustainability and Education Management, Monitoring, Policy and Law 0 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available27.2%not open72.8%

World: 40% of research is openly available.

with international co-authors5.9%domestic only94.1%

World: 18% is written across borders.

How has Acucela (United States)'s research output changed?

Output in 2022-2025 was 96% lower than in 2018-2021.

201020152020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Acucela (United States) as a percentage of every work published that year, 0.000037% in 2020.

0.00010%0.00020%0.00030%Acucela (United States)0.0000045% in 202420102020

Fractional works of Acucela (United States) over all fractional works that year. How the balance of science has shifted.

Other research institutions in Seattle

All research institutions in Seattle

Research measures only: rankings here say nothing about teaching, admissions or student experience. Comparable institutions and collaboration partners have tabs of their own, above.

Discussion

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