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Company · Sioux Falls · United States

SynZyme Technologies (United States)

synzyme.com/main_page.htmlROR OpenAlex
World rank, all time
#30,143
of 34,923
Rank in United States
#6,355
of 7,310
Research works
157
▲ 62% vs 2018-21
Citations
6.7k
42.5 per fractional work
Top-10% rate
7.9%
all institutions 10.0%
vs its own fields
1.05×
1.00× is exactly expected
Open access
36%
world 40%
International
21%
world 18%
SynZyme Technologies (United States)

Which fields of science does SynZyme Technologies (United States) work in?

In all years, 42% of research at SynZyme Technologies (United States) is in Life Sciences, 41% in Health Sciences. Its largest fields are Medicine (39%), Biochemistry, Genetics and Molecular Biology (32%), Immunology and Microbiology (4%). It does 2.6× the world's share of Life Sciences.

Life Sciences: 67 fractional works · 42.3% of its workBiochemistry, Genetics and Molecular Biology: 50 fractional works · 31.8% of its workMolecular Biology: 33 fractional works · 21.1% of its workGenetics: 8 fractional works · 5.0% of its workCell Biology: 3 fractional works · 2.0% of its workBiotechnology: 2 fractional works · 1.4% of its workCancer Research: 2 fractional works · 1.0% of its workBiophysics: 1 fractional works · 0.6% of its workPhysiology: 0 fractional works · 0.3% of its workSmaller subfields together: 1 fractional works · 0.4% of its workImmunology and Microbiology: 6 fractional works · 3.9% of its workImmunology: 6 fractional works · 3.5% of its workMicrobiology: 1 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.0% of its workAgricultural and Biological Sciences: 6 fractional works · 3.6% of its workPlant Science: 2 fractional works · 1.5% of its workAnimal Science and Zoology: 2 fractional works · 1.3% of its workFood Science: 1 fractional works · 0.6% of its workSmaller subfields together: 0 fractional works · 0.2% of its workNeuroscience: 3 fractional works · 2.2% of its workNeurology: 2 fractional works · 1.1% of its workCellular and Molecular Neuroscience: 1 fractional works · 0.4% of its workEndocrine and Autonomic Systems: 1 fractional works · 0.3% of its workCognitive Neuroscience: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.1% of its workPharmacology, Toxicology and Pharmaceutics: 1 fractional works · 0.7% of its workPharmacology: 1 fractional works · 0.4% of its workToxicology: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.0% of its workHealth Sciences: 64 fractional works · 40.5% of its workMedicine: 61 fractional works · 39.0% of its workPhysiology: 10 fractional works · 6.5% of its workSurgery: 5 fractional works · 3.3% of its workOncology: 5 fractional works · 3.0% of its workPublic Health, Environmental and Occupational Health: 3 fractional works · 2.1% of its workGenetics: 3 fractional works · 2.1% of its workPathology and Forensic Medicine: 3 fractional works · 2.0% of its workHematology: 3 fractional works · 1.9% of its workEpidemiology: 3 fractional works · 1.9% of its workPulmonary and Respiratory Medicine: 3 fractional works · 1.8% of its workRheumatology: 3 fractional works · 1.8% of its workNeurology: 2 fractional works · 1.5% of its workNephrology: 2 fractional works · 1.4% of its workInfectious Diseases: 2 fractional works · 1.1% of its workRadiology, Nuclear Medicine and Imaging: 2 fractional works · 1.1% of its workEndocrinology, Diabetes and Metabolism: 2 fractional works · 1.1% of its workOrthopedics and Sports Medicine: 1 fractional works · 0.9% of its workPediatrics, Perinatology and Child Health: 1 fractional works · 0.9% of its workPharmacology: 1 fractional works · 0.7% of its workImmunology and Allergy: 1 fractional works · 0.5% of its workCardiology and Cardiovascular Medicine: 1 fractional works · 0.5% of its workDermatology: 1 fractional works · 0.4% of its workEmergency Medicine: 1 fractional works · 0.4% of its workComplementary and alternative medicine: 1 fractional works · 0.3% of its workUrology: 1 fractional works · 0.3% of its workOphthalmology: 0 fractional works · 0.3% of its workRehabilitation: 0 fractional works · 0.3% of its workOtorhinolaryngology: 0 fractional works · 0.2% of its workSmaller subfields together: 1 fractional works · 0.7% of its workNursing: 2 fractional works · 1.1% of its workNutrition and Dietetics: 2 fractional works · 1.1% of its workHealth Professions: 0 fractional works · 0.2% of its workVeterinary: 0 fractional works · 0.1% of its workPhysical Sciences: 17 fractional works · 10.9% of its workChemistry: 5 fractional works · 3.1% of its workOrganic Chemistry: 4 fractional works · 2.7% of its workSmaller subfields together: 1 fractional works · 0.5% of its workEngineering: 4 fractional works · 2.7% of its workBiomedical Engineering: 2 fractional works · 1.4% of its workControl and Systems Engineering: 1 fractional works · 0.6% of its workMechanical Engineering: 1 fractional works · 0.4% of its workComputational Mechanics: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.2% of its workEnvironmental Science: 3 fractional works · 2.0% of its workEcology: 1 fractional works · 0.4% of its workEnvironmental Engineering: 1 fractional works · 0.4% of its workPollution: 1 fractional works · 0.4% of its workWater Science and Technology: 0 fractional works · 0.3% of its workNature and Landscape Conservation: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.2% of its workMaterials Science: 3 fractional works · 1.9% of its workMaterials Chemistry: 2 fractional works · 1.0% of its workBiomaterials: 1 fractional works · 0.8% of its workSmaller subfields together: 0 fractional works · 0.0% of its workComputer Science: 1 fractional works · 0.8% of its workComputer Vision and Pattern Recognition: 1 fractional works · 0.6% of its workSmaller subfields together: 0 fractional works · 0.1% of its workPhysics and Astronomy: 0 fractional works · 0.2% of its workAstronomy and Astrophysics: 0 fractional works · 0.2% of its workMathematics: 0 fractional works · 0.2% of its workSocial Sciences: 10 fractional works · 6.3% of its workSocial Sciences: 5 fractional works · 3.2% of its workEducation: 1 fractional works · 0.7% of its workLinguistics and Language: 1 fractional works · 0.6% of its workAnthropology: 1 fractional works · 0.4% of its workSafety Research: 1 fractional works · 0.4% of its workSociology and Political Science: 0 fractional works · 0.3% of its workPolitical Science and International Relations: 0 fractional works · 0.3% of its workCultural Studies: 0 fractional works · 0.2% of its workGeography, Planning and Development: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.0% of its workArts and Humanities: 2 fractional works · 1.1% of its workPhilosophy: 1 fractional works · 0.6% of its workReligious studies: 1 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.1% of its workEconomics, Econometrics and Finance: 2 fractional works · 1.0% of its workEconomics and Econometrics: 2 fractional works · 1.0% of its workBusiness, Management and Accounting: 1 fractional works · 0.4% of its workOrganizational Behavior and Human Resource Management: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.2% of its workDecision Sciences: 0 fractional works · 0.3% of its workInformation Systems and Management: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.1% of its workPsychology: 0 fractional works · 0.3% of its workApplied Psychology: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.1% of its workALL ITS WORKSynZymeTechnologies…157fractional works, all years
Life Sciences42%Physical Sciences11%Health Sciences41%Social Sciences6%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in all years. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 22 fields, with their numbers
    1. Biochemistry, Genetics and Molecular Biology5031.8%
    2. Immunology and Microbiology63.9%
    3. Agricultural and Biological Sciences63.6%
    4. Neuroscience32.2%
    5. Pharmacology, Toxicology and Pharmaceutics10.7%
    1. Medicine6139.0%
    2. Nursing21.1%
    3. Health Professions00.2%
    4. Veterinary00.1%
    1. Chemistry53.1%
    2. Engineering42.7%
    3. Environmental Science32.0%
    4. Materials Science31.9%
    5. Computer Science10.8%
    6. Physics and Astronomy00.2%
    7. Mathematics00.2%
    1. Social Sciences53.2%
    2. Arts and Humanities21.1%
    3. Economics, Econometrics and Finance21.0%
    4. Business, Management and Accounting10.4%
    5. Decision Sciences00.3%
    6. Psychology00.3%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 4.12× its world share, 2 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 7.55× its world share, 5 worksBiochemistry, Geneti…Immunology and Microbiology: 1.77× its world share, 0 worksImmunology and Micro…Chemistry: 0.91× its world share, 0 worksChemistryComputer Science: 0.06× its world share, 0 worksComputer ScienceEngineering: 0.06× its world share, 0 worksEngineeringEnvironmental Science: 0.29× its world share, 0 worksEnvironmental ScienceMaterials Science: 0.50× its world share, 0 worksMaterials ScienceHealth Professions: 0.99× its world share, 0 worksHealth ProfessionsMedicine: 0.66× its world share, 2 worksMedicineVeterinary: 10.48× its world share, 0 worksVeterinaryArts and Humanities: 0.99× its world share, 0 worksArts and HumanitiesBusiness, Management and Accounting: 0.29× its world share, 0 worksBusiness, Management…Decision Sciences: 1.47× its world share, 0 worksDecision SciencesPsychology: 0.93× its world share, 0 worksPsychologySocial Sciences: 0.60× its world share, 1 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Veterinary, 10.5×. Every wedge is a field page.

All 16 fields, with their numbers
  1. Veterinary10.48×0 works
  2. Biochemistry, Genetics and Molecular Biology7.55×5 works
  3. Agricultural and Biological Sciences4.12×2 works
  4. Immunology and Microbiology1.77×0 works
  5. Decision Sciences1.47×0 works
  6. Health Professions0.99×0 works
  7. Arts and Humanities0.99×0 works
  8. Psychology0.93×0 works
  9. Chemistry0.91×0 works
  10. Medicine0.66×2 works
  11. Social Sciences0.60×1 works
  12. Materials Science0.50×0 works
  13. Environmental Science0.29×0 works
  14. Business, Management and Accounting0.29×0 works
  15. Computer Science0.06×0 works
  16. Engineering0.06×0 works

Who are the top researchers at SynZyme Technologies (United States)?

Ranked on the quality score, Malgorzata Przybylska, Tim Edmunds and Frank J. Riske lead among researchers whose main affiliation is SynZyme Technologies (United States).

  1. 1 Malgorzata Przybylska United States · #1,511,335 worldwide 1.7k citations · 26 works
  2. 2 Tim Edmunds United States · #1,674,980 worldwide 2.3k citations · 52 works
  3. 3 Frank J. Riske United States · #1,833,329 worldwide 1.1k citations · 23 works
  4. 4 Leslie S. Kurtzberg United States · #2,561,040 worldwide 937 citations · 35 works
  5. 5 Charles E. Trimble United States · #2,875,778 worldwide 278 citations · 21 works
  6. 6 Carleton J. C. Hsia United States · #6,123,985 worldwide 1k citations · 66 works
All ranked researchers at SynZyme Technologies (United States)

What are the most cited papers from SynZyme Technologies (United States)?

The most cited paper from SynZyme Technologies (United States) is "Production of goats by somatic cell nuclear transfer" (Alexander B. Baguisi, Esmail Behboodi, David T. Melican et al., 1999), with 1,005 citations. Next come "LIMP-2 Is a Receptor for Lysosomal Mannose-6-Phosphate-Independent Targeting of β-Glucocerebrosidase" (538) and "Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte–mediated Tumor Immunosurveillance" (538).

Most cited papers
#PaperReleasedCitations
1 Production of goats by somatic cell nuclear transfer Alexander B. Baguisi, Esmail Behboodi, David T. Melican et al. · Nature Biotechnology May 1999 1,005
2 LIMP-2 Is a Receptor for Lysosomal Mannose-6-Phosphate-Independent Targeting of β-Glucocerebrosidase David Reczek, Michael Schwake, J Oltmann Schröder et al. · Cell Open access Nov 2007 538
3 Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte–mediated Tumor Immunosurveillance Masaki Terabe, So Matsui, Jong-Myun Park et al. · The Journal of Experimental Medicine Open access Dec 2003 538
4 Globotriaosylceramide accumulation in the Fabry kidney is cleared from multiple cell types after enzyme replacement therapy Beth L. Thurberg, Helmut G. Rennke, Robert B. Colvin et al. · Kidney International Open access Dec 2002 335
5 CNS expression of glucocerebrosidase corrects α-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy S. Pablo Sardi, Jennifer Leigh Clarke, Cathrine Kinnecom et al. · Proceedings of the National Academy of Sciences Open access 5 Jul 2011 324
All 60 most cited papers, with filters and sorting

Which keywords describe research at SynZyme Technologies (United States)?

By fractional works in all years, weighted toward what it does more of than the world: Parkinson's Disease, Enzyme Replacement Therapy, Lysosomal Storage Disorders, Gene Therapy, Inflammation, Cancer, Angiogenesis and Cancer Progression.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in all years in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Inflammation11▲ 2.9×31 topics
  2. Cancer9▲ 3.9×22 topics
  3. Parkinson's Disease8▲ 23×3 topics
  4. Enzyme Replacement Therapy8▲ 184×1 topic
  5. Lysosomal Storage Disorders8▲ 254×1 topic
  6. Epidemiology7◆ 1.14×20 topics
  7. Gene Therapy7▲ 16×5 topics
  8. Oxidative Stress6▲ 2.2×17 topics
  9. Angiogenesis5▲ 7.3×10 topics
  10. Cancer Progression4▲ 12×5 topics
  11. Metabolism4▲ 4.2×10 topics
  12. Genomic Integration4▲ 26×2 topics
  13. Glycosylation4▲ 12×3 topics
  14. Neurodegeneration4▲ 8.5×8 topics
  15. Cancer Therapy4▲ 4.1×12 topics
  16. Chemotherapy4▲ 3.3×8 topics
  17. Apoptosis4▲ 5.9×9 topics
  18. AAV3▲ 33×1 topic
  19. Viral Vectors3▲ 33×1 topic
  20. Genetic Mutations3▲ 3.9×7 topics
  21. Infection3▲ 7.3×5 topics
  22. Glycosidase Inhibitors3▲ 39×1 topic
  23. Metastasis3▲ 5.8×7 topics
  24. Oligosaccharide Synthesis3▲ 39×1 topic
  25. Neuroprotection3▲ 4.9×6 topics
  26. Prognostic Factors3▲ 4.0×4 topics
  27. Innate Immunity3▲ 5.0×8 topics
  28. Pathophysiology3▲ 6.1×3 topics
  29. Epigenetic Regulation2▲ 7.2×6 topics
  30. Gene Expression Regulation2▲ 13×2 topics
  31. RNA Interference2▲ 14×1 topic
  32. siRNA Delivery2▲ 20×1 topic
  33. Biopharmaceutical Production2▲ 19×2 topics
  34. Tumor Suppression2▲ 13×3 topics
  35. Prenatal Diagnosis2▲ 7.8×3 topics
  36. Biopharmaceuticals2▲ 19×3 topics
  37. Monoclonal Antibodies2▲ 9.1×3 topics
  38. Pericytes2▲ 27×2 topics
  39. Therapeutics2▲ 9.6×2 topics
  40. m6A-seq2▲ 16×1 topic

Which research topics does SynZyme Technologies (United States) publish most on?

By volume in 2022-now: CRISPR and Genetic Engineering, Animal Nutrition and Physiology, Rabbits: Nutrition, Reproduction, Health and Probiotics and Fermented Foods.

CRISPR and Genetic Engin…1CRISPR and Genetic Engineering: 1 fractional worksAnimal Nutrition and Physiology: 1 fractional worksRabbits: Nutrition, Repr…0Rabbits: Nutrition, Reproduction, Health: 0 fractional worksProbiotics and Fermented…0Probiotics and Fermented Foods: 0 fractional worksRNA modifications and cancer: 0 fractional worksCatholicism, Bioethics, Media, Education: 0 fractional worksBacillus and Francisella…0Bacillus and Francisella bacterial research: 0 fractional worksTheology and Canon Law S…0Theology and Canon Law Studies: 0 fractional worksBiopolymer Synthesis and…0Biopolymer Synthesis and Applications: 0 fractional worksSinusitis and nasal cond…0Sinusitis and nasal conditions: 0 fractional works
Molecular BiologyAnimal Science and ZoologyFood ScienceSafety Research2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 CRISPR and Genetic Engineering Molecular Biology 1 works
  2. 2 Animal Nutrition and Physiology Animal Science and Zoology 1 works
  3. 3 Rabbits: Nutrition, Reproduction, Health Animal Science and Zoology 0 works
  4. 4 Probiotics and Fermented Foods Food Science 0 works
  5. 5 RNA modifications and cancer Molecular Biology 0 works
  6. 6 Catholicism, Bioethics, Media, Education Safety Research 0 works
  7. 7 Bacillus and Francisella bacterial research Molecular Biology 0 works
  8. 8 Theology and Canon Law Studies Religious studies 0 works
  9. 9 Biopolymer Synthesis and Applications Molecular Biology 0 works
  10. 10 Sinusitis and nasal conditions Otorhinolaryngology 0 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available36.1%not open63.9%

World: 40% of research is openly available.

with international co-authors20.9%domestic only79.1%

World: 18% is written across borders.

How has SynZyme Technologies (United States)'s research output changed?

Output in 2022-2025 was 62% higher than in 2018-2021.

still counting200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is SynZyme Technologies (United States) as a percentage of every work published that year, 0.000068% in 2024.

still counting0.00020%0.00040%0.00060%SynZyme Technologies (United States)0.000054% in 2025200020102020

Fractional works of SynZyme Technologies (United States) over all fractional works that year. How the balance of science has shifted.

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