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Topic · Molecular Biology

Sphingolipid Metabolism and Signaling

Sphingolipid Metabolism and Signaling is a research topic within Molecular Biology. Science Explorer counts 15k research works in it since 1953. 22.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of sphingolipids, including sphingosine-1-phosphate and ceramide, in signaling and metabolism, with implications for health and disease such as lymphocyte egress, insulin resistance, cancer, and apoptosis.

  • Sphingolipids
  • Sphingosine-1-Phosphate
  • Ceramide
  • Lysophospholipids
  • Sphingosine Kinase
  • FTY720
  • Lymphocyte Egress
  • Insulin Resistance
  • Cancer
  • Apoptosis
Research works
15k
fractional, since 1953
In the world top 10%
3.2k
per year above
Top-10% rate
22.0%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+10%
the tick is no change

Which countries lead Sphingolipid Metabolism and Signaling research?

By volume, China and the United States publish the most (642 and 439 works in 2022–2025).

By volume, 2022–2025

  1. 1 China 642 works
  2. 2 United States 439 works
  3. 3 Japan 147 works
  4. 4 Germany 116 works
  5. 5 Italy 73 works
  6. 6 India 70 works
  7. 7 South Korea 66 works
  8. 8 France 57 works
  9. 9 United Kingdom 51 works
  10. 10 Spain 50 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 37.6%United States: 25.7%Japan: 8.6%Germany: 6.8%6 others listed: 21.4%38%largest
China642 · 37.6%United States439 · 25.7%Japan147 · 8.6%Germany116 · 6.8%6 others listed367 · 21.4%

Shares of the rows listed above, not of the whole node.

Which institutions lead Sphingolipid Metabolism and Signaling research?

By volume in 2022–2025, Virginia Commonwealth University publishes the most Sphingolipid Metabolism and Signaling research, followed by Chinese Academy of Medical Sciences & Peking Union Medical College and Nanjing University of Chinese Medicine.

By volume, 2022–2025

  1. 1 Virginia Commonwealth UniversityUnited States 12 works
  2. 2 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 11 works
  3. 3 Nanjing University of Chinese MedicineChina 10 works
  4. 4 The University of TokyoJapan 9 works
  5. 5 Medical University of BiałystokPoland 8 works
  6. 6 Shanghai Jiao Tong UniversityChina 8 works
  7. 7 Washington University in St. LouisUnited States 7 works
  8. 8 Sun Yat-sen UniversityChina 7 works
  9. 9 Capital Medical UniversityChina 7 works
  10. 10 University of UtahUnited States 7 works

Who are the leading researchers in Sphingolipid Metabolism and Signaling?

The most-cited researchers publishing on Sphingolipid Metabolism and Signaling include Gordon B. Mills, Joseph L. Goldstein and Michael S. Brown.

  1. 1 Gordon B. Mills United States 3.7k citations
  2. 2 Joseph L. Goldstein United States 2.5k citations
  3. 3 Michael S. Brown United States 2.5k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Sphingolipid Metabolism and Signaling research done?

The largest centres of Sphingolipid Metabolism and Signaling research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Tokyo (Japan).

Largest cities, 2022–2025

  1. 1 Beijing China 81 works
  2. 2 Shanghai China 54 works
  3. 3 Guangzhou China 45 works
  4. 4 Tokyo Japan 41 works
  5. 5 Nanjing China 37 works
  6. 6 Wuhan China 27 works
  7. 7 Paris France 25 works
  8. 8 Seoul South Korea 24 works
  9. 9 New York United States 23 works
  10. 10 Hangzhou China 21 works
See Sphingolipid Metabolism and Signaling on the map

Where is the best place to study Sphingolipid Metabolism and Signaling?

Among universities, judged by research, Nanjing University of Chinese Medicine, Virginia Commonwealth University and Chinese Academy of Medical Sciences & Peking Union Medical College score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 25.275%fractional works in this node (log) →share in the world top 10% →Nanjing University of Chinese Medicine: 10, 36.2%Virginia Commonwealth University: 12, 23.3%Chinese Academy of Medical Sciences & Peking Union Medical College: 11, 29.1%The University of Tokyo: 9, 12.5%Nanjing University o…Chinese Academy of M…Virginia Commonwealt…The University of To…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Nanjing University of Chinese MedicineChina 68.136.2%18.7×10 —
2 Virginia Commonwealth UniversityUnited States 67.423.3%17.8×12 -0.2%
3 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 61.529.1%5.3×11 +69.7%
4 The University of TokyoJapan 10.012.5%3.4×9 -17.2%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Sphingolipid Metabolism and Signaling research growing?

Output in 2018–2022 was 10% higher than in 2013–2017, peaking in 2020. The fastest-growing topics are Sphingolipid Metabolism and Signaling.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.