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Topic · Molecular Biology

bioluminescence and chemiluminescence research

bioluminescence and chemiluminescence research is a research topic within Molecular Biology. Science Explorer counts 23k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the advances in bioluminescence imaging, reporter gene systems, and biosensors. It covers topics such as the use of luciferase and fluorescent proteins for in vivo imaging, microbial biosensors for environmental monitoring, and the application of pyrosequencing in genetic analysis.

  • Bioluminescence
  • Reporter Genes
  • Luciferase
  • Imaging
  • Biosensors
  • Pyrosequencing
  • Gene Expression
  • Environmental Monitoring
  • Fluorescent Protein
  • Microbial Biosensors
Research works
23k
fractional, since 1950
In the world top 10%
2.3k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+7%
the tick is no change
Largest producer
China
29% of the 10 largest, 2022-now
bioluminescence and chemiluminescence research

Which countries lead bioluminescence and chemiluminescence research research?

By volume, China and the United States publish the most (552 and 474 works in 2022-now).

By volume, 2022-now

  1. 1 China 552 works
  2. 2 United States 474 works
  3. 3 Russia 202 works
  4. 4 India 164 works
  5. 5 Japan 161 works
  6. 6 Germany 112 works
  7. 7 France 70 works
  8. 8 Brazil 69 works
  9. 9 Italy 60 works
  10. 10 United Kingdom 59 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 28.7%United States: 24.7%Russia: 10.5%India: 8.5%6 others listed: 27.6%29%largest
China552 · 28.7%United States474 · 24.7%Russia202 · 10.5%India164 · 8.5%6 others listed531 · 27.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead bioluminescence and chemiluminescence research research?

By volume in 2022-now, Russian Academy of Sciences publishes the most bioluminescence and chemiluminescence research research, followed by Chinese Academy of Sciences and Centre National de la Recherche Scientifique.

By volume, 2022-now

  1. 1 Russian Academy of SciencesRussia 79 works
  2. 2 Chinese Academy of SciencesChina 31 works
  3. 3 Centre National de la Recherche ScientifiqueFrance 27 works
  4. 4 Lomonosov Moscow State UniversityRussia 17 works
  5. 5 Promega (United States)United States 14 works
  6. 6 The University of TokyoJapan 11 works
  7. 7 Universidade de São PauloBrazil 11 works
  8. 8 Harvard UniversityUnited States 10 works
  9. 9 National Institutes of HealthUnited States 10 works
  10. 10 National Institute of Advanced Industrial Science and TechnologyJapan 9 works

Who are the leading researchers in bioluminescence and chemiluminescence research?

The most-cited researchers publishing on bioluminescence and chemiluminescence research include Michaël Grätzel, Wei Huang and Gordon Brent Mills.

  1. 1 Michaël Grätzel Switzerland 458k citations
  2. 2 Wei Huang China 267k citations
  3. 3 Gordon Brent Mills United States 265k citations
  4. 4 Charles M. Perou United States 263k citations
  5. 5 Ben Zhong Tang China 261k citations
  6. 6 Hans C. Clevers Netherlands 260k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in bioluminescence and chemiluminescence research?

The most cited paper in bioluminescence and chemiluminescence research is "A new and rapid colorimetric determination of acetylcholinesterase activity" (George L. Ellman, K. Diane Courtney, Valentino Andres et al., 1961), with 27,264 citations. Next come "A new generation of Ca2+ indicators with greatly improved fluorescence properties." (21,798) and "New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening" (9,830).

Most cited papers
#PaperReleasedCitations
1 A new and rapid colorimetric determination of acetylcholinesterase activity George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology Jul 1961 27,264
2 A new generation of Ca2+ indicators with greatly improved fluorescence properties. Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry Open access Mar 1985 21,798
3 New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute 4 Jul 1990 9,830
4 THE GREEN FLUORESCENT PROTEIN Roger Y. Tsien · Annual Review of Biochemistry Review Jun 1998 6,213
5 Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Manfred Gossen, Heidelberg Bujard · Proceedings of the National Academy of Sciences Open access 15 Jun 1992 5,005
All 99 most cited papers, with filters and sorting

Where is bioluminescence and chemiluminescence research research done?

The largest centres of bioluminescence and chemiluminescence research research in 2022-now are Moscow (Russia), Beijing (China), Tokyo (Japan) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Madison and Moscow.

Largest cities, 2022-now

  1. 1 MoscowRussia 87 works
  2. 2 BeijingChina 86 works
  3. 3 TokyoJapan 53 works
  4. 4 ShanghaiChina 42 works
  5. 5 NanjingChina 35 works
  6. 6 GuangzhouChina 30 works
  7. 7 HangzhouChina 29 works
  8. 8 ParisFrance 26 works
  9. 9 New YorkUnited States 22 works
  10. 10 MadisonUnited States 21 works

Where it is the local speciality

  1. MadisonUS · 20.5 works6.8×
  2. MoscowRU · 87.3 works3.4×
← less than its size predicts1×more →

Location quotient: how much more of its research is in bioluminescence and chemiluminescence research than the world average.

See bioluminescence and chemiluminescence research on the map

Where is the best place to study bioluminescence and chemiluminescence research?

Among universities, judged by research, Lomonosov Moscow State University, Harvard University and Stanford University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 10.75%fractional works in this field (log) →share of work in the world top 10% →Stanford UniversityHarvard UniversityLomonosov Moscow Sta…The University of To…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Lomonosov Moscow State UniversityRussia 67.14.7%9.2×17 +55.1%
2Harvard UniversityUnited States 57.222.4%1.4×10 -38.3%
3Stanford UniversityUnited States 54.822.5%2.8×9 -34.4%
4The University of TokyoJapan 45.84.7%4.1×12 +30.6%
5Zhejiang UniversityChina 37.215.0%1.4×8 +65.4%
6Universidade de São PauloBrazil 34.54.0%2.5×11 -5.5%
7Shanghai Jiao Tong UniversityChina 31.812.7%1.2×8 +68.2%
8Tamil Nadu Veterinary and Animal Sciences UniversityIndia 19.60.0%101.6×9 -

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in bioluminescence and chemiluminescence research, country by country

Is bioluminescence and chemiluminescence research research growing?

Output in 2022-2025 was 7% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are bioluminescence and chemiluminescence research.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is bioluminescence and chemiluminescence research as a percentage of every work published that year, 0.011% in 2024.

still counting0.025%0.050%0.075%bioluminescence and chemiluminescence research0.011% in 202519801990200020102020

Fractional works of bioluminescence and chemiluminescence research over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%bioluminescence and chemiluminescence research10.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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