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Topic · Organic Chemistry

Quinazolinone synthesis and applications

Quinazolinone synthesis and applications is a research topic within Organic Chemistry. Science Explorer counts 15k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the chemistry, synthesis, and pharmacological properties of quinazoline compounds, including indirubin derivatives. It covers a wide range of topics such as inhibition of protein kinases, antitumor activity, antimicrobial effects, and anti-inflammatory properties.

  • Quinazoline
  • Indirubin
  • Synthesis
  • Anticancer
  • Alkaloids
  • Inhibition
  • Catalyzed
  • Antimicrobial
  • Anti-inflammatory
  • Biological Evaluation
Research works
15k
fractional, since 1950
In the world top 10%
1.5k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+6%
the tick is no change
Largest producer
China
35% of the 10 largest, 2022-now
Quinazolinone synthesis and applications

Which countries lead Quinazolinone synthesis and applications research?

By volume, China and India publish the most (589 and 436 works in 2022-now).

By volume, 2022-now

  1. 1 China 589 works
  2. 2 India 436 works
  3. 3 United States 159 works
  4. 4 Egypt 122 works
  5. 5 Russia 89 works
  6. 6 Iran 86 works
  7. 7 Saudi Arabia 66 works
  8. 8 Japan 50 works
  9. 9 Türkiye 46 works
  10. 10 South Korea 43 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 35.0%India: 25.8%United States: 9.4%Egypt: 7.2%6 others listed: 22.6%35%largest
China589 · 35.0%India436 · 25.8%United States159 · 9.4%Egypt122 · 7.2%6 others listed381 · 22.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Quinazolinone synthesis and applications research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Quinazolinone synthesis and applications research, followed by National Research Centre and Council of Scientific and Industrial Research.

By volume, 2022-now

  1. 1 Russian Academy of SciencesRussia 33 works
  2. 2 National Research CentreEgypt 17 works
  3. 3 Council of Scientific and Industrial ResearchIndia 16 works
  4. 4 Cairo UniversityEgypt 15 works
  5. 5 King Saud UniversitySaudi Arabia 15 works
  6. 6 Guizhou UniversityChina 15 works
  7. 7 Chinese Academy of SciencesChina 15 works
  8. 8 Centre National de la Recherche ScientifiqueFrance 14 works
  9. 9 Shenyang Pharmaceutical UniversityChina 11 works
  10. 10 Al-Azhar UniversityEgypt 11 works

Who are the leading researchers in Quinazolinone synthesis and applications?

The most-cited researchers publishing on Quinazolinone synthesis and applications include Matthew M. Meyerson, Hagop M. Kantarjian and Wei Huang.

  1. 1 Matthew M. Meyerson United States 280k citations
  2. 2 Hagop M. Kantarjian United States 273k citations
  3. 3 Wei Huang China 267k citations
  4. 4 Kai You Wang China 224k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Quinazolinone synthesis and applications?

The most cited paper in Quinazolinone synthesis and applications is "Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase" (Margaret F. Favata, Kurumi Y. Horiuchi, Elizabeth J. Manos et al., 1998), with 3,045 citations. Next come "Epidermal growth factor-related peptides and their receptors in human malignancies" (2,699) and "TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function" (2,631).

Most cited papers
#PaperReleasedCitations
1 Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase Margaret F. Favata, Kurumi Y. Horiuchi, Elizabeth J. Manos et al. · Journal of Biological Chemistry Open access Jul 1998 3,045
2 Epidermal growth factor-related peptides and their receptors in human malignancies David S. Salomon, Ralf Brandt, Fortunato Ciardiello et al. · Critical Reviews in Oncology/Hematology Jul 1995 2,699
3 TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function Anjana Rao, Chun Huai Luo, Patrick G. Hogan · Annual Review of Immunology Review Apr 1997 2,631
4 Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor Jeffrey H. Hanke, Joseph P. Gardner, Robert L. Dow et al. · Journal of Biological Chemistry Open access 1996 1,962
5 A small molecule–kinase interaction map for clinical kinase inhibitors Miles A. Fabian et al. · Nature Biotechnology Open access 13 Feb 2005 1,927
All 99 most cited papers, with filters and sorting

Where is Quinazolinone synthesis and applications research done?

The largest centres of Quinazolinone synthesis and applications research in 2022-now are Beijing (China), Cairo (Egypt), Giza (Egypt) and Hyderabad (India). Among places with at least 20 works in it, it is an unusually large share of all research in Giza, Guiyang and Hyderabad.

Largest cities, 2022-now

  1. 1 BeijingChina 55 works
  2. 2 CairoEgypt 39 works
  3. 3 GizaEgypt 34 works
  4. 4 HyderabadIndia 34 works
  5. 5 ShanghaiChina 33 works
  6. 6 GuangzhouChina 27 works
  7. 7 RiyadhSaudi Arabia 26 works
  8. 8 GuiyangChina 26 works
  9. 9 MoscowRussia 24 works
  10. 10 TehranIran 23 works

Where it is the local speciality

  1. GizaEG · 34.0 works11×
  2. GuiyangCN · 25.6 works8.8×
  3. HyderabadIN · 33.9 works8.2×
  4. CairoEG · 38.5 works7.5×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Quinazolinone synthesis and applications than the world average.

See Quinazolinone synthesis and applications on the map

Where is the best place to study Quinazolinone synthesis and applications?

Among universities, judged by research, Cairo University, King Saud University and Guizhou University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 15.33%fractional works in this field (log) →share of work in the world top 10% →Cairo UniversityAl-Azhar UniversityKing Saud UniversityGuizhou University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Cairo UniversityEgypt 88.332.9%10.6×16 +17.9%
2King Saud UniversitySaudi Arabia 80.418.2%7.9×15 +30.2%
3Guizhou UniversityChina 74.918.2%14.8×15 +50.3%
4Al-Azhar UniversityEgypt 72.228.0%15.2×11 -11.8%
5Mansoura UniversityEgypt 38.710.1%9.7×8 +13.4%
6Academy of Scientific and Innovative ResearchIndia 36.78.3%15.6×9 +4.4%
7Zhengzhou UniversityChina 30.513.2%4.1×9 -22.9%
8Sichuan UniversityChina 29.321.3%1.9×8 -6.7%
9Shenyang Pharmaceutical UniversityChina 27.81.2%45.5×11 -12.4%
10University of GuilanIran 23.31.9%33.3×8 +75.9%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Quinazolinone synthesis and applications, country by country

Is Quinazolinone synthesis and applications research growing?

Output in 2022-2025 was 6% higher than in 2018-2021, peaking in 2013. The fastest-growing topics are Quinazolinone synthesis and applications.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Quinazolinone synthesis and applications as a percentage of every work published that year, 0.0089% in 2024.

still counting0.010%0.020%0.030%Quinazolinone synthesis and applications0.0084% in 202519801990200020102020

Fractional works of Quinazolinone synthesis and applications over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Quinazolinone synthesis and applications10.1% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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