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Topic · Physiology

Tuberous Sclerosis Complex Research

Tuberous Sclerosis Complex Research is a research topic within Physiology. Science Explorer counts 12k research works in it since 1950. 10.5% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on Tuberous Sclerosis Complex (TSC) and related disorders, including Lymphangioleiomyomatosis and Angiomyolipoma. It covers various aspects such as genetic mutations, neurological manifestations, use of mTOR inhibitors, diagnostic criteria, and the role of hamartin and tuberin proteins. Additionally, it explores the association with epilepsy and cognitive impairment.

  • Tuberous Sclerosis Complex
  • Lymphangioleiomyomatosis
  • Angiomyolipoma
  • mTOR Inhibitors
  • Neurological Manifestations
  • Genetic Mutations
  • Epilepsy
  • Diagnostic Criteria
  • Hamartin and Tuberin Proteins
  • Cognitive Impairment
Research works
12k
fractional, since 1950
In the world top 10%
1.3k
per year above
Top-10% rate
10.5%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+11%
the tick is no change

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Tuberous Sclerosis Complex Research research?

By volume, the United States and China publish the most (531 and 370 works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 531 works
  2. 2 China 370 works
  3. 3 India 152 works
  4. 4 Japan 123 works
  5. 5 Italy 83 works
  6. 6 Germany 70 works
  7. 7 United Kingdom 63 works
  8. 8 France 54 works
  9. 9 Türkiye 52 works
  10. 10 Canada 49 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 34.3%China: 23.9%India: 9.8%Japan: 8.0%6 others listed: 24.0%34%largest
United States531 · 34.3%China370 · 23.9%India152 · 9.8%Japan123 · 8.0%6 others listed371 · 24.0%

Shares of the rows listed above, not of the whole node.

Which institutions lead Tuberous Sclerosis Complex Research research?

By volume in 2022–2025, Chinese Academy of Medical Sciences & Peking Union Medical College publishes the most Tuberous Sclerosis Complex Research research, followed by Harvard University and All India Institute of Medical Sciences.

Who are the leading researchers in Tuberous Sclerosis Complex Research?

The most-cited researchers publishing on Tuberous Sclerosis Complex Research include Thomas Schwarz and James Larkin.

  1. 1 Thomas Schwarz United States 3.1k citations
  2. 2 James Larkin United Kingdom 2.3k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Tuberous Sclerosis Complex Research research done?

The largest centres of Tuberous Sclerosis Complex Research research in 2022–2025 are Beijing (China), Tokyo (Japan), Boston (United States) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Cincinnati.

Largest cities, 2022–2025

  1. 1 Beijing China 61 works
  2. 2 Tokyo Japan 32 works
  3. 3 Boston United States 28 works
  4. 4 Shanghai China 27 works
  5. 5 Guangzhou China 27 works
  6. 6 New York United States 26 works
  7. 7 London United Kingdom 25 works
  8. 8 Cincinnati United States 23 works
  9. 9 Chengdu China 23 works
  10. 10 Paris France 22 works

Where it is the local speciality

  1. CincinnatiUS · 23.2 works14×
← less than its size predictsmore →

Location quotient: how much more of its research is in Tuberous Sclerosis Complex Research than the world average.

See Tuberous Sclerosis Complex Research on the map

Where is the best place to study Tuberous Sclerosis Complex Research?

Among universities, judged by research, Harvard University, University of Cincinnati and Chinese Academy of Medical Sciences & Peking Union Medical College score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 7.46667%fractional works in this node (log) →share in the world top 10% →Harvard University: 12, 23.6%University of Cincinnati: 10, 4.8%Chinese Academy of Medical Sciences & Peking Union Medical College: 14, 5.0%Post Graduate Institute of Medical Education and Research: 9, 0.3%All India Institute of Medical Sciences: 11, 0.4%Sichuan University: 8, 10.7%Harvard UniversityChinese Academy of M…University of Cincin…Post Graduate Instit…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Harvard UniversityUnited States 63.723.6%4.6×12 -13.4%
2 University of CincinnatiUnited States 50.74.8%16.5×10 +64.1%
3 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 45.25.0%6.8×14 +7.9%
4 Post Graduate Institute of Medical Education and ResearchIndia 44.90.3%13.5×9 +165.3%
5 All India Institute of Medical SciencesIndia 37.30.4%8.8×11 +26.1%
6 Sichuan UniversityChina 19.110.7%2.3×8 +31.0%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Tuberous Sclerosis Complex Research research growing?

Output in 2018–2022 was 11% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Tuberous Sclerosis Complex Research.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.