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Company · Cambridge · United Kingdom

Horizon Discovery (United Kingdom)

horizondiscovery.comROR OpenAlex
Research works
87
▼ 53% vs 2018-21
Citations
1.2k
13.6 per fractional work
Top-10% rate
9.1%
all institutions 10.0%
Open access
39%
world 40%
International
25%
world 18%
Horizon Discovery (United Kingdom)

Not ranked overall: Horizon Discovery (United Kingdom) is under the volume floor below which a citation excellence rate is noise. Not ranked is not the same as ranked last.

Which fields of science does Horizon Discovery (United Kingdom) work in?

In all years, 61% of research at Horizon Discovery (United Kingdom) is in Life Sciences, 23% in Health Sciences. Its largest fields are Biochemistry, Genetics and Molecular Biology (56%), Medicine (21%), Engineering (5%). It does 3.5× the world's share of Life Sciences.

Life Sciences: 53 fractional works · 61.1% of its workBiochemistry, Genetics and Molecular Biology: 49 fractional works · 55.9% of its workMolecular Biology: 35 fractional works · 40.0% of its workCancer Research: 8 fractional works · 8.8% of its workGenetics: 3 fractional works · 3.2% of its workBiophysics: 1 fractional works · 1.2% of its workCell Biology: 1 fractional works · 1.0% of its workBiotechnology: 0 fractional works · 0.6% of its workAging: 0 fractional works · 0.5% of its workBiochemistry: 0 fractional works · 0.5% of its workImmunology and Microbiology: 3 fractional works · 3.4% of its workImmunology: 3 fractional works · 3.2% of its workSmaller subfields together: 0 fractional works · 0.2% of its workNeuroscience: 1 fractional works · 1.2% of its workEndocrine and Autonomic Systems: 0 fractional works · 0.4% of its workCognitive Neuroscience: 0 fractional works · 0.4% of its workCellular and Molecular Neuroscience: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.1% of its workAgricultural and Biological Sciences: 1 fractional works · 0.6% of its workPlant Science: 1 fractional works · 0.6% of its workHealth Sciences: 20 fractional works · 22.6% of its workMedicine: 18 fractional works · 21.2% of its workOncology: 10 fractional works · 11.3% of its workPulmonary and Respiratory Medicine: 2 fractional works · 2.6% of its workPathology and Forensic Medicine: 1 fractional works · 1.5% of its workRadiology, Nuclear Medicine and Imaging: 1 fractional works · 1.3% of its workPsychiatry and Mental health: 0 fractional works · 0.6% of its workPhysiology: 0 fractional works · 0.5% of its workCardiology and Cardiovascular Medicine: 0 fractional works · 0.4% of its workHematology: 0 fractional works · 0.4% of its workImmunology and Allergy: 0 fractional works · 0.4% of its workEpidemiology: 0 fractional works · 0.4% of its workSurgery: 0 fractional works · 0.3% of its workGenetics: 0 fractional works · 0.3% of its workInfectious Diseases: 0 fractional works · 0.2% of its workSmaller subfields together: 1 fractional works · 0.9% of its workHealth Professions: 1 fractional works · 0.9% of its workSpeech and Hearing: 1 fractional works · 0.8% of its workSmaller subfields together: 0 fractional works · 0.1% of its workVeterinary: 0 fractional works · 0.5% of its workSmall Animals: 0 fractional works · 0.5% of its workPhysical Sciences: 11 fractional works · 12.9% of its workEngineering: 4 fractional works · 5.1% of its workBiomedical Engineering: 2 fractional works · 2.0% of its workCivil and Structural Engineering: 1 fractional works · 1.2% of its workOcean Engineering: 1 fractional works · 0.8% of its workElectrical and Electronic Engineering: 0 fractional works · 0.4% of its workIndustrial and Manufacturing Engineering: 0 fractional works · 0.4% of its workBuilding and Construction: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.1% of its workComputer Science: 3 fractional works · 3.8% of its workHuman-Computer Interaction: 1 fractional works · 1.1% of its workArtificial Intelligence: 1 fractional works · 1.0% of its workComputational Theory and Mathematics: 1 fractional works · 0.9% of its workComputer Networks and Communications: 0 fractional works · 0.4% of its workComputer Vision and Pattern Recognition: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.2% of its workEarth and Planetary Sciences: 2 fractional works · 2.1% of its workGeophysics: 2 fractional works · 1.7% of its workOceanography: 0 fractional works · 0.4% of its workChemistry: 1 fractional works · 0.7% of its workOrganic Chemistry: 1 fractional works · 0.6% of its workSmaller subfields together: 0 fractional works · 0.1% of its workEnvironmental Science: 1 fractional works · 0.6% of its workMaterials Science: 0 fractional works · 0.4% of its workMaterials Chemistry: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.2% of its workEnergy: 0 fractional works · 0.1% of its workSocial Sciences: 3 fractional works · 3.4% of its workPsychology: 1 fractional works · 1.7% of its workClinical Psychology: 1 fractional works · 1.0% of its workApplied Psychology: 1 fractional works · 0.6% of its workSmaller subfields together: 0 fractional works · 0.0% of its workSocial Sciences: 1 fractional works · 1.6% of its workEducation: 0 fractional works · 0.6% of its workSafety Research: 0 fractional works · 0.5% of its workSociology and Political Science: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.2% of its workBusiness, Management and Accounting: 0 fractional works · 0.1% of its workEconomics, Econometrics and Finance: 0 fractional works · 0.1% of its workALL ITS WORKHorizon Discovery(United Kingdom)87fractional works, all years
Life Sciences61%Physical Sciences13%Health Sciences23%Social Sciences3%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in all years. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 18 fields, with their numbers
    1. Biochemistry, Genetics and Molecular Biology4955.9%
    2. Immunology and Microbiology33.4%
    3. Neuroscience11.2%
    4. Agricultural and Biological Sciences10.6%
    1. Medicine1821.2%
    2. Health Professions10.9%
    3. Veterinary00.5%
    1. Engineering45.1%
    2. Computer Science33.8%
    3. Earth and Planetary Sciences22.1%
    4. Chemistry10.7%
    5. Environmental Science10.6%
    6. Materials Science00.4%
    7. Energy00.1%
    1. Psychology11.7%
    2. Social Sciences11.6%
    3. Business, Management and Accounting00.1%
    4. Economics, Econometrics and Finance00.1%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.26× its world share, 0 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 7.46× its world share, 4 worksBiochemistry, Geneti…Immunology and Microbiology: 4.14× its world share, 0 worksImmunology and Micro…Neuroscience: 2.27× its world share, 0 worksNeuroscienceChemistry: 2.34× its world share, 0 worksChemistryComputer Science: 1.09× its world share, 1 worksComputer ScienceEngineering: 0.20× its world share, 0 worksEngineeringEnvironmental Science: 0.15× its world share, 0 worksEnvironmental ScienceMaterials Science: 0.35× its world share, 0 worksMaterials ScienceMedicine: 1.65× its world share, 3 worksMedicinePsychology: 0.20× its world share, 0 worksPsychologySocial Sciences: 0.14× its world share, 0 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Biochemistry, Genetics and Molecular Biology, 7.5×. Every wedge is a field page.

All 12 fields, with their numbers
  1. Biochemistry, Genetics and Molecular Biology7.46×4 works
  2. Immunology and Microbiology4.14×0 works
  3. Chemistry2.34×0 works
  4. Neuroscience2.27×0 works
  5. Medicine1.65×3 works
  6. Computer Science1.09×1 works
  7. Materials Science0.35×0 works
  8. Agricultural and Biological Sciences0.26×0 works
  9. Engineering0.20×0 works
  10. Psychology0.20×0 works
  11. Environmental Science0.15×0 works
  12. Social Sciences0.14×0 works

Who are the top researchers at Horizon Discovery (United Kingdom)?

Ranked on the quality score, Steffen Lawo, Holly M. Astley and David A. Sorrell lead among researchers whose main affiliation is Horizon Discovery (United Kingdom).

  1. 1 Steffen Lawo United Kingdom · #403,266 worldwide 2.3k citations · 27 works
  2. 2 Holly M. Astley United Kingdom · #852,291 worldwide 590 citations · 45 works
  3. 3 David A. Sorrell United Kingdom · #1,227,951 worldwide 1.4k citations · 46 works
  4. 4 Benedict C. S. Cross United Kingdom · #1,296,620 worldwide 1.5k citations · 37 works
  5. 5 Julie A. Wickenden United Kingdom · #1,304,882 worldwide 716 citations · 15 works
  6. 6 Annette S. Little United Kingdom · #1,476,399 worldwide 731 citations · 18 works
  7. 7 Chris J Torrance United Kingdom · #1,591,895 worldwide 1.3k citations · 67 works
  8. 8 Ceri M. Wiggins United Kingdom · #1,963,801 worldwide 602 citations · 24 works
  9. 9 Tim M. E. Scales United Kingdom · #3,971,073 worldwide 295 citations · 17 works
  10. 10 Nicola Jane McCarthy United Kingdom · #7,577,696 worldwide 2.4k citations · 479 works
All ranked researchers at Horizon Discovery (United Kingdom)

What are the most cited papers from Horizon Discovery (United Kingdom)?

The most cited paper from Horizon Discovery (United Kingdom) is "Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib)" (Ursula A. Germann et al., 2017), with 239 citations. Next come "A generic strategy for CRISPR-Cas9-mediated gene tagging" (212) and "A Quantitative Comparison of Antibodies to Programmed Cell Death 1 Ligand 1" (202).

Most cited papers
#PaperReleasedCitations
1 Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib) Ursula A. Germann et al. · Molecular Cancer Therapeutics 22 Sep 2017 239
2 A generic strategy for CRISPR-Cas9-mediated gene tagging Daniel H. Lackner, Alexia Carré, Paloma M. Guzzardo et al. · Nature Communications Open access 17 Dec 2015 212
3 A Quantitative Comparison of Antibodies to Programmed Cell Death 1 Ligand 1 Patricia Gaule, James William Smithy, Maria I Toki et al. · JAMA Oncology Open access 19 Aug 2016 202
4 Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA Davina Gillian Gale et al. · PLoS ONE Open access 16 Mar 2018 174
5 Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT) Alexandra R. Grassian, Fallon Lin, Rosemary Barrett et al. · Journal of Biological Chemistry Open access 4 Oct 2012 142
All 60 most cited papers, with filters and sorting

Which keywords describe research at Horizon Discovery (United Kingdom)?

By fractional works in all years, weighted toward what it does more of than the world: Genome Engineering, RNA-Guided, Cancer, Immunotherapy, Targeted Therapy, Cancer Therapy, Gene Therapy and Gene Expression.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in all years in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Genome Engineering9▲ 183×1 topic
  2. RNA-Guided9▲ 183×1 topic
  3. Cancer8▲ 6.8×18 topics
  4. Immunotherapy6▲ 10×8 topics
  5. Targeted Therapy5▲ 29×3 topics
  6. Cancer Therapy5▲ 9.4×10 topics
  7. Gene Therapy5▲ 22×4 topics
  8. Gene Expression5▲ 9.4×12 topics
  9. Genomic Instability5▲ 41×2 topics
  10. Cancer Genomics4▲ 93×1 topic
  11. Mutational Signatures4▲ 93×1 topic
  12. Tumor Regression4▲ 55×2 topics
  13. Metabolism4▲ 7.2×4 topics
  14. CAR T Cells4▲ 97×1 topic
  15. Cancer Immunotherapy4▲ 31×2 topics
  16. Chimeric Antigen Receptor4▲ 97×1 topic
  17. Tumor Microenvironment4▲ 12×6 topics
  18. Nanoparticles3▲ 2.8×2 topics
  19. Biosensors3▲ 6.2×2 topics
  20. Chemotherapy3▲ 4.9×5 topics
  21. DNA nanotechnology3▲ 32×1 topic
  22. Self-Assembly3▲ 8.4×1 topic
  23. Cell Growth3▲ 97×2 topics
  24. Signaling3▲ 28×1 topic
  25. mTOR3▲ 149×1 topic
  26. Genomic Integration3▲ 29×2 topics
  27. HIF-12▲ 37×1 topic
  28. Warburg Effect2▲ 37×1 topic
  29. AAV2▲ 40×1 topic
  30. Precision Medicine2▲ 8.1×4 topics
  31. Transcriptional Regulation2▲ 10×6 topics
  32. Viral Vectors2▲ 40×1 topic
  33. Cancer Progression2▲ 10×5 topics
  34. RNA Interference2▲ 21×1 topic
  35. siRNA Delivery2▲ 32×1 topic
  36. RNA-Seq2▲ 25×2 topics
  37. Tumor Suppression2▲ 20×3 topics
  38. Glycosylation2▲ 10×3 topics
  39. Single-Cell2▲ 105×1 topic
  40. Transcriptomics2▲ 105×1 topic

Which research topics does Horizon Discovery (United Kingdom) publish most on?

By volume in 2022-now: CAR-T cell therapy research, Computational Drug Discovery Methods, Colorectal Cancer Treatments and Studies and Melanoma and MAPK Pathways.

CAR-T cell therapy research: 1 fractional worksComputational Drug Discovery Methods: 1 fractional worksColorectal Cancer Treatm…0Colorectal Cancer Treatments and Studies: 0 fractional worksMelanoma and MAPK Pathways0Melanoma and MAPK Pathways: 0 fractional worksCancer Mechanisms and Therapy: 0 fractional worksPluripotent Stem Cells Research: 0 fractional worksCRISPR and Genetic Engin…0CRISPR and Genetic Engineering: 0 fractional worksAdvanced Breast Cancer Therapies: 0 fractional worksCell Adhesion Molecules Research: 0 fractional worksViral Infectious Disease…0Viral Infectious Diseases and Gene Expression in Insects: 0 fractional works
OncologyComputational Theory and MathematicsMolecular BiologyPathology and Forensic Medicine2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 CAR-T cell therapy research Oncology 1 works
  2. 2 Computational Drug Discovery Methods Computational Theory and Mathematics 1 works
  3. 3 Colorectal Cancer Treatments and Studies Oncology 0 works
  4. 4 Melanoma and MAPK Pathways Molecular Biology 0 works
  5. 5 Cancer Mechanisms and Therapy Pathology and Forensic Medicine 0 works
  6. 6 Pluripotent Stem Cells Research Molecular Biology 0 works
  7. 7 CRISPR and Genetic Engineering Molecular Biology 0 works
  8. 8 Advanced Breast Cancer Therapies Pulmonary and Respiratory Medicine 0 works
  9. 9 Cell Adhesion Molecules Research Immunology and Allergy 0 works
  10. 10 Viral Infectious Diseases and Gene Expression in Insects Molecular Biology 0 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available39.0%not open61.0%

World: 40% of research is openly available.

with international co-authors25.0%domestic only75.0%

World: 18% is written across borders.

How has Horizon Discovery (United Kingdom)'s research output changed?

Output in 2022-2025 was 53% lower than in 2018-2021.

still counting1990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Horizon Discovery (United Kingdom) as a percentage of every work published that year, 0.000028% in 2024.

still counting0.00020%0.00040%Horizon Discovery (United Kingdom)0.000019% in 20251990200020102020

Fractional works of Horizon Discovery (United Kingdom) over all fractional works that year. How the balance of science has shifted.

Other research institutions in Cambridge

All research institutions in Cambridge

Research measures only: rankings here say nothing about teaching, admissions or student experience. Comparable institutions and collaboration partners have tabs of their own, above.

Discussion

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