Cancer therapeutics and mechanisms
Cancer therapeutics and mechanisms is a research topic within Molecular Biology. Science Explorer counts 35k research works in it since 1950. 14.8% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the structure, function, inhibition, and genetic variants of DNA topoisomerases, particularly their roles in chemotherapy, the mechanism of action of specific inhibitors such as irinotecan and quinolones, and their impact on genomic stability. The papers also explore the potential use of genetic variants in predicting drug toxicity and treatment outcomes.
- Topoisomerases
- DNA
- Inhibitors
- Chemotherapy
- Genetic Variants
- Irinotecan
- Quinolones
- Anticancer Drugs
- Enzyme Mechanism
- Genomic Stability
- Research works
- 35k fractional, since 1950
- In the world top 10%
- 5.2k per year above
- Top-10% rate
- 14.8% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +2% the tick is no change
Which countries lead Cancer therapeutics and mechanisms research?
By volume, China and the United States publish the most (798 and 680 works in 2022–2025).
By volume, 2022–2025
- 1 China 798 works
- 2 United States 680 works
- 3 India 489 works
- 4 Japan 130 works
- 5 Egypt 129 works
- 6 United Kingdom 97 works
- 7 Germany 95 works
- 8 Italy 95 works
- 9 Russia 94 works
- 10 Saudi Arabia 91 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Cancer therapeutics and mechanisms research?
By volume in 2022–2025, King Saud University publishes the most Cancer therapeutics and mechanisms research, followed by Chinese Academy of Medical Sciences & Peking Union Medical College and Shenyang Pharmaceutical University.
By volume, 2022–2025
- 1 King Saud UniversitySaudi Arabia 21 works
- 2 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 19 works
- 3 Shenyang Pharmaceutical UniversityChina 16 works
- 4 The University of Texas MD Anderson Cancer CenterUnited States 16 works
- 5 Cairo UniversityEgypt 15 works
- 6 Sun Yat-sen UniversityChina 14 works
- 7 Al-Azhar UniversityEgypt 13 works
- 8 Academy of Scientific and Innovative ResearchIndia 12 works
- 9 Sichuan UniversityChina 12 works
- 10 Vellore Institute of Technology UniversityIndia 12 works
Who are the leading researchers in Cancer therapeutics and mechanisms?
The most-cited researchers publishing on Cancer therapeutics and mechanisms include Hagop M. Kantarjian, Susan G. Arbuck and A. Rosowsky.
- 1 Hagop M. Kantarjian United States 4k citations
- 2 Susan G. Arbuck United States 3.5k citations
- 3 A. Rosowsky Switzerland 3.5k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Cancer therapeutics and mechanisms research done?
The largest centres of Cancer therapeutics and mechanisms research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Moscow (Russia). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda, Giza and Hyderabad.
Largest cities, 2022–2025
Where it is the local speciality
- BethesdaUS · 28.9 works6.5×
- GizaEG · 26.0 works4.8×
- HyderabadIN · 32.6 works4.8×
Location quotient: how much more of its research is in Cancer therapeutics and mechanisms than the world average.
Where is the best place to study Cancer therapeutics and mechanisms?
Among universities, judged by research, Al-Azhar University, King Saud University and Academy of Scientific and Innovative Research score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Al-Azhar UniversityEgypt | 78.9 | 41.4% | 9.2× | 13 | +158.8% |
| 2 | King Saud UniversitySaudi Arabia | 63.7 | 26.1% | 6.3× | 21 | +6.0% |
| 3 | Academy of Scientific and Innovative ResearchIndia | 61.5 | 20.0% | 10.4× | 12 | +460.0% |
| 4 | Cairo UniversityEgypt | 57.7 | 36.0% | 5.2× | 15 | +54.0% |
| 5 | Shenyang Pharmaceutical UniversityChina | 50.2 | 15.1% | 34.9× | 16 | -15.4% |
| 6 | China Pharmaceutical UniversityChina | 48.5 | 23.4% | 15.0× | 12 | -28.9% |
| 7 | Vellore Institute of Technology UniversityIndia | 41.0 | 17.7% | 3.2× | 12 | +246.1% |
| 8 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 40.9 | 14.2% | 5.4× | 19 | -19.3% |
| 9 | GITAM UniversityIndia | 37.3 | 2.8% | 10.2× | 8 | +139.0% |
| 10 | Mansoura UniversityEgypt | 33.1 | 18.3% | 5.6× | 9 | -16.5% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Cancer therapeutics and mechanisms research growing?
Output in 2018–2022 was 2% higher than in 2013–2017, peaking in 2022. The fastest-growing topics are Cancer therapeutics and mechanisms.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.