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Topic · Hematology

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation is a research topic within Hematology. Science Explorer counts 37k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the biology, regulation, and clinical applications of hematopoietic stem cells (HSCs) within the bone marrow niche. It covers topics such as HSC quiescence, stem cell aging, graft-versus-host disease, hematologic malignancies, and the role of mesenchymal stem cells in supporting HSC function. Additionally, it explores the mechanisms of stem cell mobilization and transplantation for therapeutic purposes.

  • Hematopoietic Stem Cells
  • Bone Marrow Niche
  • Graft-versus-Host Disease
  • Stem Cell Quiescence
  • Hematopoietic Cell Transplantation
  • Stem Cell Aging
  • Hematopoietic Progenitor Cells
  • Stem Cell Mobilization
  • Mesenchymal Stem Cells
  • Hematologic Malignancies
Research works
37k
fractional, since 1950
In the world top 10%
3.7k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+3%
the tick is no change
Largest producer
United States
39% of the 10 largest, 2022-now
Hematopoietic Stem Cell Transplantation

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Hematopoietic Stem Cell Transplantation research?

By volume, the United States and China publish the most (1.7k and 923 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.7k works
  2. 2 China 923 works
  3. 3 Japan 396 works
  4. 4 Germany 274 works
  5. 5 Italy 201 works
  6. 6 India 200 works
  7. 7 France 190 works
  8. 8 United Kingdom 165 works
  9. 9 Brazil 163 works
  10. 10 Spain 159 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 38.7%China: 21.2%Japan: 9.1%Germany: 6.3%6 others listed: 24.8%39%largest
United States1,684 · 38.7%China923 · 21.2%Japan396 · 9.1%Germany274 · 6.3%6 others listed1,079 · 24.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Hematopoietic Stem Cell Transplantation research?

By volume in 2022-now, Chinese Academy of Medical Sciences & Peking Union Medical College publishes the most Hematopoietic Stem Cell Transplantation research, followed by Harvard University and Peking University.

By volume, 2022-now

  1. 1 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 88 works
  2. 2 Harvard UniversityUnited States 86 works
  3. 3 Peking UniversityChina 86 works
  4. 4 National Institutes of HealthUnited States 61 works
  5. 5 The University of Texas MD Anderson Cancer CenterUnited States 59 works
  6. 6 Fred Hutch Cancer CenterUnited States 48 works
  7. 7 Soochow UniversityChina 44 works
  8. 8 Shanghai Jiao Tong UniversityChina 37 works
  9. 9 Mayo ClinicUnited States 34 works
  10. 10 InsermFrance 32 works

Who are the leading researchers in Hematopoietic Stem Cell Transplantation?

The most-cited researchers publishing on Hematopoietic Stem Cell Transplantation include Guido Kroemer, Gad A. Getz and Elaine R. Mardis.

  1. 1 Guido Kroemer France 386k citations
  2. 2 Gad A. Getz United States 364k citations
  3. 3 Elaine R. Mardis United States 346k citations
  4. 4 Shizuo Akira Japan 342k citations
  5. 5 Giuseppe Remuzzi Italy 328k citations
  6. 6 Matthias Egger Switzerland 326k citations
  7. 7 Gordon Henry Guyatt Canada 315k citations
  8. 8 Todd R. Golub United States 283k citations
  9. 9 Hagop M. Kantarjian United States 273k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Hematopoietic Stem Cell Transplantation?

The most cited paper in Hematopoietic Stem Cell Transplantation is "Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell" (Dominique A. Bonnet, John Edgar Dick, 1997), with 7,031 citations. Next come "National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group Report" (5,493) and "A cell initiating human acute myeloid leukaemia after transplantation into SCID mice" (4,789).

Most cited papers
#PaperReleasedCitations
1 Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Dominique A. Bonnet, John Edgar Dick · Nature Medicine Jul 1997 7,031
2 National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group Report Madan Jagasia et al. · Transplantation and Cellular Therapy Open access 19 Dec 2014 5,493
3 A cell initiating human acute myeloid leukaemia after transplantation into SCID mice Tsvee Lapidot, Christian Sirard, Josef H. Vormoor et al. · Nature Feb 1994 4,789
4 Human mesenchymal stem cells modulate allogeneic immune cell responses Sudeepta Aggarwal, Mark F. Pittenger · Blood Open access 20 Oct 2004 4,565
5 CLINICAL MANIFESTATIONS OF GRAFT-VERSUS-HOST DISEASE IN HUMAN RECIPIENTS OF MARROW FROM HL-A-MATCHED SIBLING DONOR,S Harold Glucksberg, Rainer Storb, A Fefer et al. · Transplantation Oct 1974 3,742
All 98 most cited papers, with filters and sorting

Where is Hematopoietic Stem Cell Transplantation research done?

The largest centres of Hematopoietic Stem Cell Transplantation research in 2022-now are Beijing (China), Paris (France), Tokyo (Japan) and Houston (United States). Among places with at least 20 works in it, it is an unusually large share of all research in Duarte, Lancaster and Memphis.

Largest cities, 2022-now

  1. 1 BeijingChina 218 works
  2. 2 ParisFrance 100 works
  3. 3 TokyoJapan 100 works
  4. 4 HoustonUnited States 84 works
  5. 5 New YorkUnited States 79 works
  6. 6 SeattleUnited States 78 works
  7. 7 BostonUnited States 74 works
  8. 8 TianjinChina 68 works
  9. 9 ShanghaiChina 66 works
  10. 10 GuangzhouChina 64 works

Where it is the local speciality

  1. DuarteUS · 22.1 works71×
  2. LancasterUS · 23.4 works53×
  3. MemphisUS · 24.9 works9.2×
  4. BethesdaUS · 59.6 works8.8×
  5. TampaUS · 33.9 works8.8×
  6. MilwaukeeUS · 28.6 works8.5×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Hematopoietic Stem Cell Transplantation than the world average.

See Hematopoietic Stem Cell Transplantation on the map

Where is the best place to study Hematopoietic Stem Cell Transplantation?

Among universities, judged by research, Harvard University, Peking University and Chinese Academy of Medical Sciences & Peking Union Medical College score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 16.32%fractional works in this field (log) →share of work in the world top 10% →Harvard UniversityUniversity of Washin…Peking UniversityChinese Academy of M…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 72.018.5%5.5×86 -13.6%
2Peking UniversityChina 68.012.1%8.5×86 +18.2%
3Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 62.68.7%17.0×88 +78.6%
4University of WashingtonUnited States 56.318.1%4.9×28 -10.0%
5Heidelberg UniversityGermany 55.321.0%5.6×21 -16.0%
6University of PennsylvaniaUnited States 54.915.5%4.3×22 +23.1%
7University of OxfordUnited Kingdom 52.628.7%1.4×10 -22.9%
8University of British ColumbiaCanada 51.412.4%2.5×15 +31.1%
9Shanghai Jiao Tong UniversityChina 50.611.6%2.6×37 +70.7%
10Karolinska InstitutetSweden 50.516.6%5.6×16 -10.2%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Hematopoietic Stem Cell Transplantation, country by country

Is Hematopoietic Stem Cell Transplantation research growing?

Output in 2022-2025 was 3% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Hematopoietic Stem Cell Transplantation.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Hematopoietic Stem Cell Transplantation as a percentage of every work published that year, 0.023% in 2024.

still counting0.025%0.050%0.075%Hematopoietic Stem Cell Transplantation0.024% in 202519801990200020102020

Fractional works of Hematopoietic Stem Cell Transplantation over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Hematopoietic Stem Cell Transplantation10.3% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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