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Topic · Hematology

Blood Coagulation and Thrombosis Mechanisms

Blood Coagulation and Thrombosis Mechanisms is a research topic within Hematology. Science Explorer counts 40k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on thrombosis, coagulation disorders, and their association with various conditions such as pregnancy, inflammation, and pediatric stroke. It covers topics related to thrombin signaling, protease-activated receptors, thrombophilia, antithrombotic therapy, and the role of coagulation factors in different pathological conditions.

  • Thrombin
  • Protease-Activated Receptors
  • Coagulation
  • Thrombophilia
  • Pregnancy
  • Inflammation
  • Pediatric Stroke
  • Factor V Leiden
  • Antithrombotic Therapy
  • Hemostasis
Research works
40k
fractional, since 1950
In the world top 10%
4k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-2%
the tick is no change
Largest producer
United States
36% of the 10 largest, 2022-now
Blood Coagulation and Thrombosis Mechanisms

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Blood Coagulation and Thrombosis Mechanisms research?

By volume, the United States and China publish the most (1.1k and 630 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.1k works
  2. 2 China 630 works
  3. 3 Japan 214 works
  4. 4 India 199 works
  5. 5 Germany 179 works
  6. 6 United Kingdom 171 works
  7. 7 Italy 170 works
  8. 8 France 167 works
  9. 9 Canada 147 works
  10. 10 Spain 127 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 35.9%China: 20.1%Japan: 6.8%India: 6.4%6 others listed: 30.7%36%largest
United States1,124 · 35.9%China630 · 20.1%Japan214 · 6.8%India199 · 6.4%6 others listed960 · 30.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Blood Coagulation and Thrombosis Mechanisms research?

By volume in 2022-now, University of North Carolina at Chapel Hill publishes the most Blood Coagulation and Thrombosis Mechanisms research, followed by Harvard University and Inserm.

By volume, 2022-now

  1. 1 University of North Carolina at Chapel HillUnited States 58 works
  2. 2 Harvard UniversityUnited States 42 works
  3. 3 InsermFrance 29 works
  4. 4 Sichuan UniversityChina 26 works
  5. 5 Shanghai Jiao Tong UniversityChina 26 works
  6. 6 Capital Medical UniversityChina 24 works
  7. 7 Johns Hopkins UniversityUnited States 23 works
  8. 8 University of TorontoCanada 21 works
  9. 9 Mayo ClinicUnited States 21 works
  10. 10 Peking UniversityChina 19 works

Who are the leading researchers in Blood Coagulation and Thrombosis Mechanisms?

The most-cited researchers publishing on Blood Coagulation and Thrombosis Mechanisms include George Davey Smith, Mark J. Daly and Stacey L. Gabriel.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Mark J. Daly United States 403k citations
  3. 3 Stacey L. Gabriel United States 402k citations
  4. 4 Peer Bork Germany 396k citations
  5. 5 Hermann Brenner Germany 343k citations
  6. 6 Emelia J. Benjamin United States 341k citations
  7. 7 Valery L. Feigin New Zealand 341k citations
  8. 8 Stephan Windecker Switzerland 338k citations
  9. 9 Giuseppe Remuzzi Italy 328k citations
  10. 10 Mika Kivimäki United Kingdom 318k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Blood Coagulation and Thrombosis Mechanisms?

The most cited paper in Blood Coagulation and Thrombosis Mechanisms is "Tissue Plasminogen Activator for Acute Ischemic Stroke" (The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study G, 1995), with 11,752 citations. Next come "Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury" (7,137) and "Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis" (6,170).

Most cited papers
#PaperReleasedCitations
1 Tissue Plasminogen Activator for Acute Ischemic Stroke The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study G · New England Journal of Medicine 14 Dec 1995 11,752
2 Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury Ravindra L. Mehta, John A. Kellum, Sudhir V. Shah et al. · Critical Care Open access Mar 2007 7,137
3 Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis Gordon R. Bernard, Jean‐Louis Vincent, Pierre‐François Laterre et al. · New England Journal of Medicine Open access 8 Mar 2001 6,170
4 Matrix Metalloproteinases: Regulators of the Tumor Microenvironment Kai Kessenbrock, Vicki Plaks, Zena Werb · Cell Open access Apr 2010 5,146
5 How Matrix Metalloproteinases Regulate Cell Behavior Mark D. Sternlicht, Zena Werb · Annual Review of Cell and Developmental Biology ReviewOpen access Nov 2001 3,957
All 100 most cited papers, with filters and sorting

Where is Blood Coagulation and Thrombosis Mechanisms research done?

The largest centres of Blood Coagulation and Thrombosis Mechanisms research in 2022-now are Beijing (China), Paris (France), Moscow (Russia) and Chapel Hill (United States). Among places with at least 20 works in it, it is an unusually large share of all research in Maastricht, Hamilton and Chapel Hill.

Largest cities, 2022-now

  1. 1 BeijingChina 91 works
  2. 2 ParisFrance 65 works
  3. 3 MoscowRussia 61 works
  4. 4 Chapel HillUnited States 57 works
  5. 5 LondonUnited Kingdom 57 works
  6. 6 ShanghaiChina 53 works
  7. 7 TokyoJapan 44 works
  8. 8 New YorkUnited States 44 works
  9. 9 BostonUnited States 43 works
  10. 10 PhiladelphiaUnited States 42 works

Where it is the local speciality

  1. MaastrichtNL · 20.8 works10×
  2. HamiltonCA · 25.9 works9.2×
  3. Chapel HillUS · 57.3 works6.8×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Blood Coagulation and Thrombosis Mechanisms than the world average.

See Blood Coagulation and Thrombosis Mechanisms on the map

Where is the best place to study Blood Coagulation and Thrombosis Mechanisms?

Among universities, judged by research, Harvard University, Maastricht University and University of Ottawa score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 18.3%fractional works in this field (log) →share of work in the world top 10% →Maastricht UniversityRadboud University N…Harvard UniversityUniversity of Ottawa
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 73.519.6%3.3×42 -19.7%
2Maastricht UniversityNetherlands 65.325.1%8.0×13 -31.0%
3University of OttawaCanada 63.516.8%5.7×16 +27.4%
4Radboud University NijmegenNetherlands 63.524.7%4.3×11 +102.4%
5McMaster UniversityCanada 62.021.0%7.8×18 -28.0%
6Johns Hopkins UniversityUnited States 61.814.8%3.7×23 +39.7%
7Royal College of Surgeons in IrelandIreland 57.912.2%20.6×9 +21.8%
8Medical University of ViennaAustria 56.813.9%11.5×15 +8.3%
9University of CopenhagenDenmark 56.617.3%2.7×10 +20.0%
10University of MichiganUnited States 54.017.6%3.0×19 -6.7%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Blood Coagulation and Thrombosis Mechanisms, country by country

Is Blood Coagulation and Thrombosis Mechanisms research growing?

Output in 2022-2025 was 2% lower than in 2018-2021, peaking in 2009.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Blood Coagulation and Thrombosis Mechanisms as a percentage of every work published that year, 0.017% in 2024.

still counting0.050%0.10%Blood Coagulation and Thrombosis Mechanisms0.019% in 202519801990200020102020

Fractional works of Blood Coagulation and Thrombosis Mechanisms over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Blood Coagulation and Thrombosis Mechanisms10.1% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

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