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Topic · Spectroscopy

Mass Spectrometry Techniques and Applications

Mass Spectrometry Techniques and Applications is a research topic within Spectroscopy. Science Explorer counts 86k research works in it since 1950. 9.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers covers advancements in mass spectrometry techniques, including ionization methods such as electrospray and MALDI, analysis of proteins and peptides, imaging mass spectrometry, and applications under ambient conditions. It also explores ion mobility and its role in proteomics and structural biology.

  • Mass Spectrometry
  • Ionization
  • Electrospray
  • Proteins
  • Imaging
  • Ambient Conditions
  • Ion Mobility
  • MALDI
  • Proteomics
  • Structural Biology
Research works
86k
fractional, since 1950
In the world top 10%
8.4k
per year above
Top-10% rate
9.8%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-10%
the tick is no change
Largest producer
United States
32% of the 10 largest, 2022-now
Mass Spectrometry Techniques and Applications

Which countries lead Mass Spectrometry Techniques and Applications research?

By volume, the United States and China publish the most (1.8k and 1.6k works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.8k works
  2. 2 China 1.6k works
  3. 3 Germany 542 works
  4. 4 Japan 377 works
  5. 5 France 290 works
  6. 6 United Kingdom 290 works
  7. 7 India 247 works
  8. 8 Russia 243 works
  9. 9 Canada 188 works
  10. 10 Spain 149 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 31.7%China: 28.2%Germany: 9.4%Japan: 6.5%6 others listed: 24.3%32%largest
United States1,835 · 31.7%China1,632 · 28.2%Germany542 · 9.4%Japan377 · 6.5%6 others listed1,407 · 24.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Mass Spectrometry Techniques and Applications research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most Mass Spectrometry Techniques and Applications research, followed by Centre National de la Recherche Scientifique and Russian Academy of Sciences.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 155 works
  2. 2 Centre National de la Recherche ScientifiqueFrance 129 works
  3. 3 Russian Academy of SciencesRussia 96 works
  4. 4 Max Planck SocietyGermany 48 works
  5. 5 Helmholtz Association of German Research CentresGermany 44 works
  6. 6 Purdue University West LafayetteUnited States 41 works
  7. 7 University of Chinese Academy of SciencesChina 39 works
  8. 8 University of Wisconsin–MadisonUnited States 36 works
  9. 9 Tsinghua UniversityChina 35 works
  10. 10 University of WashingtonUnited States 34 works

Who are the leading researchers in Mass Spectrometry Techniques and Applications?

The most-cited researchers publishing on Mass Spectrometry Techniques and Applications include Zhong Lin Wang, Rob Knight and John P. Perdew.

  1. 1 Zhong Lin Wang United States 491k citations
  2. 2 Rob Knight United States 468k citations
  3. 3 John P. Perdew United States 436k citations
  4. 4 George Davey Smith United Kingdom 435k citations
  5. 5 Peer Bork Germany 396k citations
  6. 6 Robert John Tibshirani United States 396k citations
  7. 7 Jun Wang China 340k citations
  8. 8 Matthias Mann Germany 308k citations
  9. 9 Róbert Langer United States 303k citations
  10. 10 Jeremy Grimshaw Canada 281k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Mass Spectrometry Techniques and Applications?

The most cited paper in Mass Spectrometry Techniques and Applications is "Detection of specific sequences among DNA fragments separated by gel electrophoresis" (E.M. Southern, 1975), with 32,849 citations. Next come "GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation" (16,214) and "MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification" (15,998).

Most cited papers
#PaperReleasedCitations
1 Detection of specific sequences among DNA fragments separated by gel electrophoresis E.M. Southern · Journal of Molecular Biology Nov 1975 32,849
2 GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation Berk Hess, Carsten Kutzner, David van der Spoel et al. · Journal of Chemical Theory and Computation Open access 2 Feb 2008 16,214
3 MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification Jürgen Cox, Matthias Mann · Nature Biotechnology 23 Nov 2008 15,998
4 CHARMM : A program for macromolecular energy, minimization, and dynamics calculations Bernard R. Brooks, Robert E. Bruccoleri, Barry D. Olafson et al. · Journal of Computational Chemistry Jun 1983 15,019
5 A low-viscosity epoxy resin embedding medium for electron microscopy Arthur R. Spurr · Journal of Ultrastructure Research 1969 12,956
All 100 most cited papers, with filters and sorting

Where is Mass Spectrometry Techniques and Applications research done?

The largest centres of Mass Spectrometry Techniques and Applications research in 2022-now are Beijing (China), Shanghai (China), Moscow (Russia) and Paris (France). Among places with at least 20 works in it, it is an unusually large share of all research in Gaithersburg.

Largest cities, 2022-now

  1. 1 BeijingChina 365 works
  2. 2 ShanghaiChina 139 works
  3. 3 MoscowRussia 114 works
  4. 4 ParisFrance 106 works
  5. 5 TokyoJapan 97 works
  6. 6 NanjingChina 69 works
  7. 7 WuhanChina 67 works
  8. 8 HangzhouChina 66 works
  9. 9 LondonUnited Kingdom 62 works
  10. 10 BerlinGermany 60 works

Where it is the local speciality

  1. GaithersburgUS · 24.1 works17×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Mass Spectrometry Techniques and Applications than the world average.

See Mass Spectrometry Techniques and Applications on the map

Where is the best place to study Mass Spectrometry Techniques and Applications?

Among universities, judged by research, Purdue University West Lafayette, University of California, Berkeley and University of Wisconsin–Madison score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 20.43%fractional works in this field (log) →share of work in the world top 10% →University of Califo…Purdue University We…Technical University…University of Wiscon…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Purdue University West LafayetteUnited States 69.123.2%6.6×41 -18.1%
2University of California, BerkeleyUnited States 66.526.3%2.9×18 +30.9%
3University of Wisconsin–MadisonUnited States 65.015.6%6.0×36 -1.6%
4Technical University of MunichGermany 64.022.3%3.6×21 +89.3%
5California Institute of TechnologyUnited States 62.114.9%8.6×20 +48.0%
6Maastricht UniversityNetherlands 60.731.4%4.1×10 -29.5%
7University of WashingtonUnited States 60.111.7%4.6×34 -16.0%
8Stanford UniversityUnited States 59.614.6%2.7×26 +2.7%
9University of Chinese Academy of SciencesChina 59.011.8%3.7×39 +8.3%
10Northeastern UniversityUnited States 58.832.5%4.9×10 -2.5%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Mass Spectrometry Techniques and Applications, country by country

Is Mass Spectrometry Techniques and Applications research growing?

Output in 2022-2025 was 10% lower than in 2018-2021, peaking in 2012.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Mass Spectrometry Techniques and Applications as a percentage of every work published that year, 0.032% in 2024.

still counting0.10%0.20%0.30%Mass Spectrometry Techniques and Applications0.028% in 202519801990200020102020

Fractional works of Mass Spectrometry Techniques and Applications over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Mass Spectrometry Techniques and Applications9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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