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Topic · Organic Chemistry

Multicomponent Synthesis of Heterocycles

Multicomponent Synthesis of Heterocycles is a research topic within Organic Chemistry. Science Explorer counts 24k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on recent advances in multicomponent reactions, particularly in the context of green chemistry, heterocyclic synthesis, catalysis, and organic synthesis. It explores the use of nanocatalysts, isocyanides, and asymmetric synthesis in the development of sustainable methodologies for drug discovery.

  • Multicomponent Reactions
  • Green Chemistry
  • Heterocyclic Synthesis
  • Catalysis
  • Organic Synthesis
  • Nanocatalysts
  • Isocyanides
  • Asymmetric Synthesis
  • Drug Discovery
  • Sustainable Methodologies
Research works
24k
fractional, since 1950
In the world top 10%
2.3k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-4%
the tick is no change
Largest producer
India
43% of the 10 largest, 2022-now
Multicomponent Synthesis of Heterocycles

Which countries lead Multicomponent Synthesis of Heterocycles research?

By volume, India and Iran publish the most (1.4k and 617 works in 2022-now).

By volume, 2022-now

  1. 1 India 1.4k works
  2. 2 Iran 617 works
  3. 3 China 460 works
  4. 4 Egypt 165 works
  5. 5 Saudi Arabia 133 works
  6. 6 Russia 122 works
  7. 7 United States 96 works
  8. 8 Iraq 96 works
  9. 9 Türkiye 70 works
  10. 10 Brazil 57 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

India: 43.3%Iran: 19.3%China: 14.4%Egypt: 5.2%6 others listed: 18.0%43%largest
India1,385 · 43.3%Iran617 · 19.3%China460 · 14.4%Egypt165 · 5.2%6 others listed575 · 18.0%

Shares of the rows listed above, not of the whole node.

Which institutions lead Multicomponent Synthesis of Heterocycles research?

By volume in 2022-now, Islamic Azad University, Tehran publishes the most Multicomponent Synthesis of Heterocycles research, followed by Russian Academy of Sciences and Bu-Ali Sina University.

By volume, 2022-now

  1. 1 Islamic Azad University, TehranIran 96 works
  2. 2 Russian Academy of SciencesRussia 54 works
  3. 3 Bu-Ali Sina UniversityIran 41 works
  4. 4 University of KashanIran 36 works
  5. 5 Council of Scientific and Industrial ResearchIndia 34 works
  6. 6 G.S. Science, Arts And Commerce CollegeIndia 33 works
  7. 7 Cairo UniversityEgypt 30 works
  8. 8 Centre National de la Recherche ScientifiqueFrance 27 works
  9. 9 Payame Noor UniversityIran 25 works
  10. 10 Savitribai Phule Pune UniversityIndia 24 works

Who are the leading researchers in Multicomponent Synthesis of Heterocycles?

The most-cited researchers publishing on Multicomponent Synthesis of Heterocycles include Richard A. Gibbs, Wei Huang and Ben Zhong Tang.

  1. 1 Richard A. Gibbs United States 292k citations
  2. 2 Wei Huang China 267k citations
  3. 3 Ben Zhong Tang China 261k citations
  4. 4 Kai You Wang China 224k citations
  5. 5 Seeram Ramakrishna Singapore 186k citations
  6. 6 Markus Antonietti Germany 185k citations
  7. 7 Qiang Zhang China 184k citations
  8. 8 Avelino Corma Spain 176k citations
  9. 9 J. B. Singh India 144k citations
  10. 10 Eduarda G. R. Fernandes Portugal 142k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Multicomponent Synthesis of Heterocycles?

The most cited paper in Multicomponent Synthesis of Heterocycles is "Multicomponent Reactions with Isocyanides" (Alexander S. S. Dömling, Ivar Ugi, 2000), with 4,073 citations. Next come "Controlled Microwave Heating in Modern Organic Synthesis" (3,606) and "The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures" (3,010).

Most cited papers
#PaperReleasedCitations
1 Multicomponent Reactions with Isocyanides Alexander S. S. Dömling, Ivar Ugi · Angewandte Chemie International Edition 15 Sep 2000 4,073
2 Controlled Microwave Heating in Modern Organic Synthesis Christian Oliver Kappe · Angewandte Chemie International Edition 23 Nov 2004 3,606
3 The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures Douglas A. Horton, Gregory T. Bourne, Mark L. Smythe · Chemical Reviews Review 22 Feb 2003 3,010
4 1,3‐Dipolar Cycloadditions. Past and Future Rolf Huisgen · Angewandte Chemie International Edition in English Oct 1963 2,898
5 Microwave assisted organic synthesis—a review Pelle Lidström, Jason P. Tierney, Bernard Wathey et al. · Tetrahedron Nov 2001 2,674
All 100 most cited papers, with filters and sorting

Where is Multicomponent Synthesis of Heterocycles research done?

The largest centres of Multicomponent Synthesis of Heterocycles research in 2022-now are Tehran (Iran), Hyderabad (India), Mumbai (India) and Giza (Egypt). Among places with at least 20 works in it, it is an unusually large share of all research in Yasuj, Kāshān and Īlām.

Largest cities, 2022-now

  1. 1 TehranIran 157 works
  2. 2 HyderabadIndia 63 works
  3. 3 MumbaiIndia 55 works
  4. 4 GizaEgypt 52 works
  5. 5 New DelhiIndia 52 works
  6. 6 CairoEgypt 51 works
  7. 7 HamadanIran 47 works
  8. 8 PuneIndia 46 works
  9. 9 MoscowRussia 42 works
  10. 10 BengaluruIndia 41 works

Where it is the local speciality

  1. YasujIR · 21.8 works98×
  2. KāshānIR · 35.6 works87×
  3. ĪlāmIR · 21.3 works73×
  4. BābolsarIR · 20.5 works70×
  5. HamadanIR · 47.3 works54×
  6. RajkotIN · 24.5 works48×
  7. KolhāpurIN · 25.6 works42×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Multicomponent Synthesis of Heterocycles than the world average.

See Multicomponent Synthesis of Heterocycles on the map

Where is the best place to study Multicomponent Synthesis of Heterocycles?

Among universities, judged by research, Ilam University, Bu-Ali Sina University and University of Mazandaran score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%60%mean 22.42%fractional works in this field (log) →share of work in the world top 10% →Ilam UniversityUniversity of Mazand…Bu-Ali Sina UniversityKing Khalid University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Ilam UniversityIran 64.551.7%114.8×19 -11.0%
2Bu-Ali Sina UniversityIran 53.517.9%134.5×41 +6.9%
3University of MazandaranIran 49.925.9%78.1×20 +52.7%
4King Khalid UniversitySaudi Arabia 49.313.8%9.9×12 +23.7%
5Al-Azhar UniversityEgypt 49.029.8%10.0×13 -9.3%
6Islamic Azad University, TehranIran 47.47.3%17.2×96 -52.0%
7Iran University of Science and TechnologyIran 47.316.7%23.6×22 -45.7%
8Sohag UniversityEgypt 47.124.6%19.3×8 +45.6%
9Jain UniversityIndia 44.622.3%11.6×10 +148.2%
10King Saud UniversitySaudi Arabia 44.414.2%6.0×20 +14.2%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Multicomponent Synthesis of Heterocycles, country by country

Is Multicomponent Synthesis of Heterocycles research growing?

Output in 2022-2025 was 4% lower than in 2018-2021, peaking in 2013.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Multicomponent Synthesis of Heterocycles as a percentage of every work published that year, 0.016% in 2024.

still counting0.020%0.040%Multicomponent Synthesis of Heterocycles0.016% in 202519801990200020102020

Fractional works of Multicomponent Synthesis of Heterocycles over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Multicomponent Synthesis of Heterocycles10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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