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Company · Nijmegen · Netherlands

Synthon (Netherlands)

synthon.comROR OpenAlex
Research works
76
▼ 31% vs 2018-21
Citations
2.1k
28.0 per fractional work
Top-10% rate
4.8%
all institutions 10.0%
Open access
44%
world 40%
International
31%
world 18%
Synthon (Netherlands)

Not ranked overall: Synthon (Netherlands) is under the volume floor below which an excellence rate is noise. Not ranked is not the same as ranked last.

Which fields of science does Synthon (Netherlands) work in?

In all years, 37% of research at Synthon (Netherlands) is in Physical Sciences, 31% in Health Sciences. Its largest fields are Medicine (31%), Chemistry (21%), Biochemistry, Genetics and Molecular Biology (19%). It does 1.7× the world's share of Life Sciences.

Physical Sciences: 28 fractional works · 37.2% of its workChemistry: 16 fractional works · 21.5% of its workOrganic Chemistry: 10 fractional works · 13.1% of its workSpectroscopy: 4 fractional works · 5.7% of its workPhysical and Theoretical Chemistry: 1 fractional works · 0.9% of its workInorganic Chemistry: 1 fractional works · 0.9% of its workAnalytical Chemistry: 1 fractional works · 0.7% of its workSmaller subfields together: 0 fractional works · 0.1% of its workEngineering: 6 fractional works · 7.3% of its workBiomedical Engineering: 2 fractional works · 3.0% of its workMechanics of Materials: 1 fractional works · 1.3% of its workControl and Systems Engineering: 1 fractional works · 1.2% of its workCivil and Structural Engineering: 0 fractional works · 0.7% of its workElectrical and Electronic Engineering: 0 fractional works · 0.5% of its workMechanical Engineering: 0 fractional works · 0.4% of its workOcean Engineering: 0 fractional works · 0.2% of its workMaterials Science: 3 fractional works · 4.1% of its workMaterials Chemistry: 2 fractional works · 2.0% of its workPolymers and Plastics: 1 fractional works · 1.3% of its workBiomaterials: 0 fractional works · 0.6% of its workElectronic, Optical and Magnetic Materials: 0 fractional works · 0.2% of its workChemical Engineering: 1 fractional works · 1.4% of its workCatalysis: 0 fractional works · 0.6% of its workFluid Flow and Transfer Processes: 0 fractional works · 0.4% of its workFiltration and Separation: 0 fractional works · 0.4% of its workEnvironmental Science: 1 fractional works · 1.3% of its workEcology: 0 fractional works · 0.5% of its workPollution: 0 fractional works · 0.3% of its workEnvironmental Engineering: 0 fractional works · 0.2% of its workIndustrial and Manufacturing Engineering: 0 fractional works · 0.2% of its workComputer Science: 1 fractional works · 0.7% of its workComputational Theory and Mathematics: 1 fractional works · 0.7% of its workEnergy: 0 fractional works · 0.4% of its workRenewable Energy, Sustainability and the Environment: 0 fractional works · 0.4% of its workEarth and Planetary Sciences: 0 fractional works · 0.2% of its workAtmospheric Science: 0 fractional works · 0.2% of its workPhysics and Astronomy: 0 fractional works · 0.2% of its workMathematics: 0 fractional works · 0.1% of its workHealth Sciences: 24 fractional works · 30.9% of its workMedicine: 23 fractional works · 30.7% of its workOncology: 7 fractional works · 9.5% of its workRadiology, Nuclear Medicine and Imaging: 7 fractional works · 8.8% of its workPharmacology: 2 fractional works · 2.2% of its workCardiology and Cardiovascular Medicine: 1 fractional works · 1.5% of its workReproductive Medicine: 1 fractional works · 1.3% of its workPulmonary and Respiratory Medicine: 1 fractional works · 0.9% of its workInfectious Diseases: 1 fractional works · 0.7% of its workNeurology: 0 fractional works · 0.5% of its workImmunology and Allergy: 0 fractional works · 0.5% of its workEpidemiology: 0 fractional works · 0.5% of its workFamily Practice: 0 fractional works · 0.4% of its workPediatrics, Perinatology and Child Health: 0 fractional works · 0.4% of its workPsychiatry and Mental health: 0 fractional works · 0.4% of its workPublic Health, Environmental and Occupational Health: 0 fractional works · 0.3% of its workPathology and Forensic Medicine: 0 fractional works · 0.3% of its workInternal Medicine: 0 fractional works · 0.2% of its workOphthalmology: 0 fractional works · 0.2% of its workEndocrinology, Diabetes and Metabolism: 0 fractional works · 0.2% of its workGenetics: 0 fractional works · 0.2% of its workSmaller subfields together: 1 fractional works · 1.7% of its workVeterinary: 0 fractional works · 0.1% of its workLife Sciences: 21 fractional works · 28.1% of its workBiochemistry, Genetics and Molecular Biology: 14 fractional works · 18.8% of its workMolecular Biology: 12 fractional works · 16.0% of its workBiophysics: 1 fractional works · 0.7% of its workGenetics: 0 fractional works · 0.6% of its workBiochemistry: 0 fractional works · 0.4% of its workCancer Research: 0 fractional works · 0.4% of its workBiotechnology: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.4% of its workImmunology and Microbiology: 3 fractional works · 3.6% of its workImmunology: 2 fractional works · 2.8% of its workMicrobiology: 0 fractional works · 0.6% of its workVirology: 0 fractional works · 0.2% of its workPharmacology, Toxicology and Pharmaceutics: 2 fractional works · 2.8% of its workPharmaceutical Science: 1 fractional works · 1.8% of its workToxicology: 0 fractional works · 0.5% of its workPharmacology: 0 fractional works · 0.5% of its workNeuroscience: 1 fractional works · 1.8% of its workCognitive Neuroscience: 1 fractional works · 1.0% of its workCellular and Molecular Neuroscience: 0 fractional works · 0.4% of its workNeurology: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.1% of its workAgricultural and Biological Sciences: 1 fractional works · 1.0% of its workPlant Science: 1 fractional works · 0.9% of its workSmaller subfields together: 0 fractional works · 0.2% of its workSocial Sciences: 3 fractional works · 3.8% of its workPsychology: 2 fractional works · 2.5% of its workClinical Psychology: 2 fractional works · 2.0% of its workDevelopmental and Educational Psychology: 0 fractional works · 0.2% of its workSocial Psychology: 0 fractional works · 0.2% of its workEconomics, Econometrics and Finance: 1 fractional works · 0.8% of its workEconomics and Econometrics: 1 fractional works · 0.8% of its workSocial Sciences: 0 fractional works · 0.3% of its workCommunication: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.1% of its workBusiness, Management and Accounting: 0 fractional works · 0.2% of its workDecision Sciences: 0 fractional works · 0.1% of its workALL ITS WORKSynthon(Netherlands)76fractional works, all years
Life Sciences28%Physical Sciences37%Health Sciences31%Social Sciences4%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in all years. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 22 fields, with their numbers
    1. Chemistry1621.5%
    2. Engineering67.3%
    3. Materials Science34.1%
    4. Chemical Engineering11.4%
    5. Environmental Science11.3%
    6. Computer Science10.7%
    7. Energy00.4%
    8. Earth and Planetary Sciences00.2%
    9. Physics and Astronomy00.2%
    10. Mathematics00.1%
    1. Medicine2330.7%
    2. Veterinary00.1%
    1. Biochemistry, Genetics and Molecular Biology1418.8%
    2. Immunology and Microbiology33.6%
    3. Pharmacology, Toxicology and Pharmaceutics22.8%
    4. Neuroscience11.8%
    5. Agricultural and Biological Sciences11.0%
    1. Psychology22.5%
    2. Economics, Econometrics and Finance10.8%
    3. Social Sciences00.3%
    4. Business, Management and Accounting00.2%
    5. Decision Sciences00.1%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Biochemistry, Genetics and Molecular Biology: 3.37× its world share, 2 worksBiochemistry, Geneti…Immunology and Microbiology: 8.32× its world share, 1 worksImmunology and Micro…Neuroscience: 7.79× its world share, 1 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 8.56× its world share, 0 worksPharmacology, Toxico…Chemical Engineering: 5.88× its world share, 0 worksChemical EngineeringChemistry: 5.98× its world share, 1 worksChemistryEngineering: 0.57× its world share, 1 worksEngineeringMaterials Science: 0.86× its world share, 0 worksMaterials SciencePhysics and Astronomy: 0.85× its world share, 0 worksPhysics and AstronomyMedicine: 0.93× its world share, 2 worksMedicineDecision Sciences: 0.85× its world share, 0 worksDecision SciencesEconomics, Econometrics and Finance: 0.58× its world share, 0 worksEconomics, Econometr…Psychology: 4.05× its world share, 1 worksPsychologySocial Sciences: 0.06× its world share, 0 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Pharmacology, Toxicology and Pharmaceutics, 8.6×. Every wedge is a field page.

All 14 fields, with their numbers
  1. Pharmacology, Toxicology and Pharmaceutics8.56×0 works
  2. Immunology and Microbiology8.32×1 works
  3. Neuroscience7.79×1 works
  4. Chemistry5.98×1 works
  5. Chemical Engineering5.88×0 works
  6. Psychology4.05×1 works
  7. Biochemistry, Genetics and Molecular Biology3.37×2 works
  8. Medicine0.93×2 works
  9. Materials Science0.86×0 works
  10. Physics and Astronomy0.85×0 works
  11. Decision Sciences0.85×0 works
  12. Economics, Econometrics and Finance0.58×0 works
  13. Engineering0.57×1 works
  14. Social Sciences0.06×0 works

Who are the top researchers at Synthon (Netherlands)?

Ranked on the quality score, Wim H.A. Dokter, Gijs F. M. Verheijden and Patrick H. Beusker lead among researchers whose main affiliation is Synthon (Netherlands).

  1. 1 Wim H.A. Dokter Netherlands · #786,078 worldwide 2.1k citations · 123 works
  2. 2 Gijs F. M. Verheijden Netherlands · #886,844 worldwide 1.3k citations · 42 works
  3. 3 Patrick H. Beusker Netherlands · #899,046 worldwide 1.2k citations · 53 works
  4. 4 Miranda M.C. van der Lee Netherlands · #1,192,613 worldwide 933 citations · 43 works
  5. 5 R. J. Mulder Netherlands · #1,489,663 worldwide 1.2k citations · 18 works
  6. 6 David F. Egging Netherlands · #1,535,645 worldwide 1.2k citations · 38 works
  7. 7 Diels van den Dobbelsteen Netherlands · #1,735,146 worldwide 478 citations · 26 works
  8. 8 Marco Timmers Netherlands · #1,784,962 worldwide 518 citations · 26 works
  9. 9 Gerrit Voortman Netherlands · #2,749,368 worldwide 907 citations · 29 works
All ranked researchers at Synthon (Netherlands)

What are the most cited papers from Synthon (Netherlands)?

The most cited paper from Synthon (Netherlands) is "Trastuzumab duocarmazine in locally advanced and metastatic solid tumours and HER2-expressing breast cancer: a phase 1 dose-escalation and dose-expansion study" (Udai Banerji, Carla M.L. van Herpen, Cristina Saura et al., 2019), with 577 citations. Next come "Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody–Drug Conjugate SYD985" (225) and "The Preclinical Profile of the Duocarmycin-Based HER2-Targeting ADC SYD985 Predicts for Clinical Benefit in Low HER2-Expressing Breast Cancers" (218).

Most cited papers
#PaperReleasedCitations
1 Trastuzumab duocarmazine in locally advanced and metastatic solid tumours and HER2-expressing breast cancer: a phase 1 dose-escalation and dose-expansion study Udai Banerji, Carla M.L. van Herpen, Cristina Saura et al. · The Lancet Oncology Open access 27 Jun 2019 577
2 Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody–Drug Conjugate SYD985 Ronald C. Elgersma, Ruud G. E. Coumans, Tijl Huijbregts et al. · Molecular Pharmaceutics Open access 30 Jan 2015 225
3 The Preclinical Profile of the Duocarmycin-Based HER2-Targeting ADC SYD985 Predicts for Clinical Benefit in Low HER2-Expressing Breast Cancers Miranda M.C. van der Lee, Patrick G. Groothuis, Ruud Ubink et al. · Molecular Cancer Therapeutics 14 Jan 2015 218
4 Preclinical Profile of the HER2-Targeting ADC SYD983/SYD985: Introduction of a New Duocarmycin-Based Linker-Drug Platform Wim H.A. Dokter et al. · Molecular Cancer Therapeutics Open access 5 Sep 2014 168
5 Novel astaxanthin extraction from Haematococcus pluvialis using cell permeabilising ionic liquids Rupali K. Desai, Mathieu Streefland, René H. Wijffels et al. · Green Chemistry Open access 29 Sep 2015 155
All 62 most cited papers, with filters and sorting

Which keywords describe research at Synthon (Netherlands)?

By fractional works in all years, weighted toward what it does more of than the world: Glycosylation, Monoclonal Antibodies, Therapeutic Antibodies, Chemotherapy, Monoclonal Antibody, Antibody Engineering, Fc Receptors and Breast Cancer.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in all years in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Glycosylation8▲ 46×3 topics
  2. Monoclonal Antibodies8▲ 70×3 topics
  3. Therapeutic Antibodies7▲ 71×2 topics
  4. Chemotherapy6▲ 11×5 topics
  5. Monoclonal Antibody6▲ 112×2 topics
  6. Antibody Engineering6▲ 74×1 topic
  7. Fc Receptors6▲ 74×1 topic
  8. Breast Cancer5▲ 25×3 topics
  9. HER25▲ 217×1 topic
  10. Trastuzumab5▲ 154×1 topic
  11. Asymmetric Synthesis3▲ 30×4 topics
  12. Synthesis3▲ 6.9×10 topics
  13. Hydrogen Bonding2▲ 13×3 topics
  14. Medicinal Chemistry2▲ 8.7×5 topics
  15. Organocatalysis2▲ 49×2 topics
  16. PET Imaging2▲ 15×3 topics
  17. Enantioselective Reactions2▲ 34×2 topics
  18. Catalysis2▲ 3.5×8 topics
  19. Biopharmaceuticals2▲ 40×2 topics
  20. Immunogenicity2▲ 53×2 topics
  21. NMR Spectroscopy2▲ 18×3 topics
  22. C-C Bond Formation2▲ 25×1 topic
  23. Chiral Catalysts2▲ 49×1 topic
  24. Chiral Separation2▲ 18×1 topic
  25. Genomic Stability2▲ 24×2 topics
  26. Liquid Chromatography2▲ 15×1 topic
  27. Drug Design2▲ 17×3 topics
  28. Green Chemistry2▲ 7.2×5 topics
  29. Catalyst2▲ 18×2 topics
  30. Chemoselective2▲ 15×2 topics
  31. Magnetic Resonance Imaging2▲ 5.3×2 topics
  32. Crystal Engineering1▲ 16×2 topics
  33. Glycosidase Inhibitors1▲ 37×1 topic
  34. Oligosaccharide Synthesis1▲ 37×1 topic
  35. Dynamic Nuclear Polarization1▲ 25×1 topic
  36. Enantioselective Synthesis1▲ 10×4 topics
  37. Heterocyclic Compounds1▲ 11×3 topics
  38. Protein Aggregation1▲ 22×1 topic
  39. Recombinant Proteins1▲ 32×1 topic
  40. Solid-State NMR1▲ 44×1 topic

Which research topics does Synthon (Netherlands) publish most on?

By volume in 2022-now: Autism Spectrum Disorder Research, Child Abuse and Trauma, Immunotherapy and Immune Responses and Child and Adolescent Psychosocial and Emotional Development.

Autism Spectrum Disorder Research: 0 fractional worksChild Abuse and Trauma: 0 fractional worksImmunotherapy and Immune…0Immunotherapy and Immune Responses: 0 fractional worksChild and Adolescent Psy…0Child and Adolescent Psychosocial and Emotional Development: 0 fractional worksvaccines and immunoinformatics approaches: 0 fractional worksDrug Solubulity and Delivery Systems: 0 fractional worksImmune cells in cancer0Immune cells in cancer: 0 fractional worksAdvanced Polymer Synthesis and Characterization: 0 fractional worksGlycosylation and Glycoproteins Research: 0 fractional worksSARS-CoV-2 and COVID-19 Research: 0 fractional works
Cognitive NeuroscienceClinical PsychologyImmunologyMolecular Biology3 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 Autism Spectrum Disorder Research Cognitive Neuroscience 0 works
  2. 2 Child Abuse and Trauma Clinical Psychology 0 works
  3. 3 Immunotherapy and Immune Responses Immunology 0 works
  4. 4 Child and Adolescent Psychosocial and Emotional Development Clinical Psychology 0 works
  5. 5 vaccines and immunoinformatics approaches Molecular Biology 0 works
  6. 6 Drug Solubulity and Delivery Systems Pharmaceutical Science 0 works
  7. 7 Immune cells in cancer Immunology 0 works
  8. 8 Advanced Polymer Synthesis and Characterization Organic Chemistry 0 works
  9. 9 Glycosylation and Glycoproteins Research Molecular Biology 0 works
  10. 10 SARS-CoV-2 and COVID-19 Research Infectious Diseases 0 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available44.2%not open55.8%

World: 40% of research is openly available.

with international co-authors31.3%domestic only68.7%

World: 18% is written across borders.

How has Synthon (Netherlands)'s research output changed?

Output in 2022-2025 was 31% lower than in 2018-2021.

still counting1990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Synthon (Netherlands) as a percentage of every work published that year, 0.000030% in 2024.

still counting0.00020%0.00040%0.00060%Synthon (Netherlands)0.000024% in 20251990200020102020

Fractional works of Synthon (Netherlands) over all fractional works that year. How the balance of science has shifted.

Other research institutions in Nijmegen

All research institutions in Nijmegen

Research measures only: rankings here say nothing about teaching, admissions or student experience. Comparable institutions and collaboration partners have tabs of their own, above.

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