Genetic Neurodegenerative Diseases
Genetic Neurodegenerative Diseases is a research topic within Cellular and Molecular Neuroscience. Science Explorer counts 39k research works in it since 1950. 15.4% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the molecular mechanisms underlying neurodegenerative diseases such as Huntington's disease, myotonic dystrophy, and ataxias. It focuses on protein aggregation, polyglutamine toxicity, mitochondrial dysfunction, RNA-mediated disorders, chaperone function, gene expression dysregulation, and the role of trinucleotide repeats in neuronal degeneration.
- Huntington's Disease
- Protein Aggregation
- Polyglutamine
- Mitochondrial Dysfunction
- RNA-Mediated Disorders
- Ataxia
- Chaperones
- Gene Expression Dysregulation
- Trinucleotide Repeats
- Neuronal Degeneration
- Research works
- 39k fractional, since 1950
- In the world top 10%
- 6k per year above
- Top-10% rate
- 15.4% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +8% the tick is no change
Which countries lead Genetic Neurodegenerative Diseases research?
By volume, the United States and China publish the most (1.6k and 575 works in 2022–2025).
By volume, 2022–2025
- 1 United States 1.6k works
- 2 China 575 works
- 3 United Kingdom 436 works
- 4 Italy 336 works
- 5 Germany 328 works
- 6 India 327 works
- 7 Japan 311 works
- 8 France 270 works
- 9 Canada 211 works
- 10 Spain 211 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Genetic Neurodegenerative Diseases research?
By volume in 2022–2025, University College London publishes the most Genetic Neurodegenerative Diseases research, followed by Inserm and Cardiff University.
By volume, 2022–2025
- 1 University College LondonUnited Kingdom 50 works
- 2 InsermFrance 30 works
- 3 Cardiff UniversityUnited Kingdom 27 works
- 4 National Institute of Mental Health and NeurosciencesIndia 26 works
- 5 National Hospital for Neurology and NeurosurgeryUnited Kingdom 25 works
- 6 Harvard UniversityUnited States 24 works
- 7 Massachusetts General HospitalUnited States 23 works
- 8 University of PennsylvaniaUnited States 22 works
- 9 Johns Hopkins UniversityUnited States 22 works
- 10 Centre National de la Recherche ScientifiqueFrance 20 works
Who are the leading researchers in Genetic Neurodegenerative Diseases?
The most-cited researchers publishing on Genetic Neurodegenerative Diseases include Susan E. Folstein, Winfried März and P. A. Wijeratne.
- 1 Susan E. Folstein United States 10k citations
- 2 Winfried März Germany 5.2k citations
- 3 P. A. Wijeratne Germany 4.4k citations
- 4 John Hardy United Kingdom 4k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Genetic Neurodegenerative Diseases research done?
The largest centres of Genetic Neurodegenerative Diseases research in 2022–2025 are London (United Kingdom), Paris (France), Beijing (China) and New York (United States). Among places with at least 20 works in it, it is an unusually large share of all research in Nijmegen, Cardiff and Iowa City.
Largest cities, 2022–2025
Where it is the local speciality
- NijmegenNL · 34.4 works8.6×
- CardiffGB · 30.2 works8.6×
- Iowa CityUS · 22.6 works7.1×
- TübingenDE · 22.8 works6.9×
Location quotient: how much more of its research is in Genetic Neurodegenerative Diseases than the world average.
Where is the best place to study Genetic Neurodegenerative Diseases?
Among universities, judged by research, University College London, Innsbruck Medical University and Cardiff University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | University College LondonUnited Kingdom | 59.5 | 18.6% | 6.0× | 50 | +4.9% |
| 2 | Innsbruck Medical UniversityAustria | 50.6 | 20.7% | 15.4× | 9 | -18.2% |
| 3 | Cardiff UniversityUnited Kingdom | 48.1 | 3.9% | 10.8× | 27 | -10.2% |
| 4 | University of OxfordUnited Kingdom | 47.2 | 35.6% | 1.4× | 11 | +51.1% |
| 5 | University of LübeckGermany | 46.8 | 14.9% | 9.9× | 9 | +23.1% |
| 6 | Baylor College of MedicineUnited States | 44.8 | 24.3% | 6.5× | 16 | -36.8% |
| 7 | Harvard UniversityUnited States | 44.6 | 22.2% | 3.2× | 24 | -7.6% |
| 8 | Sorbonne UniversitéFrance | 41.5 | 12.3% | 5.5× | 17 | +21.2% |
| 9 | University of PennsylvaniaUnited States | 41.4 | 20.6% | 4.1× | 22 | -9.8% |
| 10 | Radboud University NijmegenNetherlands | 41.4 | 12.4% | 6.2× | 16 | +1.4% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Genetic Neurodegenerative Diseases research growing?
Output in 2018–2022 was 8% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Genetic Neurodegenerative Diseases.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.