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Topic · Cellular and Molecular Neuroscience

Neuropeptides and Animal Physiology

Neuropeptides and Animal Physiology is a research topic within Cellular and Molecular Neuroscience. Science Explorer counts 67k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the role of neuropeptides and their receptors in various physiological processes and disease states, including stress, anxiety, depression, immune modulation, and cardiovascular function. It covers a wide range of neuropeptides such as opioid receptors, calcitonin gene-related peptide, pituitary adenylate cyclase-activating polypeptide, and vasoactive intestinal peptide.

  • Neuropeptides
  • Receptors
  • Opioid
  • Calcitonin Gene-Related Peptide
  • Pituitary Adenylate Cyclase-Activating Polypeptide
  • Stress
  • Anxiety
  • Depression
  • Immune Modulation
  • Vasoactive Intestinal Peptide
Research works
67k
fractional, since 1950
In the world top 10%
6.6k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-10%
the tick is no change
Largest producer
United States
36% of the 10 largest, 2022-now
Neuropeptides and Animal Physiology

Which countries lead Neuropeptides and Animal Physiology research?

By volume, the United States and China publish the most (1.1k and 870 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.1k works
  2. 2 China 870 works
  3. 3 Japan 241 works
  4. 4 Germany 165 works
  5. 5 India 156 works
  6. 6 United Kingdom 128 works
  7. 7 Italy 120 works
  8. 8 France 95 works
  9. 9 Poland 88 works
  10. 10 Iran 88 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 36.1%China: 28.5%Japan: 7.9%Germany: 5.4%6 others listed: 22.1%36%largest
United States1,103 · 36.1%China870 · 28.5%Japan241 · 7.9%Germany165 · 5.4%6 others listed675 · 22.1%

Shares of the rows listed above, not of the whole node.

Which institutions lead Neuropeptides and Animal Physiology research?

By volume in 2022-now, National Institutes of Health publishes the most Neuropeptides and Animal Physiology research, followed by University of North Carolina at Chapel Hill and Centre National de la Recherche Scientifique.

By volume, 2022-now

  1. 1 National Institutes of HealthUnited States 44 works
  2. 2 University of North Carolina at Chapel HillUnited States 33 works
  3. 3 Centre National de la Recherche ScientifiqueFrance 31 works
  4. 4 Russian Academy of SciencesRussia 31 works
  5. 5 Chinese Academy of SciencesChina 29 works
  6. 6 Harvard UniversityUnited States 25 works
  7. 7 University of MichiganUnited States 25 works
  8. 8 Sichuan UniversityChina 25 works
  9. 9 Shanghai Jiao Tong UniversityChina 24 works
  10. 10 University of CopenhagenDenmark 22 works

Who are the leading researchers in Neuropeptides and Animal Physiology?

The most-cited researchers publishing on Neuropeptides and Animal Physiology include George Davey Smith, Richard M. Ryan and Guido Kroemer.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Richard M. Ryan United States 395k citations
  3. 3 Guido Kroemer France 386k citations
  4. 4 John J.V. McMurray United Kingdom 349k citations
  5. 5 Shizuo Akira Japan 342k citations
  6. 6 Cyrus Cooper United Kingdom 342k citations
  7. 7 Jun Wang China 340k citations
  8. 8 Giuseppe Remuzzi Italy 328k citations
  9. 9 Matthias Mann Germany 308k citations
  10. 10 Dan J. Stein South Africa 306k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Neuropeptides and Animal Physiology?

The most cited paper in Neuropeptides and Animal Physiology is "The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine" (Robert F. Furchgott, John V. Zawadzki, 1980), with 12,123 citations. Next come "Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs" (5,701) and "A simple and very efficient method for generating cDNA libraries" (4,567).

Most cited papers
#PaperReleasedCitations
1 The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine Robert F. Furchgott, John V. Zawadzki · Nature Nov 1980 12,123
2 Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs C. A. Winter, Edwin A. Risley, George W. Nuss · Experimental Biology and Medicine Dec 1962 5,701
3 A simple and very efficient method for generating cDNA libraries Ueli Gubler, Beth J. Hoffman · Gene Nov 1983 4,567
4 Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner Dorothy P. Schafer, Emily K. Lehrman, Amanda G. Kautzman et al. · Neuron Open access May 2012 4,228
5 Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin Wylie Vale, Joachim Spiess, CATHERINE L. RIVIER et al. · Science 18 Sep 1981 3,979
All 100 most cited papers, with filters and sorting

Where is Neuropeptides and Animal Physiology research done?

The largest centres of Neuropeptides and Animal Physiology research in 2022-now are Beijing (China), Shanghai (China), Tokyo (Japan) and Guangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda.

Largest cities, 2022-now

  1. 1 BeijingChina 107 works
  2. 2 ShanghaiChina 87 works
  3. 3 TokyoJapan 56 works
  4. 4 GuangzhouChina 52 works
  5. 5 BethesdaUnited States 44 works
  6. 6 ParisFrance 43 works
  7. 7 New YorkUnited States 43 works
  8. 8 NanjingChina 41 works
  9. 9 TehranIran 38 works
  10. 10 PhiladelphiaUnited States 35 works

Where it is the local speciality

  1. BethesdaUS · 43.9 works8.7×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Neuropeptides and Animal Physiology than the world average.

See Neuropeptides and Animal Physiology on the map

Where is the best place to study Neuropeptides and Animal Physiology?

Among universities, judged by research, University of Toronto, Harvard University and University of Copenhagen score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 19.95%fractional works in this field (log) →share of work in the world top 10% →University of TorontoStanford UniversityUniversity of Copenh…Harvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1University of TorontoCanada 61.233.4%1.9×14 -10.5%
2Harvard UniversityUnited States 59.618.0%2.1×25 -28.4%
3University of CopenhagenDenmark 58.118.7%6.3×22 -30.9%
4Stanford UniversityUnited States 57.520.1%2.4×13 +11.1%
5Sichuan UniversityChina 57.017.7%2.9×24 +46.7%
6Anhui Medical UniversityChina 50.925.6%6.1×10 +63.4%
7Shanghai Jiao Tong UniversityChina 50.316.2%2.2×24 -0.1%
8Washington University in St. LouisUnited States 49.713.7%5.1×13 +35.9%
9University of North Carolina at Chapel HillUnited States 49.38.3%4.9×32 -41.0%
10Duke UniversityUnited States 48.827.8%2.9×9 -30.9%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Neuropeptides and Animal Physiology, country by country

Is Neuropeptides and Animal Physiology research growing?

Output in 2022-2025 was 10% lower than in 2018-2021, peaking in 1994.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Neuropeptides and Animal Physiology as a percentage of every work published that year, 0.017% in 2024.

still counting0.10%0.20%0.30%Neuropeptides and Animal Physiology0.017% in 202519801990200020102020

Fractional works of Neuropeptides and Animal Physiology over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Neuropeptides and Animal Physiology9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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