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Topic · Pathology and Forensic Medicine

Multiple Sclerosis Research Studies

Multiple Sclerosis Research Studies is a research topic within Pathology and Forensic Medicine. Science Explorer counts 37k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the diagnosis, pathogenesis, and treatment of multiple sclerosis (MS) and related disorders such as neuromyelitis optica. It covers topics such as the diagnostic criteria for MS, genetic risk factors, immune mechanisms involved in MS, cognitive impairment, axonal injury, and the autoimmune pathology underlying the disease. The papers also discuss the use of various therapies and their effects on MS patients.

  • Multiple Sclerosis
  • Diagnostic Criteria
  • Neuromyelitis Optica
  • Demyelination
  • Immune Mechanisms
  • Genetic Risk
  • B-Cell Depletion
  • Cognitive Impairment
  • Axonal Injury
  • Autoimmune Pathology
Research works
37k
fractional, since 1950
In the world top 10%
3.7k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+12%
the tick is no change
Largest producer
United States
32% of the 10 largest, 2022-now
Multiple Sclerosis Research Studies

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Multiple Sclerosis Research Studies research?

By volume, the United States and China publish the most (1.9k and 719 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.9k works
  2. 2 China 719 works
  3. 3 Italy 588 works
  4. 4 Germany 496 works
  5. 5 Iran 472 works
  6. 6 United Kingdom 444 works
  7. 7 Spain 322 works
  8. 8 Türkiye 318 works
  9. 9 France 297 works
  10. 10 Canada 275 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 32.3%China: 12.4%Italy: 10.1%Germany: 8.5%6 others listed: 36.7%32%largest
United States1,873 · 32.3%China719 · 12.4%Italy588 · 10.1%Germany496 · 8.5%6 others listed2,127 · 36.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Multiple Sclerosis Research Studies research?

By volume in 2022-now, Harvard University publishes the most Multiple Sclerosis Research Studies research, followed by Tehran University of Medical Sciences and University College London.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 108 works
  2. 2 Tehran University of Medical SciencesIran 83 works
  3. 3 University College LondonUnited Kingdom 58 works
  4. 4 Isfahan University of Medical SciencesIran 57 works
  5. 5 Karolinska InstitutetSweden 55 works
  6. 6 Johns Hopkins UniversityUnited States 54 works
  7. 7 InsermFrance 54 works
  8. 8 University of TorontoCanada 47 works
  9. 9 Mayo ClinicUnited States 47 works
  10. 10 Cleveland ClinicUnited States 44 works

Who are the leading researchers in Multiple Sclerosis Research Studies?

The most-cited researchers publishing on Multiple Sclerosis Research Studies include Christopher J L Murray, Rob Knight and Simon Iain Hay.

  1. 1 Christopher J L Murray United States 583k citations
  2. 2 Rob Knight United States 468k citations
  3. 3 Simon Iain Hay United States 452k citations
  4. 4 Theo Vos United States 439k citations
  5. 5 George Davey Smith United Kingdom 435k citations
  6. 6 Ali H. Mokdad United States 429k citations
  7. 7 Mark J. Daly United States 403k citations
  8. 8 Zulfiqar Ahmed Bhutta Pakistan 371k citations
  9. 9 Jost Bruno Jonas Germany 350k citations
  10. 10 Cyrus Cooper United Kingdom 342k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Multiple Sclerosis Research Studies?

The most cited paper in Multiple Sclerosis Research Studies is "Rating neurologic impairment in multiple sclerosis" (John F. Kurtzke, 1983), with 15,106 citations. Next come "Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria" (9,914) and "Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria" (8,265).

Most cited papers
#PaperReleasedCitations
1 Rating neurologic impairment in multiple sclerosis John F. Kurtzke · Neurology Nov 1983 15,106
2 Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria Chris H. Polman, Stephen C. Reingold, Brenda Banwell et al. · Annals of Neurology Open access 11 Jan 2011 9,914
3 Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria Alan J. Thompson et al. · The Lancet Neurology Open access 21 Dec 2017 8,265
4 New diagnostic criteria for multiple sclerosis: Guidelines for research protocols Charles M. Poser, Donald W. Paty, Labe C. Scheinberg et al. · Annals of Neurology Mar 1983 7,423
5 Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis W. I. McDonald, Alistair Compston, Gilles Edan et al. · Annals of Neurology 26 Jun 2001 6,993
All 97 most cited papers, with filters and sorting

Where is Multiple Sclerosis Research Studies research done?

The largest centres of Multiple Sclerosis Research Studies research in 2022-now are Tehran (Iran), London (United Kingdom), Beijing (China) and Rome (Italy). Among places with at least 20 works in it, it is an unusually large share of all research in Isfahan, Basel and Genoa.

Largest cities, 2022-now

  1. 1 TehranIran 203 works
  2. 2 LondonUnited Kingdom 177 works
  3. 3 BeijingChina 123 works
  4. 4 RomeItaly 113 works
  5. 5 ParisFrance 102 works
  6. 6 New YorkUnited States 100 works
  7. 7 BostonUnited States 90 works
  8. 8 MilanItaly 89 works
  9. 9 IstanbulTürkiye 87 works
  10. 10 MelbourneAustralia 83 works

Where it is the local speciality

  1. IsfahanIR · 65.8 works12×
  2. BaselCH · 58.2 works10×
  3. GenoaIT · 47.9 works9.4×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Multiple Sclerosis Research Studies than the world average.

See Multiple Sclerosis Research Studies on the map

Where is the best place to study Multiple Sclerosis Research Studies?

Among universities, judged by research, Karolinska Institutet, University College London and Harvard University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 20.06%fractional works in this field (log) →share of work in the world top 10% →The University of Sy…University College L…Karolinska InstitutetHarvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Karolinska InstitutetSweden 79.619.7%12.1×55 +2.4%
2University College LondonUnited Kingdom 78.021.8%4.5×58 -3.3%
3Harvard UniversityUnited States 77.313.8%4.2×108 +10.0%
4The University of SydneyAustralia 74.923.3%3.7×36 +23.8%
5University of AmsterdamNetherlands 71.622.9%5.7×27 +0.1%
6Medical University of ViennaAustria 70.516.7%10.8×28 +17.7%
7Johns Hopkins UniversityUnited States 68.718.1%4.4×54 -8.2%
8Vrije Universiteit AmsterdamNetherlands 68.622.0%5.7×18 +8.8%
9Universitat Autònoma de BarcelonaSpain 68.520.6%4.8×25 +20.8%
10University of ZurichSwitzerland 67.121.7%3.5×20 +14.2%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Multiple Sclerosis Research Studies, country by country

Is Multiple Sclerosis Research Studies research growing?

Output in 2022-2025 was 12% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Multiple Sclerosis Research Studies.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Multiple Sclerosis Research Studies as a percentage of every work published that year, 0.036% in 2024.

still counting0.020%0.040%0.060%Multiple Sclerosis Research Studies0.037% in 202519801990200020102020

Fractional works of Multiple Sclerosis Research Studies over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Multiple Sclerosis Research Studies9.9% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Questions people ask

Who is researching a cure for multiple sclerosis?

By volume in 2022-now, Harvard University publishes the most Multiple Sclerosis Research Studies research, followed by Tehran University of Medical Sciences and University College London. By volume, the United States and China publish the most (1.9k and 719 works in 2022-now).

How much research is there on multiple sclerosis, and is it growing?

Output in 2022-2025 was 12% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Multiple Sclerosis Research Studies.

Is Multiple Sclerosis Research Studies research growing?
All 1,273 questions in the Question Catalogue

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