Receptor Mechanisms and Signaling
Receptor Mechanisms and Signaling is a research topic within Molecular Biology. Science Explorer counts 88k research works in it since 1950. 18.3% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the structure, function, and signaling mechanisms of G protein-coupled receptors (GPCRs), with a focus on crystal structures, signal transduction, arrestin-mediated pathways, pharmacology, drug discovery, receptor activation, biased signaling, and the molecular mechanisms involved. The research covers a wide range of topics related to GPCRs and their implications in various biological processes.
- Crystal Structure
- G-Protein-Coupled Receptors
- Signal Transduction
- Arrestin
- Pharmacology
- Drug Discovery
- Receptor Activation
- Biased Signaling
- Cell Signaling
- Molecular Mechanisms
- Research works
- 88k fractional, since 1950
- In the world top 10%
- 16k per year above
- Top-10% rate
- 18.3% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- -10% the tick is no change
Which countries lead Receptor Mechanisms and Signaling research?
By volume, the United States and China publish the most (1.9k and 845 works in 2022–2025).
By volume, 2022–2025
- 1 United States 1.9k works
- 2 China 845 works
- 3 Germany 307 works
- 4 Japan 297 works
- 5 United Kingdom 226 works
- 6 India 195 works
- 7 France 164 works
- 8 Italy 158 works
- 9 Canada 140 works
- 10 Russia 110 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Receptor Mechanisms and Signaling research?
By volume in 2022–2025, University of North Carolina at Chapel Hill publishes the most Receptor Mechanisms and Signaling research, followed by Vanderbilt University and University of California, Davis.
By volume, 2022–2025
- 1 University of North Carolina at Chapel HillUnited States 58 works
- 2 Vanderbilt UniversityUnited States 31 works
- 3 University of California, DavisUnited States 30 works
- 4 University of MichiganUnited States 29 works
- 5 University of PittsburghUnited States 29 works
- 6 University of CopenhagenDenmark 24 works
- 7 National Institutes of HealthUnited States 23 works
- 8 Washington University in St. LouisUnited States 22 works
- 9 Centre National de la Recherche ScientifiqueFrance 21 works
- 10 University of California San DiegoUnited States 21 works
Who are the leading researchers in Receptor Mechanisms and Signaling?
The most-cited researchers publishing on Receptor Mechanisms and Signaling include John J. McGrath and Paul H. Lee.
- 1 John J. McGrath Australia 5.3k citations
- 2 Paul H. Lee Hong Kong 4.3k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Receptor Mechanisms and Signaling research done?
The largest centres of Receptor Mechanisms and Signaling research in 2022–2025 are Beijing (China), Shanghai (China), New York (United States) and Tokyo (Japan). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda, Nashville and Davis.
Largest cities, 2022–2025
- 1 Beijing China 140 works
- 2 Shanghai China 104 works
- 3 New York United States 96 works
- 4 Tokyo Japan 85 works
- 5 Paris France 75 works
- 6 Bethesda United States 71 works
- 7 Chapel Hill United States 62 works
- 8 Philadelphia United States 59 works
- 9 London United Kingdom 52 works
- 10 Seoul South Korea 51 works
Where it is the local speciality
- BethesdaUS · 71.4 works11×
- NashvilleUS · 44.9 works8.9×
- DavisUS · 30.4 works7.4×
- Chapel HillUS · 61.7 works6.5×
Location quotient: how much more of its research is in Receptor Mechanisms and Signaling than the world average.
Where is the best place to study Receptor Mechanisms and Signaling?
Among universities, judged by research, ShanghaiTech University, University of Copenhagen and Vanderbilt University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | ShanghaiTech UniversityChina | 55.8 | 37.6% | 12.1× | 12 | — |
| 2 | University of CopenhagenDenmark | 49.1 | 24.6% | 6.7× | 24 | +0.3% |
| 3 | Vanderbilt UniversityUnited States | 48.5 | 14.3% | 14.3× | 31 | -15.8% |
| 4 | Leipzig UniversityGermany | 47.9 | 20.5% | 10.2× | 15 | +5.9% |
| 5 | University of California, DavisUnited States | 46.2 | 18.3% | 7.6× | 30 | +6.4% |
| 6 | University of North Carolina at Chapel HillUnited States | 44.0 | 10.8% | 6.4× | 58 | +23.4% |
| 7 | Karolinska InstitutetSweden | 43.8 | 14.5% | 7.3× | 17 | -12.8% |
| 8 | University of Chinese Academy of SciencesChina | 43.4 | 39.6% | 1.6× | 14 | +252.3% |
| 9 | Medical College of WisconsinUnited States | 42.8 | 12.2% | 11.3× | 15 | +37.3% |
| 10 | Temple UniversityUnited States | 40.8 | 8.1% | 11.7× | 16 | +5.2% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Receptor Mechanisms and Signaling research growing?
Output in 2018–2022 was 10% lower than in 2013–2017, peaking in 2008.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.