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Topic · Organic Chemistry

Catalytic Cross-Coupling Reactions

Catalytic Cross-Coupling Reactions is a research topic within Organic Chemistry. Science Explorer counts 34k research works in it since 1952. 9.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the advances in transition metal-catalyzed cross-coupling reactions, particularly palladium-catalyzed processes, for organic synthesis. It covers topics such as C-C bond formation, homogeneous and heterogeneous catalysis, aryl halides, Suzuki-Miyaura and Heck reactions, and the use of nickel as a catalyst.

  • Palladium-Catalyzed
  • Cross-Coupling Reactions
  • Transition Metal Catalysis
  • Organic Synthesis
  • C-C Bond Formation
  • Homogeneous and Heterogeneous Catalysis
  • Aryl Halides
  • Suzuki-Miyaura Reaction
  • Heck Reaction
  • Nickel-Catalyzed
Research works
34k
fractional, since 1952
In the world top 10%
3.3k
per year above
Top-10% rate
9.8%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-9%
the tick is no change
Largest producer
China
44% of the 10 largest, 2022-now
Catalytic Cross-Coupling Reactions

Which countries lead Catalytic Cross-Coupling Reactions research?

By volume, China and India publish the most (1.8k and 620 works in 2022-now).

By volume, 2022-now

  1. 1 China 1.8k works
  2. 2 India 620 works
  3. 3 United States 493 works
  4. 4 Japan 288 works
  5. 5 Germany 285 works
  6. 6 France 169 works
  7. 7 Russia 131 works
  8. 8 Iran 118 works
  9. 9 United Kingdom 118 works
  10. 10 Spain 109 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 43.8%India: 15.0%United States: 11.9%Japan: 6.9%6 others listed: 22.4%44%largest
China1,817 · 43.8%India620 · 15.0%United States493 · 11.9%Japan288 · 6.9%6 others listed930 · 22.4%

Shares of the rows listed above, not of the whole node.

Which institutions lead Catalytic Cross-Coupling Reactions research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most Catalytic Cross-Coupling Reactions research, followed by Centre National de la Recherche Scientifique and Russian Academy of Sciences.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 154 works
  2. 2 Centre National de la Recherche ScientifiqueFrance 93 works
  3. 3 Russian Academy of SciencesRussia 65 works
  4. 4 University of Chinese Academy of SciencesChina 41 works
  5. 5 Nankai UniversityChina 40 works
  6. 6 Council of Scientific and Industrial ResearchIndia 39 works
  7. 7 Sichuan UniversityChina 37 works
  8. 8 Academy of Scientific and Innovative ResearchIndia 30 works
  9. 9 The University of OsakaJapan 29 works
  10. 10 Zhengzhou UniversityChina 28 works

Who are the leading researchers in Catalytic Cross-Coupling Reactions?

The most-cited researchers publishing on Catalytic Cross-Coupling Reactions include Michaël Grätzel, George M. Whitesides and Wei Huang.

  1. 1 Michaël Grätzel Switzerland 458k citations
  2. 2 George M. Whitesides United States 267k citations
  3. 3 Wei Huang China 267k citations
  4. 4 Ben Zhong Tang China 261k citations
  5. 5 Stefan Grimme Germany 224k citations
  6. 6 Kai You Wang China 224k citations
  7. 7 George M. Sheldrick Germany 220k citations
  8. 8 Zhenan Bao United States 187k citations
  9. 9 Richard Henry Friend United Kingdom 185k citations
  10. 10 Markus Antonietti Germany 185k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Catalytic Cross-Coupling Reactions?

The most cited paper in Catalytic Cross-Coupling Reactions is "Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds" (Norio Miyaura, Akira Suzuki, 1995), with 12,838 citations. Next come "Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions" (6,127) and "An overview of N-heterocyclic carbenes" (4,281).

Most cited papers
#PaperReleasedCitations
1 Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds Norio Miyaura, Akira Suzuki · Chemical Reviews Open access Nov 1995 12,838
2 Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions Thomas W. Lyons, Melanie Sarah Sanford · Chemical Reviews ReviewOpen access 15 Jan 2010 6,127
3 An overview of N-heterocyclic carbenes Matthew N. Hopkinson, Christian Paolo Richter, Michael Schedler et al. · Nature Jun 2014 4,281
4 Palladium(II)‐Catalyzed CH Activation/CC Cross‐Coupling Reactions: Versatility and Practicality Xiao Chen, Keary M. Engle, Dong‐Hui Wang et al. · Angewandte Chemie International Edition Open access 25 Jun 2009 4,122
5 The Heck Reaction as a Sharpening Stone of Palladium Catalysis I. P. Beletskaya, Andrei V. Cheprakov · Chemical Reviews Review 21 Jul 2000 3,914
All 98 most cited papers, with filters and sorting

Where is Catalytic Cross-Coupling Reactions research done?

The largest centres of Catalytic Cross-Coupling Reactions research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Hangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Xinxiang and Ghaziabad.

Largest cities, 2022-now

  1. 1 BeijingChina 223 works
  2. 2 ShanghaiChina 161 works
  3. 3 GuangzhouChina 88 works
  4. 4 HangzhouChina 82 works
  5. 5 NanjingChina 80 works
  6. 6 TokyoJapan 76 works
  7. 7 TianjinChina 74 works
  8. 8 ParisFrance 62 works
  9. 9 ChengduChina 60 works
  10. 10 MoscowRussia 57 works

Where it is the local speciality

  1. XinxiangCN · 26.1 works19×
  2. GhaziabadIN · 30.3 works13×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Catalytic Cross-Coupling Reactions than the world average.

See Catalytic Cross-Coupling Reactions on the map

Where is the best place to study Catalytic Cross-Coupling Reactions?

Among universities, judged by research, Southern University of Science and Technology, Nankai University and University of Chinese Academy of Sciences score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 22.41%fractional works in this field (log) →share of work in the world top 10% →Southern University …Nankai UniversityUniversity of Chines…Henan Normal Univers…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Southern University of Science and TechnologyChina 79.426.4%11.5×26 +113.5%
2Nankai UniversityChina 76.425.6%13.8×40 +16.2%
3University of Chinese Academy of SciencesChina 70.320.2%5.9×41 +3.5%
4Henan Normal UniversityChina 61.017.5%29.8×25 +160.4%
5Lanzhou UniversityChina 58.424.3%9.0×26 -8.1%
6Sichuan UniversityChina 56.612.7%3.9×37 +3.0%
7Princeton UniversityUnited States 53.931.5%4.8×9 -16.3%
8Zhengzhou UniversityChina 53.516.8%5.5×28 +4.6%
9Wuhan UniversityChina 53.025.6%3.1×18 -8.3%
10RWTH Aachen UniversityGermany 52.323.5%4.8×16 -41.0%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Catalytic Cross-Coupling Reactions, country by country

Is Catalytic Cross-Coupling Reactions research growing?

Output in 2022-2025 was 9% lower than in 2018-2021, peaking in 2015.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Catalytic Cross-Coupling Reactions as a percentage of every work published that year, 0.018% in 2024.

still counting0.020%0.040%0.060%Catalytic Cross-Coupling Reactions0.019% in 202519801990200020102020

Fractional works of Catalytic Cross-Coupling Reactions over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Catalytic Cross-Coupling Reactions9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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