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Topic · Molecular Biology

Hedgehog Signaling Pathway Studies

Hedgehog Signaling Pathway Studies is a research topic within Molecular Biology. Science Explorer counts 20k research works in it since 1950. 17.4% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the role of Hedgehog signaling in both animal development and cancer, particularly its involvement in tumorigenesis, stem cell renewal, and the progression of specific cancers such as pancreatic cancer and basal cell carcinoma. The papers also discuss the mechanisms of Hedgehog pathway inhibition and its potential as a therapeutic target for cancer treatment.

  • Hedgehog Signaling
  • Cancer
  • Development
  • Pathway Inhibition
  • Tumorigenesis
  • Stem Cells
  • Pancreatic Cancer
  • Gli Proteins
  • Smoothened
  • Basal Cell Carcinoma
Research works
20k
fractional, since 1950
In the world top 10%
3.4k
per year above
Top-10% rate
17.4%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
-2%
the tick is no change

Which countries lead Hedgehog Signaling Pathway Studies research?

By volume, the United States and China publish the most (579 and 519 works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 579 works
  2. 2 China 519 works
  3. 3 India 227 works
  4. 4 Japan 137 works
  5. 5 Italy 112 works
  6. 6 Germany 88 works
  7. 7 United Kingdom 86 works
  8. 8 France 79 works
  9. 9 Brazil 71 works
  10. 10 Spain 68 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 29.5%China: 26.4%India: 11.6%Japan: 7.0%6 others listed: 25.6%29%largest
United States579 · 29.5%China519 · 26.4%India227 · 11.6%Japan137 · 7.0%6 others listed503 · 25.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Hedgehog Signaling Pathway Studies research?

By volume in 2022–2025, Harvard University publishes the most Hedgehog Signaling Pathway Studies research, followed by Inserm and Yale University.

By volume, 2022–2025

  1. 1 Harvard UniversityUnited States 10 works
  2. 2 InsermFrance 9 works
  3. 3 Yale UniversityUnited States 9 works
  4. 4 University of California, Los AngelesUnited States 9 works
  5. 5 Sichuan UniversityChina 8 works
  6. 6 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 8 works
  7. 7 Stanford UniversityUnited States 8 works
  8. 8 University of MichiganUnited States 8 works
  9. 9 All India Institute of Medical SciencesIndia 8 works
  10. 10 The University of Texas MD Anderson Cancer CenterUnited States 8 works

Who are the leading researchers in Hedgehog Signaling Pathway Studies?

The most-cited researchers publishing on Hedgehog Signaling Pathway Studies include Caroline Robert, A.G. Evans and Thomas Schwarz.

  1. 1 Caroline Robert France 3.3k citations
  2. 2 A.G. Evans United States 3.2k citations
  3. 3 Thomas Schwarz United States 3.1k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Hedgehog Signaling Pathway Studies research done?

The largest centres of Hedgehog Signaling Pathway Studies research in 2022–2025 are Beijing (China), Shanghai (China), Tokyo (Japan) and Paris (France).

Largest cities, 2022–2025

  1. 1 Beijing China 63 works
  2. 2 Shanghai China 47 works
  3. 3 Tokyo Japan 37 works
  4. 4 Paris France 33 works
  5. 5 Guangzhou China 29 works
  6. 6 London United Kingdom 27 works
  7. 7 Rome Italy 24 works
  8. 8 Hangzhou China 23 works
  9. 9 New York United States 23 works
  10. 10 Seoul South Korea 23 works
See Hedgehog Signaling Pathway Studies on the map

Where is the best place to study Hedgehog Signaling Pathway Studies?

Among universities, judged by research, Harvard University, Sichuan University and Yale University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 15.7167%fractional works in this node (log) →share in the world top 10% →Harvard University: 10, 24.8%Sichuan University: 8, 21.2%Yale University: 9, 16.2%Stanford University: 8, 19.1%Chinese Academy of Medical Sciences & Peking Union Medical College: 8, 11.1%University of California, Los Angeles: 9, 1.9%Harvard UniversitySichuan UniversityStanford UniversityYale University
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Harvard UniversityUnited States 69.024.8%3.2×10 -13.2%
2 Sichuan UniversityChina 43.221.2%1.9×8 +62.2%
3 Yale UniversityUnited States 42.216.2%3.4×9 -6.8%
4 Stanford UniversityUnited States 34.219.1%2.6×8 -11.4%
5 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 30.111.1%3.3×8 +9.2%
6 University of California, Los AngelesUnited States 18.31.9%3.5×9 -28.5%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Hedgehog Signaling Pathway Studies research growing?

Output in 2018–2022 was 2% lower than in 2013–2017, peaking in 2015. The fastest-growing topics are Hedgehog Signaling Pathway Studies.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.