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Topic · Immunology

Immunodeficiency and Autoimmune Disorders

Immunodeficiency and Autoimmune Disorders is a research topic within Immunology. Science Explorer counts 45k research works in it since 1950. 12.3% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the genetic basis and clinical manifestations of primary immunodeficiency disorders, including immune dysregulation, Th17 cell deficiency, common variable immunodeficiency, and defects in the interferon-? pathway. It also discusses the use of hematopoietic stem cell transplantation and immunoglobulin replacement therapy in the management of these disorders.

  • Primary Immunodeficiency
  • Genetic Mutations
  • Immune Dysregulation
  • Human Inborn Errors
  • Th17 Cell Deficiency
  • Common Variable Immunodeficiency
  • Hematopoietic Stem Cell Transplantation
  • Interferon-? Pathway Defects
  • B Cell Abnormalities
  • Immunoglobulin Replacement Therapy
Research works
45k
fractional, since 1950
In the world top 10%
5.5k
per year above
Top-10% rate
12.3%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+20%
the tick is no change

Which countries lead Immunodeficiency and Autoimmune Disorders research?

By volume, the United States and China publish the most (1.6k and 600 works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 1.6k works
  2. 2 China 600 works
  3. 3 United Kingdom 306 works
  4. 4 Germany 303 works
  5. 5 Italy 280 works
  6. 6 France 278 works
  7. 7 Japan 275 works
  8. 8 India 261 works
  9. 9 Spain 236 works
  10. 10 Türkiye 159 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 37.4%China: 13.9%United Kingdom: 7.1%Germany: 7.0%6 others listed: 34.6%37%largest
United States1,612 · 37.4%China600 · 13.9%United Kingdom306 · 7.1%Germany303 · 7.0%6 others listed1,489 · 34.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Immunodeficiency and Autoimmune Disorders research?

By volume in 2022–2025, Inserm publishes the most Immunodeficiency and Autoimmune Disorders research, followed by Harvard University and University of North Carolina at Chapel Hill.

Who are the leading researchers in Immunodeficiency and Autoimmune Disorders?

The most-cited researchers publishing on Immunodeficiency and Autoimmune Disorders include Winfried März and Hagop M. Kantarjian.

  1. 1 Winfried März Germany 5.2k citations
  2. 2 Hagop M. Kantarjian United States 4k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Immunodeficiency and Autoimmune Disorders research done?

The largest centres of Immunodeficiency and Autoimmune Disorders research in 2022–2025 are Paris (France), Beijing (China), London (United Kingdom) and New York (United States). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda and Freiburg.

Largest cities, 2022–2025

  1. 1 Paris France 134 works
  2. 2 Beijing China 120 works
  3. 3 London United Kingdom 107 works
  4. 4 New York United States 94 works
  5. 5 Tokyo Japan 83 works
  6. 6 Moscow Russia 75 works
  7. 7 Boston United States 71 works
  8. 8 Bethesda United States 71 works
  9. 9 Madrid Spain 69 works
  10. 10 Rome Italy 64 works

Where it is the local speciality

  1. BethesdaUS · 70.8 works9.4×
  2. FreiburgDE · 21.8 works5.6×
← less than its size predictsmore →

Location quotient: how much more of its research is in Immunodeficiency and Autoimmune Disorders than the world average.

See Immunodeficiency and Autoimmune Disorders on the map

Where is the best place to study Immunodeficiency and Autoimmune Disorders?

Among universities, judged by research, Harvard University, Karolinska Institutet and Post Graduate Institute of Medical Education and Research score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 16.65%fractional works in this node (log) →share in the world top 10% →Harvard University: 23, 23.3%Karolinska Institutet: 15, 18.3%Post Graduate Institute of Medical Education and Research: 16, 8.5%Université Paris Cité: 15, 18.9%Medizinische Hochschule Hannover: 12, 15.7%Washington University in St. Louis: 14, 20.0%Icahn School of Medicine at Mount Sinai: 18, 14.1%Chinese Academy of Medical Sciences & Peking Union Medical College: 21, 16.3%Baylor College of Medicine: 13, 16.8%University College London: 19, 14.6%Harvard UniversityUniversité Paris CitéKarolinska InstitutetPost Graduate Instit…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Harvard UniversityUnited States 64.223.3%3.0×23 +24.9%
2 Karolinska InstitutetSweden 59.118.3%5.6×15 +8.0%
3 Post Graduate Institute of Medical Education and ResearchIndia 55.38.5%7.9×16 +175.8%
4 Université Paris CitéFrance 55.218.9%5.7×15 -8.8%
5 Medizinische Hochschule HannoverGermany 54.615.7%9.5×12 -12.4%
6 Washington University in St. LouisUnited States 53.120.0%3.4×14 +97.3%
7 Icahn School of Medicine at Mount SinaiUnited States 52.014.1%6.2×18 +8.2%
8 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 50.816.3%3.5×21 +44.0%
9 Baylor College of MedicineUnited States 49.116.8%5.2×13 +64.8%
10 University College LondonUnited Kingdom 48.114.6%2.3×19 +16.0%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Immunodeficiency and Autoimmune Disorders research growing?

Output in 2018–2022 was 20% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Immunodeficiency and Autoimmune Disorders.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.