Complement system in diseases
Complement system in diseases is a research topic within Immunology. Science Explorer counts 24k research works in it since 1950. 18.1% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the role of the complement system in immune response, focusing on its involvement in thrombotic microangiopathies, hemolytic uremic syndrome, and inflammatory diseases. It delves into the genetics, regulation, and therapeutic interventions such as Eculizumab for managing complement-related disorders.
- Complement
- Immune
- Thrombotic Microangiopathies
- Hemolytic Uremic Syndrome
- Eculizumab
- Innate Immunity
- ADAMTS13
- Regulation
- Inflammatory Diseases
- Genetics
- Research works
- 24k fractional, since 1950
- In the world top 10%
- 4.3k per year above
- Top-10% rate
- 18.1% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +17% the tick is no change
Which countries lead Complement system in diseases research?
By volume, the United States and China publish the most (985 and 473 works in 2022–2025).
By volume, 2022–2025
- 1 United States 985 works
- 2 China 473 works
- 3 United Kingdom 181 works
- 4 Japan 179 works
- 5 Germany 168 works
- 6 France 163 works
- 7 India 158 works
- 8 Italy 131 works
- 9 Spain 101 works
- 10 Canada 78 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Complement system in diseases research?
By volume in 2022–2025, Chinese Academy of Medical Sciences & Peking Union Medical College publishes the most Complement system in diseases research, followed by Inserm and Apellis Pharmaceuticals (United States).
By volume, 2022–2025
- 1 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 16 works
- 2 InsermFrance 15 works
- 3 Apellis Pharmaceuticals (United States)United States 13 works
- 4 Washington University in St. LouisUnited States 13 works
- 5 Johns Hopkins UniversityUnited States 12 works
- 6 Nara Medical UniversityJapan 12 works
- 7 Peking UniversityChina 11 works
- 8 Harvard UniversityUnited States 11 works
- 9 Semmelweis UniversityHungary 11 works
- 10 Cleveland ClinicUnited States 11 works
Who are the leading researchers in Complement system in diseases?
The most-cited researchers publishing on Complement system in diseases include Giuseppe Remuzzi.
- 1 Giuseppe Remuzzi Italy 8.1k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Complement system in diseases research done?
The largest centres of Complement system in diseases research in 2022–2025 are Paris (France), Beijing (China), London (United Kingdom) and New York (United States). Among places with at least 20 works in it, it is an unusually large share of all research in Basel.
Largest cities, 2022–2025
Where it is the local speciality
- BaselCH · 21.8 works10×
Location quotient: how much more of its research is in Complement system in diseases than the world average.
Where is the best place to study Complement system in diseases?
Among universities, judged by research, Semmelweis University, Medical University of Vienna and Université Paris Cité score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Semmelweis UniversityHungary | 60.0 | 13.5% | 16.5× | 11 | +78.6% |
| 2 | Medical University of ViennaAustria | 56.9 | 19.6% | 9.2× | 10 | +7.5% |
| 3 | Université Paris CitéFrance | 55.9 | 28.4% | 6.3× | 9 | +7.5% |
| 4 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 50.4 | 9.9% | 4.8× | 16 | +106.1% |
| 5 | Washington University in St. LouisUnited States | 48.4 | 24.3% | 5.2× | 13 | -22.2% |
| 6 | Nara Medical UniversityJapan | 45.3 | 9.0% | 51.0× | 12 | +10.6% |
| 7 | Lund UniversitySweden | 43.4 | 21.6% | 4.4× | 9 | +17.0% |
| 8 | University of IowaUnited States | 42.2 | 24.1% | 6.6× | 10 | -52.7% |
| 9 | Harvard UniversityUnited States | 41.4 | 23.5% | 2.5× | 11 | -24.1% |
| 10 | Duke UniversityUnited States | 40.9 | 27.2% | 3.5× | 8 | +35.0% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Complement system in diseases research growing?
Output in 2018–2022 was 17% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Complement system in diseases.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.