Histone Deacetylase Inhibitors Research
Histone Deacetylase Inhibitors Research is a research topic within Molecular Biology. Science Explorer counts 21k research works in it since 1953. 22.5% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the role of histone deacetylases (HDACs) in regulating cellular functions, gene expression, and epigenetic modifications. It covers the use of HDAC inhibitors in cancer therapy, their impact on neurodegenerative disorders, and their involvement in protein complexes and enzymatic activity.
- Histone Deacetylases
- HDAC Inhibitors
- Epigenetic Regulation
- Cancer Therapy
- Cellular Functions
- Acetylation
- Gene Expression
- Neurodegenerative Disorders
- Protein Complexes
- Enzymatic Activity
- Research works
- 21k fractional, since 1953
- In the world top 10%
- 4.8k per year above
- Top-10% rate
- 22.5% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- +15% the tick is no change
Which countries lead Histone Deacetylase Inhibitors Research research?
By volume, China and the United States publish the most (1.5k and 1.1k works in 2022–2025).
By volume, 2022–2025
- 1 China 1.5k works
- 2 United States 1.1k works
- 3 India 242 works
- 4 Germany 176 works
- 5 Italy 161 works
- 6 Japan 139 works
- 7 South Korea 136 works
- 8 United Kingdom 102 works
- 9 France 76 works
- 10 Canada 74 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Histone Deacetylase Inhibitors Research research?
By volume in 2022–2025, The University of Texas MD Anderson Cancer Center publishes the most Histone Deacetylase Inhibitors Research research, followed by Chinese Academy of Medical Sciences & Peking Union Medical College and Sichuan University.
By volume, 2022–2025
- 1 The University of Texas MD Anderson Cancer CenterUnited States 50 works
- 2 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 28 works
- 3 Sichuan UniversityChina 26 works
- 4 Sun Yat-sen UniversityChina 23 works
- 5 China Pharmaceutical UniversityChina 20 works
- 6 China Medical UniversityChina 19 works
- 7 Zhejiang UniversityChina 18 works
- 8 Soochow UniversityChina 17 works
- 9 Zhengzhou UniversityChina 17 works
- 10 University of North Carolina at Chapel HillUnited States 16 works
Who are the leading researchers in Histone Deacetylase Inhibitors Research?
The most-cited researchers publishing on Histone Deacetylase Inhibitors Research include Hagop M. Kantarjian and Gordon B. Mills.
- 1 Hagop M. Kantarjian United States 4k citations
- 2 Gordon B. Mills United States 3.7k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Histone Deacetylase Inhibitors Research research done?
The largest centres of Histone Deacetylase Inhibitors Research research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Houston.
Largest cities, 2022–2025
Where it is the local speciality
- HoustonUS · 69.0 works6.3×
Location quotient: how much more of its research is in Histone Deacetylase Inhibitors Research than the world average.
Where is the best place to study Histone Deacetylase Inhibitors Research?
Among universities, judged by research, China Medical University, China Pharmaceutical University and Sichuan University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | China Medical UniversityChina | 70.7 | 41.2% | 13.3× | 19 | +58.6% |
| 2 | China Pharmaceutical UniversityChina | 69.4 | 37.8% | 21.7× | 20 | +75.0% |
| 3 | Sichuan UniversityChina | 59.0 | 33.5% | 3.5× | 26 | +239.5% |
| 4 | Shandong First Medical UniversityChina | 58.1 | 41.2% | 8.1× | 9 | — |
| 5 | Zhengzhou UniversityChina | 56.3 | 33.3% | 4.3× | 16 | +296.0% |
| 6 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 55.3 | 28.6% | 6.6× | 28 | +63.2% |
| 7 | University of BonnGermany | 51.5 | 41.5% | 5.4× | 8 | -12.8% |
| 8 | Sun Yat-sen UniversityChina | 48.6 | 30.4% | 3.3× | 23 | +97.9% |
| 9 | Nanjing University of Chinese MedicineChina | 47.2 | 23.4% | 10.3× | 11 | — |
| 10 | Shenyang Pharmaceutical UniversityChina | 45.7 | 22.1% | 19.4× | 11 | — |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Histone Deacetylase Inhibitors Research research growing?
Output in 2018–2022 was 15% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Histone Deacetylase Inhibitors Research.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.