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Topic · Molecular Biology

Biochemical and Structural Characterization

Biochemical and Structural Characterization is a research topic within Molecular Biology. Science Explorer counts 21k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the bioengineering and protein anchoring mechanisms of cyclotides, sortase-mediated protein ligation, and the assembly of pili in Gram-positive bacteria. It explores the use of peptide tags, bacterial adhesins, and isopeptide bonds for protein engineering, as well as the enzymatic stability and bioactive properties of cyclotides.

  • Cyclotides
  • Sortase
  • Protein Engineering
  • Peptide Tag
  • Bacterial Adhesin
  • Pili Assembly
  • Isopeptide Bonds
  • Macrocyclization
  • Gram-Positive Bacteria
  • Enzymatic Stability
Research works
21k
fractional, since 1950
In the world top 10%
2.1k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+8%
the tick is no change
Largest producer
China
29% of the 10 largest, 2022-now
Biochemical and Structural Characterization

Which countries lead Biochemical and Structural Characterization research?

By volume, China and the United States publish the most (684 and 535 works in 2022-now).

By volume, 2022-now

  1. 1 China 684 works
  2. 2 United States 535 works
  3. 3 India 360 works
  4. 4 Indonesia 189 works
  5. 5 Germany 134 works
  6. 6 Brazil 105 works
  7. 7 United Kingdom 105 works
  8. 8 Japan 95 works
  9. 9 Russia 82 works
  10. 10 Iran 75 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 28.9%United States: 22.6%India: 15.2%Indonesia: 8.0%6 others listed: 25.2%29%largest
China684 · 28.9%United States535 · 22.6%India360 · 15.2%Indonesia189 · 8.0%6 others listed597 · 25.2%

Shares of the rows listed above, not of the whole node.

Which institutions lead Biochemical and Structural Characterization research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Biochemical and Structural Characterization research, followed by Chinese Academy of Sciences and Centre National de la Recherche Scientifique.

By volume, 2022-now

  1. 1 Russian Academy of SciencesRussia 38 works
  2. 2 Chinese Academy of SciencesChina 34 works
  3. 3 Centre National de la Recherche ScientifiqueFrance 30 works
  4. 4 Udayana UniversityIndonesia 19 works
  5. 5 Chinese Academy of Agricultural SciencesChina 19 works
  6. 6 The University of QueenslandAustralia 17 works
  7. 7 National Institutes of HealthUnited States 13 works
  8. 8 Council of Scientific and Industrial ResearchIndia 12 works
  9. 9 Zhejiang UniversityChina 12 works
  10. 10 Harvard UniversityUnited States 11 works

Who are the leading researchers in Biochemical and Structural Characterization?

The most-cited researchers publishing on Biochemical and Structural Characterization include Peer Bork, Róbert Langer and John Q. Trojanowski.

  1. 1 Peer Bork Germany 396k citations
  2. 2 Róbert Langer United States 303k citations
  3. 3 John Q. Trojanowski United States 286k citations
  4. 4 Chris Sander United States 276k citations
  5. 5 Heng Li United States 270k citations
  6. 6 Xiaogang Wang China 260k citations
  7. 7 Didier Raoult France 232k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Biochemical and Structural Characterization?

The most cited paper in Biochemical and Structural Characterization is "Integrins: Versatility, modulation, and signaling in cell adhesion" (Richard O. Hynes, 1992), with 9,972 citations. Next come "Principles that Govern the Folding of Protein Chains" (7,215) and "Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd" (5,661).

Most cited papers
#PaperReleasedCitations
1 Integrins: Versatility, modulation, and signaling in cell adhesion Richard O. Hynes · Cell Apr 1992 9,972
2 Principles that Govern the Folding of Protein Chains Christian B. Anfinsen · Science 20 Jul 1973 7,215
3 Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd Robert D Fleischmann et al. · Science 28 Jul 1995 5,661
4 Fingerprinting genomes using PCR with arbitrary primers John B. Welsh, Michael McClelland · Nucleic Acids Research Open access 1990 5,224
5 Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies Robert E. W. Hancock, Hans‐Georg Sahl · Nature Biotechnology Dec 2006 4,225
All 99 most cited papers, with filters and sorting

Where is Biochemical and Structural Characterization research done?

The largest centres of Biochemical and Structural Characterization research in 2022-now are Beijing (China), Shanghai (China), Moscow (Russia) and Tehran (Iran). Among places with at least 20 works in it, it is an unusually large share of all research in Denpasar.

Largest cities, 2022-now

  1. 1 BeijingChina 107 works
  2. 2 ShanghaiChina 46 works
  3. 3 MoscowRussia 44 works
  4. 4 TehranIran 33 works
  5. 5 GuangzhouChina 32 works
  6. 6 ParisFrance 32 works
  7. 7 HangzhouChina 31 works
  8. 8 NanjingChina 31 works
  9. 9 SeoulSouth Korea 27 works
  10. 10 TokyoJapan 26 works

Where it is the local speciality

  1. DenpasarID · 20.7 works4.1×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Biochemical and Structural Characterization than the world average.

See Biochemical and Structural Characterization on the map

Where is the best place to study Biochemical and Structural Characterization?

Among universities, judged by research, The University of Queensland, Zhejiang University and Northeast Agricultural University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 11.31%fractional works in this field (log) →share of work in the world top 10% →Northeast Agricultur…Zhejiang UniversityThe University of Qu…Udayana University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1The University of QueenslandAustralia 65.210.8%6.0×17 -43.8%
2Zhejiang UniversityChina 57.227.2%1.5×12 +82.0%
3Northeast Agricultural UniversityChina 53.331.6%10.8×9 -22.2%
4Udayana UniversityIndonesia 49.10.0%8.2×19 +75.0%
5Harvard UniversityUnited States 46.512.6%1.2×11 -44.0%
6Shanghai Jiao Tong UniversityChina 33.711.1%1.2×11 -1.4%
7Vellore Institute of Technology UniversityIndia 27.415.8%2.8×8 -1.3%
8Universidad Nacional Autónoma de MéxicoMexico 25.82.9%2.7×8 +89.0%
9University of North Carolina at Chapel HillUnited States 22.41.1%2.0×11 -34.9%
10University of BaghdadIraq 17.50.0%3.7×8 +178.8%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Biochemical and Structural Characterization, country by country

Is Biochemical and Structural Characterization research growing?

Output in 2022-2025 was 8% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Biochemical and Structural Characterization.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Biochemical and Structural Characterization as a percentage of every work published that year, 0.014% in 2024.

still counting0.020%0.040%Biochemical and Structural Characterization0.014% in 202519801990200020102020

Fractional works of Biochemical and Structural Characterization over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Biochemical and Structural Characterization10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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