Science Explorer Interactive view Map

Bone Metabolism and Diseases

Bone Metabolism and Diseases is a research topic within Molecular Biology. Science Explorer counts 29k research works in it since 1950. 19.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the molecular mechanisms underlying osteoclast differentiation, bone resorption, and the regulation of bone homeostasis. It delves into the signaling pathways, transcription factors, and cytokines involved in osteoclast and osteoblast differentiation, as well as the interplay between the immune system and bone metabolism. Additionally, it investigates the impact of oxidative stress and inflammatory cytokines on bone remodeling.

  • Osteoclast Differentiation
  • Bone Resorption
  • RANKL Signaling
  • Osteoblast Differentiation
  • Bone Formation
  • Regulation of Bone Homeostasis
  • Osteoprotegerin
  • Tumor Necrosis Factor-a
  • Oxidative Stress
  • Immune System Interactions
Research works
29k
fractional, since 1950
In the world top 10%
5.7k
per year above
Top-10% rate
19.8%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+6%
the tick is no change

Which countries lead Bone Metabolism and Diseases research?

By volume, China and the United States publish the most (1.9k and 421 works in 2022–2025).

By volume, 2022–2025

  1. 1 China 1.9k works
  2. 2 United States 421 works
  3. 3 Japan 222 works
  4. 4 India 170 works
  5. 5 South Korea 166 works
  6. 6 Germany 112 works
  7. 7 Italy 86 works
  8. 8 United Kingdom 83 works
  9. 9 Brazil 69 works
  10. 10 Iran 60 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 58.0%United States: 12.7%Japan: 6.7%India: 5.1%6 others listed: 17.4%58%largest
China1,922 · 58.0%United States421 · 12.7%Japan222 · 6.7%India170 · 5.1%6 others listed576 · 17.4%

Shares of the rows listed above, not of the whole node.

Which institutions lead Bone Metabolism and Diseases research?

By volume in 2022–2025, Sichuan University publishes the most Bone Metabolism and Diseases research, followed by Stomatology Hospital and Shanghai Jiao Tong University.

Who are the leading researchers in Bone Metabolism and Diseases?

The most-cited researchers publishing on Bone Metabolism and Diseases include Cyrus Cooper and André G. Uitterlinden.

  1. 1 Cyrus Cooper United Kingdom 7.2k citations
  2. 2 André G. Uitterlinden Netherlands 4.4k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Bone Metabolism and Diseases research done?

The largest centres of Bone Metabolism and Diseases research in 2022–2025 are Shanghai (China), Beijing (China), Guangzhou (China) and Xi'an (China). Among places with at least 20 works in it, it is an unusually large share of all research in Wenzhou and Nanning.

Largest cities, 2022–2025

  1. 1 Shanghai China 170 works
  2. 2 Beijing China 162 works
  3. 3 Guangzhou China 148 works
  4. 4 Xi'an China 92 works
  5. 5 Hangzhou China 89 works
  6. 6 Wuhan China 71 works
  7. 7 Nanjing China 71 works
  8. 8 Jinan China 63 works
  9. 9 Chengdu China 59 works
  10. 10 Seoul South Korea 59 works

Where it is the local speciality

  1. WenzhouCN · 28.7 works8.1×
  2. NanningCN · 30.0 works5.8×
← less than its size predictsmore →

Location quotient: how much more of its research is in Bone Metabolism and Diseases than the world average.

See Bone Metabolism and Diseases on the map

Where is the best place to study Bone Metabolism and Diseases?

Among universities, judged by research, Guangzhou University of Chinese Medicine, Wenzhou Medical University and Zhejiang Chinese Medical University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 26.6%fractional works in this node (log) →share in the world top 10% →Guangzhou University of Chinese Medicine: 24, 23.4%Wenzhou Medical University: 18, 33.2%Zhejiang Chinese Medical University: 24, 30.0%Southern Medical University: 17, 27.1%Nanjing University of Chinese Medicine: 20, 23.6%Nanjing Medical University: 20, 23.3%China Medical University: 14, 30.0%Dalian Medical University: 8, 30.2%Sichuan University: 30, 27.5%Guangxi Medical University: 11, 17.7%Wenzhou Medical Univ…Zhejiang Chinese Med…Southern Medical Uni…Guangzhou University…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Guangzhou University of Chinese MedicineChina 72.223.4%31.4×24 +196.1%
2 Wenzhou Medical UniversityChina 67.233.2%12.6×18 +41.0%
3 Zhejiang Chinese Medical UniversityChina 66.430.0%23.9×24 +21.8%
4 Southern Medical UniversityChina 62.027.1%12.0×17 +25.4%
5 Nanjing University of Chinese MedicineChina 61.323.6%19.6×20 +81.2%
6 Nanjing Medical UniversityChina 60.623.3%9.9×20 +43.3%
7 China Medical UniversityChina 58.930.0%11.0×14 +9.4%
8 Dalian Medical UniversityChina 58.030.2%11.1×8 +132.1%
9 Sichuan UniversityChina 56.627.5%4.3×30 +73.3%
10 Guangxi Medical UniversityChina 53.417.7%16.6×11 +169.1%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Bone Metabolism and Diseases research growing?

Output in 2018–2022 was 6% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Bone Metabolism and Diseases.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.