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Topic · Molecular Biology

Genomics, phytochemicals, and oxidative stress

Genomics, phytochemicals, and oxidative stress is a research topic within Molecular Biology. Science Explorer counts 28k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the role of Nrf2 signaling in oxidative stress response, including its activation by oxidative stress, regulation of antioxidant gene expression, and its impact on cancer, inflammation, and chemoprevention. The Keap1-Nrf2-ARE pathway and the chemical diversity of glucosinolates are also central to this topic.

  • Nrf2
  • Oxidative Stress
  • Keap1-Nrf2-ARE Pathway
  • Glucosinolates
  • Antioxidant Response Element
  • Cancer
  • Inflammation
  • Chemoprevention
  • Redox Homeostasis
  • Transcription Regulation
Research works
28k
fractional, since 1950
In the world top 10%
2.7k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+7%
the tick is no change
Largest producer
China
52% of the 10 largest, 2022-now
Genomics, phytochemicals, and oxidative stress

Which countries lead Genomics, phytochemicals, and oxidative stress research?

By volume, China and the United States publish the most (2.2k and 521 works in 2022-now).

By volume, 2022-now

  1. 1 China 2.2k works
  2. 2 United States 521 works
  3. 3 India 394 works
  4. 4 South Korea 256 works
  5. 5 Japan 185 works
  6. 6 Italy 159 works
  7. 7 Türkiye 129 works
  8. 8 Egypt 123 works
  9. 9 Iran 122 works
  10. 10 Spain 110 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 51.8%United States: 12.5%India: 9.5%South Korea: 6.2%6 others listed: 19.9%52%largest
China2,152 · 51.8%United States521 · 12.5%India394 · 9.5%South Korea256 · 6.2%6 others listed828 · 19.9%

Shares of the rows listed above, not of the whole node.

Which institutions lead Genomics, phytochemicals, and oxidative stress research?

By volume in 2022-now, Chinese Academy of Agricultural Sciences publishes the most Genomics, phytochemicals, and oxidative stress research, followed by Chinese Academy of Sciences and Zhejiang University.

By volume, 2022-now

  1. 1 Chinese Academy of Agricultural SciencesChina 69 works
  2. 2 Chinese Academy of SciencesChina 36 works
  3. 3 Zhejiang UniversityChina 30 works
  4. 4 Wenzhou Medical UniversityChina 28 works
  5. 5 Jilin UniversityChina 28 works
  6. 6 Nanjing Medical UniversityChina 26 works
  7. 7 Shanghai Jiao Tong UniversityChina 23 works
  8. 8 Russian Academy of SciencesRussia 23 works
  9. 9 Ministry of Agriculture and Rural AffairsChina 23 works
  10. 10 Northeast Agricultural UniversityChina 23 works

Who are the leading researchers in Genomics, phytochemicals, and oxidative stress?

The most-cited researchers publishing on Genomics, phytochemicals, and oxidative stress include Walter Churchill Willett, Guido Kroemer and John J.V. McMurray.

  1. 1 Walter Churchill Willett United States 411k citations
  2. 2 Guido Kroemer France 386k citations
  3. 3 John J.V. McMurray United Kingdom 349k citations
  4. 4 Hermann Brenner Germany 343k citations
  5. 5 Jun Wang China 340k citations
  6. 6 Giuseppe Remuzzi Italy 328k citations
  7. 7 Luigi Ferrucci United States 281k citations
  8. 8 Frank B. Hu United States 281k citations
  9. 9 Reza Malekzadeh Iran 278k citations
  10. 10 Michael Karin United States 276k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Genomics, phytochemicals, and oxidative stress?

The most cited paper in Genomics, phytochemicals, and oxidative stress is "Glutathione S-Transferases" (William H. Habig, Michael J Pabst, William B. Jakoby, 1974), with 18,239 citations. Next come "Oxidative stress, antioxidants and stress tolerance" (10,890) and "Free Radicals in the Physiological Control of Cell Function" (9,887).

Most cited papers
#PaperReleasedCitations
1 Glutathione S-Transferases William H. Habig, Michael J Pabst, William B. Jakoby · Journal of Biological Chemistry Open access Nov 1974 18,239
2 Oxidative stress, antioxidants and stress tolerance Ron Mittler · Trends in Plant Science Review Sep 2002 10,890
3 Free Radicals in the Physiological Control of Cell Function Wulf Dröge · Physiological Reviews Review 2002 9,887
4 The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals Jia Zhishen, Tang Mengcheng, Jianming Wu · Food Chemistry Mar 1999 8,838
5 ROS Function in Redox Signaling and Oxidative Stress Michael Schieber, Navdeep S. Chandel · Current Biology Open access May 2014 6,967
All 100 most cited papers, with filters and sorting

Where is Genomics, phytochemicals, and oxidative stress research done?

The largest centres of Genomics, phytochemicals, and oxidative stress research in 2022-now are Beijing (China), Guangzhou (China), Shanghai (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Wenzhou.

Largest cities, 2022-now

  1. 1 BeijingChina 202 works
  2. 2 GuangzhouChina 115 works
  3. 3 ShanghaiChina 100 works
  4. 4 NanjingChina 99 works
  5. 5 SeoulSouth Korea 84 works
  6. 6 WuhanChina 83 works
  7. 7 HangzhouChina 81 works
  8. 8 ChongqingChina 61 works
  9. 9 ChengduChina 61 works
  10. 10 ChangshaChina 60 works

Where it is the local speciality

  1. WenzhouCN · 35.0 works7.4×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Genomics, phytochemicals, and oxidative stress than the world average.

See Genomics, phytochemicals, and oxidative stress on the map

Where is the best place to study Genomics, phytochemicals, and oxidative stress?

Among universities, judged by research, Chengdu University of Traditional Chinese Medicine, Sichuan University and Northeast Agricultural University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 20.63%fractional works in this field (log) →share of work in the world top 10% →Sichuan UniversityChengdu University o…Northeast Agricultur…Wenzhou Medical Univ…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Chengdu University of Traditional Chinese MedicineChina 73.427.1%14.7×18 +112.8%
2Sichuan UniversityChina 70.930.1%2.1×22 +61.2%
3Northeast Agricultural UniversityChina 68.718.9%18.4×23 +36.7%
4Wenzhou Medical UniversityChina 61.810.3%12.0×28 +36.1%
5China Agricultural UniversityChina 61.220.1%6.3×16 +16.8%
6Jilin UniversityChina 59.217.9%5.1×28 -19.7%
7Shanghai University of Traditional Chinese MedicineChina 58.916.5%14.5×19 +109.6%
8Zunyi Medical UniversityChina 57.035.2%10.3×8 +6.2%
9Zhejiang UniversityChina 56.211.0%2.4×30 -4.5%
10Tohoku UniversityJapan 54.619.2%5.0×16 -14.1%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Genomics, phytochemicals, and oxidative stress, country by country

Is Genomics, phytochemicals, and oxidative stress research growing?

Output in 2022-2025 was 7% higher than in 2018-2021, peaking in 2022. The fastest-growing topics are Genomics, phytochemicals, and oxidative stress.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Genomics, phytochemicals, and oxidative stress as a percentage of every work published that year, 0.021% in 2024.

still counting0.020%0.040%Genomics, phytochemicals, and oxidative stress0.021% in 202519801990200020102020

Fractional works of Genomics, phytochemicals, and oxidative stress over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Genomics, phytochemicals, and oxidative stress9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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