Cell death mechanisms and regulation
Cell death mechanisms and regulation is a research topic within Molecular Biology. Science Explorer counts 32k research works in it since 1951. 24.1% of them reached the world's top 10% most cited for their field and year.
This cluster of papers explores the molecular mechanisms, regulation, and implications of apoptosis and other forms of cell death, with a focus on the roles of Bcl-2 family proteins, mitochondria, TNF signaling, caspases, and reactive oxygen species. It also delves into the application of these insights in cancer therapy.
- Apoptosis
- Cell Death
- Bcl-2 Family
- Mitochondria
- TNF Signaling
- Caspases
- Reactive Oxygen Species
- Necroptosis
- Programmed Cell Death
- Cancer Therapy
- Research works
- 32k fractional, since 1951
- In the world top 10%
- 7.7k per year above
- Top-10% rate
- 24.1% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- -19% the tick is no change
Which countries lead Cell death mechanisms and regulation research?
By volume, China and the United States publish the most (1k and 439 works in 2022–2025).
By volume, 2022–2025
- 1 China 1k works
- 2 United States 439 works
- 3 India 149 works
- 4 South Korea 100 works
- 5 Japan 96 works
- 6 Germany 91 works
- 7 Iran 84 works
- 8 Türkiye 67 works
- 9 United Kingdom 60 works
- 10 France 59 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead Cell death mechanisms and regulation research?
By volume in 2022–2025, Central South University publishes the most Cell death mechanisms and regulation research, followed by Chinese Academy of Medical Sciences & Peking Union Medical College and Sun Yat-sen University.
By volume, 2022–2025
- 1 Central South UniversityChina 13 works
- 2 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 13 works
- 3 Sun Yat-sen UniversityChina 12 works
- 4 Nanjing Medical UniversityChina 12 works
- 5 University of North Carolina at Chapel HillUnited States 11 works
- 6 St. Jude Children's Research HospitalUnited States 11 works
- 7 Soochow UniversityChina 11 works
- 8 Wenzhou Medical UniversityChina 10 works
- 9 Sichuan UniversityChina 10 works
- 10 Fujian Medical UniversityChina 10 works
Who are the leading researchers in Cell death mechanisms and regulation?
The most-cited researchers publishing on Cell death mechanisms and regulation include Alberto Ortíz, Guido Kroemer and Bharat B. Aggarwal.
- 1 Alberto Ortíz Spain 5.9k citations
- 2 Guido Kroemer France 4.2k citations
- 3 Bharat B. Aggarwal United States 4.2k citations
- 4 Michael Karin United States 4k citations
- 5 Peter R. Galle Germany 3.3k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is Cell death mechanisms and regulation research done?
The largest centres of Cell death mechanisms and regulation research in 2022–2025 are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China).
Where is the best place to study Cell death mechanisms and regulation?
Among universities, judged by research, Fujian Medical University, Chinese Academy of Medical Sciences & Peking Union Medical College and Nanjing Medical University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | Fujian Medical UniversityChina | 60.3 | 19.1% | 10.4× | 10 | +94.9% |
| 2 | Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina | 55.0 | 30.4% | 5.0× | 13 | -8.5% |
| 3 | Nanjing Medical UniversityChina | 54.1 | 24.9% | 8.5× | 12 | -19.4% |
| 4 | China Pharmaceutical UniversityChina | 53.4 | 29.7% | 14.1× | 8 | +31.9% |
| 5 | Wenzhou Medical UniversityChina | 50.6 | 16.8% | 10.8× | 10 | +16.9% |
| 6 | Central South UniversityChina | 47.9 | 27.9% | 2.9× | 13 | -12.4% |
| 7 | Sun Yat-sen UniversityChina | 46.2 | 29.2% | 2.9× | 12 | -14.7% |
| 8 | The University of MelbourneAustralia | 44.4 | 39.9% | 3.1× | 8 | -1.9% |
| 9 | Soochow UniversityChina | 38.9 | 16.9% | 4.9× | 11 | +10.6% |
| 10 | Sichuan UniversityChina | 30.0 | 26.2% | 2.2× | 10 | -33.2% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is Cell death mechanisms and regulation research growing?
Output in 2018–2022 was 19% lower than in 2013–2017, peaking in 2003.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.