Muscle Physiology and Disorders

Muscle Physiology and Disorders is a research topic within Molecular Biology. Science Explorer counts 39k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the molecular mechanisms underlying muscle regeneration, satellite cell function, myostatin regulation, ubiquitin ligases, and the role of various signaling pathways such as IGF-1/PI3K/Akt in preventing skeletal muscle atrophy. It also delves into the interaction between inflammatory processes and muscle injury, as well as the involvement of dystrophin in muscle function and disease. The research encompasses a wide range of topics related to muscle biology and potential therapeutic targets for muscle-related disorders.

Muscle Regeneration
Skeletal Muscle Atrophy
Satellite Cells
Myostatin
Ubiquitin Ligases
Stem Cells
FoxO Transcription Factors
Dystrophin
IGF-1/PI3K/Akt Pathway
Inflammatory Processes

Research works: 39k
In the world top 10%: 3.8k
Top-10% rate: 10.0%
Growth, 2018-21 → 2022-25: +5%
Largest producer: United States

Muscle Physiology and Disorders

Which countries lead Muscle Physiology and Disorders research?

By volume, the United States and China publish the most (1.7k and 1.2k works in 2022-now).

By volume, 2022-now

1 United States 1.7k works
2 China 1.2k works
3 Japan 463 works
4 United Kingdom 307 works
5 Italy 300 works
6 France 263 works
7 South Korea 255 works
8 Canada 229 works
9 Germany 216 works
10 India 179 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States1,658 · 33.0%China1,157 · 23.0%Japan463 · 9.2%United Kingdom307 · 6.1%6 others listed1,442 · 28.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Muscle Physiology and Disorders research?

By volume in 2022-now, Centre National de la Recherche Scientifique publishes the most Muscle Physiology and Disorders research, followed by Inserm and Russian Academy of Sciences.

By volume, 2022-now

1 Centre National de la Recherche ScientifiqueFrance 63 works
2 InsermFrance 56 works
3 Russian Academy of SciencesRussia 52 works
4 The Ohio State UniversityUnited States 51 works
5 Harvard UniversityUnited States 48 works
6 University College LondonUnited Kingdom 43 works
7 National Institutes of HealthUnited States 33 works
8 University of FloridaUnited States 31 works
9 Sichuan UniversityChina 30 works
10 University of CincinnatiUnited States 30 works

Who are the leading researchers in Muscle Physiology and Disorders?

The most-cited researchers publishing on Muscle Physiology and Disorders include Mark J. Daly, Guido Kroemer and Cyrus Cooper.

1 Mark J. Daly United States 403k citations
2 Guido Kroemer France 386k citations
3 Cyrus Cooper United Kingdom 342k citations
4 Valery L. Feigin New Zealand 341k citations
5 Jun Wang China 340k citations
6 Gregory Y.H. Lip United Kingdom 311k citations
7 Matthias Mann Germany 308k citations
8 Róbert Langer United States 303k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Muscle Physiology and Disorders?

The most cited paper in Muscle Physiology and Disorders is "Multilineage Potential of Adult Human Mesenchymal Stem Cells" (Mark F. Pittenger, Alastair M. Mackay, Stephen C. Beck et al., 1999), with 21,222 citations. Next come "Calcium's Role in Mechanotransduction during Muscle Development" (14,545) and "Multilineage Cells from Human Adipose Tissue: Implications for Cell-Based Therapies" (8,044).

Most cited papers
#	Paper	Released	Citations
1	Multilineage Potential of Adult Human Mesenchymal Stem Cells Mark F. Pittenger, Alastair M. Mackay, Stephen C. Beck et al. · Science	2 Apr 1999	21,222
2	Calcium's Role in Mechanotransduction during Muscle Development Tatiana Benavides Damm, Marcel Egli · Cellular Physiology and Biochemistry Open access	2014	14,545
3	Multilineage Cells from Human Adipose Tissue: Implications for Cell-Based Therapies Patricia A. Zuk, Min Zhu, Hiroshi Mizuno et al. · Tissue Engineering	Apr 2001	8,044
4	Human Adipose Tissue Is a Source of Multipotent Stem Cells Patricia A. Zuk, Min Zhu, Peter H. Ashjian et al. · Molecular Biology of the Cell Open access	Dec 2002	6,709
5	Dystrophin: The protein product of the duchenne muscular dystrophy locus Eric P. Hoffman, Robert H. Brown, Louis M. Kunkel · Cell	Dec 1987	4,742

All 100 most cited papers, with filters and sorting

Where is Muscle Physiology and Disorders research done?

The largest centres of Muscle Physiology and Disorders research in 2022-now are Beijing (China), Tokyo (Japan), Paris (France) and London (United Kingdom).

Largest cities, 2022-now

1 BeijingChina 163 works
2 TokyoJapan 150 works
3 ParisFrance 128 works
4 LondonUnited Kingdom 114 works
5 SeoulSouth Korea 101 works
6 ShanghaiChina 95 works
7 GuangzhouChina 72 works
8 MoscowRussia 67 works
9 RomeItaly 57 works
10 MilanItaly 57 works

See Muscle Physiology and Disorders on the map

Where is the best place to study Muscle Physiology and Disorders?

Among universities, judged by research, Nantong University, Karolinska Institutet and Harvard University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged

40%

Specialisationhow much of its work is in this field, counted up to 10× the world share

10%

Sizeits output in this field, on a log scale

30%

Growthoutput growth, counted from -20% to +20%

10%

Internationalshare of its work with a co-author abroad

10%

Each slider sets a weight; the share it gets of the score is beside it.

#	University	Score	Top 10%	Specialisation	Works	Growth
1	Nantong UniversityChina	63.4	41.2%	4.5×	12	+36.8%
2	Karolinska InstitutetSweden	58.7	12.9%	6.8×	22	+17.3%
3	Harvard UniversityUnited States	58.6	12.0%	2.6×	48	-15.6%
4	University College LondonUnited Kingdom	55.7	11.3%	4.7×	43	-12.6%
5	McGill UniversityCanada	55.4	12.7%	4.4×	25	+33.2%
6	University of OttawaCanada	54.4	14.1%	6.8×	26	-0.3%
7	University of CincinnatiUnited States	53.7	9.3%	8.8×	30	+30.7%
8	University of SharjahUnited Arab Emirates	53.3	22.9%	5.4×	8	+160.6%
9	KU LeuvenBelgium	53.1	13.0%	3.9×	21	+30.1%
10	Radboud University NijmegenNetherlands	52.8	7.6%	7.4×	26	+13.0%
11	Sichuan UniversityChina	52.7	14.7%	2.3×	30	+234.1%
12	University of PaduaItaly	51.2	15.6%	5.3×	24	+2.7%
13	Stanford UniversityUnited States	50.5	14.3%	2.3×	20	-2.0%
14	The Ohio State UniversityUnited States	49.7	7.6%	7.3×	51	-26.7%
15	Maastricht UniversityNetherlands	49.5	24.6%	5.7×	13	-14.8%
16	University of Arkansas at FayettevilleUnited States	48.7	14.3%	13.2×	17	+50.5%
17	University of FloridaUnited States	48.3	12.1%	5.1×	32	-19.1%
18	Zhejiang UniversityChina	48.1	17.0%	1.5×	22	+73.7%
19	McMaster UniversityCanada	47.6	22.4%	4.2×	14	-15.6%
20	Leiden UniversityNetherlands	47.5	7.0%	8.3×	26	-7.8%
21	University of California, Los AngelesUnited States	47.2	11.8%	3.1×	20	+29.8%
22	Southern Medical UniversityChina	47.1	29.2%	3.0×	11	+12.7%
23	University of California, DavisUnited States	46.7	12.9%	3.9×	18	+23.6%
24	Università Cattolica del Sacro CuoreItaly	46.5	17.3%	5.9×	14	+10.1%
25	University of CopenhagenDenmark	45.8	11.6%	3.9×	21	-17.0%
26	Shanghai Jiao Tong UniversityChina	45.5	14.5%	1.5×	24	+34.7%
27	York UniversityCanada	45.5	21.6%	5.5×	11	+13.1%
28	Duke UniversityUnited States	45.3	13.8%	3.9×	18	+4.5%
29	Peking UniversityChina	44.9	11.6%	2.0×	24	+42.5%
30	Indiana UniversityUnited States	44.0	10.0%	4.7×	26	-7.3%
31	University of AlbertaCanada	44.0	13.9%	3.6×	18	+1.7%
32	Johns Hopkins UniversityUnited States	43.4	15.3%	2.3×	20	-19.9%
33	Chinese University of Hong KongChina	43.2	13.8%	2.4×	10	+86.5%
34	Central South UniversityChina	42.5	16.2%	1.6×	17	+44.7%
35	China Agricultural UniversityChina	42.4	22.8%	3.4×	11	+25.2%
36	University of WashingtonUnited States	41.5	14.5%	2.9×	19	-5.9%
37	Fudan UniversityChina	41.4	12.7%	2.1×	19	+39.9%
38	Washington University in St. LouisUnited States	41.2	7.3%	3.6×	15	+10.9%
39	Northwest A&F UniversityChina	40.9	13.8%	6.3×	14	+85.9%
40	Newcastle UniversityUnited Kingdom	40.8	12.0%	6.3×	17	-11.9%
41	University of KentuckyUnited States	40.8	17.3%	5.7×	15	-39.6%
42	National University of SingaporeSingapore	38.6	17.1%	1.3×	9	+52.3%
43	Universidade de São PauloBrazil	37.1	4.3%	2.5×	29	-3.3%
44	Brock UniversityCanada	35.2	11.5%	13.9×	9	+57.3%
45	University of BaselSwitzerland	33.1	16.7%	4.2×	9	-20.0%
46	University of Massachusetts Chan Medical SchoolUnited States	32.3	7.3%	11.1×	11	+1.9%
47	Augusta UniversityUnited States	32.3	3.1%	9.0×	9	+37.4%
48	University of LiverpoolUnited Kingdom	31.8	6.6%	3.5×	11	+1.4%
49	Sichuan Agricultural UniversityChina	31.0	12.6%	8.8×	14	-30.5%
50	University of PerugiaItaly	29.2	7.6%	9.8×	12	-25.0%
51	Juntendo UniversityJapan	17.9	5.6%	9.0×	8	-49.8%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Muscle Physiology and Disorders, country by country

Is Muscle Physiology and Disorders research growing?

Output in 2022-2025 was 5% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Muscle Physiology and Disorders.

grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Muscle Physiology and Disorders as a percentage of every work published that year, 0.024% in 2024.

Fractional works of Muscle Physiology and Disorders over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

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Which countries lead Muscle Physiology and Disorders research?

By volume, 2022-now

How concentrated that is

Which institutions lead Muscle Physiology and Disorders research?

By volume, 2022-now

Who are the leading researchers in Muscle Physiology and Disorders?

What are the most cited papers in Muscle Physiology and Disorders?

Where is Muscle Physiology and Disorders research done?

Largest cities, 2022-now

Where is the best place to study Muscle Physiology and Disorders?

Is Muscle Physiology and Disorders research growing?

Its share of all research

How much of it reaches the world top 10%

Which topics inside it are moving

Related research

Discussion