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Topic · Molecular Biology

Congenital heart defects research

Congenital heart defects research is a research topic within Molecular Biology. Science Explorer counts 29k research works in it since 1950. 20.3% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the molecular mechanisms underlying cardiac development, regeneration, and congenital heart defects. It covers topics such as cardiomyocyte renewal, cardiac progenitor populations, endothelial cell-lineage analysis, neural crest contributions, epicardial progenitors, Wnt signaling, T-box genes, and the potential of microRNA therapy for cardiac regeneration.

  • Cardiomyocyte Renewal
  • Heart Regeneration
  • Cardiac Progenitor Population
  • Congenital Heart Defects
  • Endothelial Cell-Lineage Analysis
  • Neural Crest
  • Epicardial Progenitors
  • Wnt Signaling
  • T-Box Genes
  • MicroRNA Therapy
Research works
29k
fractional, since 1950
In the world top 10%
6k
per year above
Top-10% rate
20.3%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+5%
the tick is no change

Which countries lead Congenital heart defects research research?

By volume, the United States and China publish the most (1.3k and 815 works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 1.3k works
  2. 2 China 815 works
  3. 3 United Kingdom 215 works
  4. 4 Japan 199 works
  5. 5 Germany 190 works
  6. 6 Italy 157 works
  7. 7 India 146 works
  8. 8 France 125 works
  9. 9 Canada 125 works
  10. 10 Spain 102 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 38.0%China: 24.3%United Kingdom: 6.4%Japan: 5.9%6 others listed: 25.3%38%largest
United States1,272 · 38.0%China815 · 24.3%United Kingdom215 · 6.4%Japan199 · 5.9%6 others listed846 · 25.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Congenital heart defects research research?

By volume in 2022–2025, University of North Carolina at Chapel Hill publishes the most Congenital heart defects research research, followed by Harvard University and Chinese Academy of Medical Sciences & Peking Union Medical College.

By volume, 2022–2025

  1. 1 University of North Carolina at Chapel HillUnited States 24 works
  2. 2 Harvard UniversityUnited States 22 works
  3. 3 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 21 works
  4. 4 Children's Hospital of PhiladelphiaUnited States 20 works
  5. 5 University of PennsylvaniaUnited States 19 works
  6. 6 Stanford UniversityUnited States 18 works
  7. 7 Baylor College of MedicineUnited States 18 works
  8. 8 InsermFrance 16 works
  9. 9 Boston Children's HospitalUnited States 16 works
  10. 10 Cincinnati Children's Hospital Medical CenterUnited States 14 works

Where is Congenital heart defects research research done?

The largest centres of Congenital heart defects research research in 2022–2025 are Beijing (China), Shanghai (China), London (United Kingdom) and Guangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Cincinnati, Philadelphia and Columbus.

Largest cities, 2022–2025

  1. 1 Beijing China 124 works
  2. 2 Shanghai China 103 works
  3. 3 London United Kingdom 81 works
  4. 4 Guangzhou China 67 works
  5. 5 Paris France 62 works
  6. 6 Boston United States 56 works
  7. 7 Philadelphia United States 56 works
  8. 8 Tokyo Japan 54 works
  9. 9 New York United States 48 works
  10. 10 Houston United States 46 works

Where it is the local speciality

  1. CincinnatiUS · 25.5 works7.6×
  2. PhiladelphiaUS · 55.7 works5.0×
  3. ColumbusUS · 27.9 works4.8×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Congenital heart defects research than the world average.

See Congenital heart defects research on the map

Where is the best place to study Congenital heart defects research?

Among universities, judged by research, Baylor College of Medicine, Karolinska Institutet and Harvard University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 22.92%fractional works in this node (log) →share in the world top 10% →Baylor College of Medicine: 18, 20.7%Karolinska Institutet: 9, 34.2%Harvard University: 22, 24.5%University of Colorado Anschutz Medical Campus: 12, 16.4%Guangzhou Medical University: 9, 16.7%University of Pennsylvania: 19, 21.1%Stanford University: 18, 22.3%King's College London: 11, 27.8%University of Oxford: 11, 29.6%Chinese Academy of Medical Sciences & Peking Union Medical College: 21, 15.9%Karolinska InstitutetHarvard UniversityBaylor College of Me…University of Colora…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Baylor College of MedicineUnited States 61.020.7%10.4×18 +29.7%
2 Karolinska InstitutetSweden 54.734.2%4.7×9 +23.8%
3 Harvard UniversityUnited States 54.024.5%4.1×22 -8.0%
4 University of Colorado Anschutz Medical CampusUnited States 51.016.4%10.0×12 +75.5%
5 Guangzhou Medical UniversityChina 48.016.7%8.2×9 +162.8%
6 University of PennsylvaniaUnited States 46.121.1%4.9×19 -20.4%
7 Stanford UniversityUnited States 46.122.3%3.5×18 +31.9%
8 King's College LondonUnited Kingdom 43.227.8%3.5×11 -12.9%
9 University of OxfordUnited Kingdom 41.029.6%2.1×11 -22.6%
10 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 40.915.9%5.1×21 -26.4%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Congenital heart defects research research growing?

Output in 2018–2022 was 5% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Congenital heart defects research.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.